Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Walter F. Bobrowski"'
Autor:
Carlin Okerberg, Timothy M. Coskran, Kou Kou, Walter F. Bobrowski, Irani Khatun, Nicholas B. Vera, Derek M. Erion, Bryan Goodwin, Ronald W. Clark
Publikováno v:
Journal of Biological Chemistry. 291:2602-2615
Dietary triglycerides (TG) are absorbed by the enterocytes of the small intestine after luminal hydrolysis into monacylglycerol and fatty acids. Before secretion on chylomicrons, these lipids are reesterified into TG, primarily through the monoacylgl
Autor:
Katherine Masek-Hammerman, Marie Debrue, Laurence O. Whiteley, Zaher A. Radi, Lindsay Tomlinson, Thomas P. Brown, Walter F. Bobrowski
Publikováno v:
Toxicologic pathology. 45(5)
Chronic prostatitis characterized on light microscopic examination by moderate, multifocal, predominantly lymphocytic inflammation associated with epithelial atypia and intranuclear and cytoplasmic inclusion-like material was identified in the prosta
Autor:
Srinivasa R. Mantena, Cynthia M. Rohde, Dean Messing, Sharon A. Sokolowski, John W. Davis, Michael I. Jesson, Karrie A. Brenneman, Shawn P. O'Neil, Lindsay Tomlinson, Christopher G. Leonard, Laurence O. Whiteley, Steven Bailey, Deborah C. Carraher, Walter F. Bobrowski, Zachary S. Stewart, Yutian Zhan, W. Mark Vogel, Kimberly M. Shevlin, Dale L. Morris, Hungyun Lin, Shashi K. Ramaiah, Lauren M. Gauthier
Publikováno v:
Toxicologic Pathology. 42:229-242
Pancreatic toxicity commonly affects the endocrine or exocrine pancreas. However, it can also occur at the endocrine–exocrine interface (EEI), where the capillary network of the islet merges with the capillaries of the surrounding acinar tissue, th
Autor:
Carlin Okerberg, Chris J. Somps, Matthew R. Zahner, Chang-Ning Liu, Alan C. Opsahl, Walter F. Bobrowski
Publikováno v:
Journal of pharmacological and toxicological methods. 80
The goal of this study was to determine the degree of sympathetic postganglionic neuronal loss required to impair cardiovascular-related sympathetic activity. To produce neuronal loss separate groups of rats were treated daily with guanethidine for e
Publikováno v:
Toxicologic Pathology. 41:32-37
Renal tubular inclusion bodies are rarely associated with drug administration. The authors describe the finding of renal cortical tubular intranuclear and intracytoplasmic inclusion bodies associated with the oral administration of a norepinephrine/s
Autor:
Daniel Morton, Walter F. Bobrowski, Ingrid D. Pardo, Klaus Weber, Jerry F. Hardisty, Robert H. Garman
Publikováno v:
Toxicologic Pathology. 40:624-636
For general toxicity studies, a technique was designed to consistently sample the most important neuroanatomic regions of the brain, spinal cord, and peripheral nerve of cynomolgus monkeys using a limited number of blocks and slides. Using the most r
Publikováno v:
Experimental Neurology. 180:55-73
The resulting neuropathological degeneration that occurs following a traumatic brain injury (TBI) is a consequence of both immediate and secondary neurochemical sequelae. Proteolysis of cytoskeletal proteins, triggered by calcium-mediated events, is
Autor:
Sangeetha Bollini, Mark G. Evans, Nasir K. Khan, Walter F. Bobrowski, Thomas P. Brown, Allison Vitsky, Niraj Tripathi, Bora Han, John C. Lin, Jennifer L. Rojko, Jonathan R. Heyen, Theodore O. Johnson, Shana Dalton
Publikováno v:
Toxicologic pathology. 42(4)
Two 6-month repeat-dose toxicity studies in cynomolgus monkeys illustrated immune complex–mediated adverse findings in individual monkeys and identified parameters that potentially signal the onset of immune complex–mediated reactions following a
Autor:
J. F. Reindel, Gregg Sobocinski, Alexander W. Gough, Gary D. Pilcher, Walter F. Bobrowski, Felix A. de la Iglesia
Publikováno v:
Toxicologic Pathology. 29:159-173
Epidermal growth factor (EGF) effects have been explored extensively in vivo in rodents, but little is known about trophic responses in nonhuman primates. A previous publication reports the hyperplastic epithelial/parenchymal changes noted in the dig
Autor:
A. W. Gough, Walter F. Bobrowski, Thomas M.A. Bocan, E. J. Mcguire, J. F. Reindel, Mark A. Dominick
Publikováno v:
Fundamental and Applied Toxicology. 20:217-224
Subacute Toxicity of a Novel Inhibitor of Acyl-CoA:Cholesterol Acyltransferase in Beagle Dogs. Dominick, M. A., McGuire, E. J., Reindel, J. F., Bobrowski, W. F., Bocan, T. M. A., and Gough, A. W. (1993). Fundam. Appl. Toxicol. 20, 217-224. PD 132301-