Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Walter F. Heine"'
Publikováno v:
Journal of Clinical Neurophysiology. 37:263-270
PURPOSE High-density EEG (HD-EEG) systems and electrical source imaging techniques have revolutionized our ability to assess the potential sources of epileptiform activity and other EEG features. Nonetheless, clinical use of HD-EEG is hampered by the
Publikováno v:
Clinical Neurophysiology. 129:e99-e100
Introduction High density EEG (hdEEG) systems and Electrical Source Imaging (ESI) techniques have revolutionized our ability to assess the potential sources of epileptiform activity and other EEG features. HdEEG interpretation is limited by lack of s
Publikováno v:
Visual Neuroscience. 28:403-417
The rat is a popular animal model for vision research, yet there is little quantitative information about the physiological properties of the cells that provide its brain with visual input, the retinal ganglion cells. It is not clear whether rats eve
Publikováno v:
Clinical Neurophysiology. 129:e70
Introduction Despite major advances in using high density EEG (hdEEG) and electrical source imaging (ESI) for analysis of interictal activity, research demonstrating its utility in examining ictal activity is still lacking. This may be a result of te
Publikováno v:
Visual Neuroscience. 25:535-548
Action potentials were recorded from rat retinal ganglion cell fibers in the presence of a uniform field, and the maintained discharge pattern was characterized. Spike trains recorded under ketamine–xylazine anesthesia were generally stationary, wh
Publikováno v:
Experimental Neurology. 189:231-240
Regeneration in the peripheral nervous system is impaired after prolonged periods of denervation. Currently, no interventions exist to alter the outcome after prolonged denervation. To examine the role of transplanted neural stem cells (NSC), we prep
Autor:
Petr Jarolim, Igor B. Resnick, Ian M. Ahearn, David N. Ciccone, Walter F. Heine, Fred S. Rosen, Ronald A. DePinho, David T. Weaver, Velvizhi Ranganathan, Hua Hai, Eva Seemanova, Karl Lenhard Rudolph, Sandy Chang, Xiaohua Wu, David M. Livingston
Publikováno v:
Current Biology. 11:962-966
Nijmegen breakage syndrome (NBS) is a rare human disease displaying chromosome instability, radiosensitivity, cancer predisposition, immunodeficiency, and other defects [1, 2]. NBS is complexed with MRE11 and RAD50 in a DNA repair complex [3–5] and
Autor:
Kindra E. Crick, Kerry A. Pierce, David M. Livingston, Xiaohua Wu, Ted O’Neill, Walter F. Heine, Gary Rathbun, David S. Weisman, David T. Weaver, Velvizhi Ranganathan, David N. Ciccone, William S. Lane
Publikováno v:
Nature. 405:477-482
Nijmegen breakage syndrome (NBS) is characterized by extreme radiation sensitivity, chromosomal instability and cancer1. The phenotypes are similar to those of ataxia telangiectasia mutated (ATM) disease, where there is a deficiency in a protein kina
Publikováno v:
Journal of visualized experiments : JoVE. (38)
Information about the visual world is transmitted to the brain in sequences of action potentials in retinal ganglion cell axons that make up the optic nerve. In vivo recordings of ganglion cell spike trains in several animal models have revealed much
Autor:
David T. Weaver, David M. Livingston, John H.J. Petrini, Walter F. Heine, Junjie Chen, Xiaohua Wu
Publikováno v:
Science. 289:11a-11
The BRCA1 gene product plays a multifunctional role in controlling genome integrity. Embryonic stem cells lacking BRCA1 are reportedly defective in transcription-coupled repair of oxidative DNA damage ([1][1]). Cells lacking intact BRCA1 also manifes