Zobrazeno 1 - 10
of 379
pro vyhledávání: '"Walter E. Müller"'
Autor:
Fiona von Buedingen, Marc S. Hammer, Andreas D. Meid, Walter E. Müller, Ferdinand M. Gerlach, Christiane Muth
Publikováno v:
BMC Family Practice, Vol 19, Iss 1, Pp 1-11 (2018)
Abstract Background Treatment complexity rises in line with the number of drugs, single doses, and administration methods, thereby threatening patient adherence. Patients with multimorbidity often need flexible, individualised treatment regimens, but
Externí odkaz:
https://doaj.org/article/b3c298a60cd346f784086e1a2fc86872
Publikováno v:
Neural Plasticity, Vol 2016 (2016)
The mitochondrial cascade hypothesis of dementia assumes mitochondrial dysfunction leading to reduced energy supply, impaired neuroplasticity, and finally cell death as one major pathomechanism underlying the continuum from brain aging over mild cogn
Externí odkaz:
https://doaj.org/article/013feda074a54b42822f73e5a8f14459
Autor:
Gunter P. Eckert, Gero P. Hooff, Dana M. Strandjord, Urule Igbavboa, Dietrich A. Volmer, Walter E. Müller, W. Gibson Wood
Publikováno v:
Neurobiology of Disease, Vol 35, Iss 2, Pp 251-257 (2009)
Post-translational modification of small GTPases by farnesyl- (FPP) and geranylgeranylpyrophosphate (GGPP) has generated much attention due to their potential contribution to cancer, cardiovascular and neurodegenerative diseases. Prenylated proteins
Externí odkaz:
https://doaj.org/article/df1568d819044ae8b23e59ecfa9a12a3
Autor:
Cornelia Franke, Michael Nöldner, Reham Abdel-Kader, Leslie N. Johnson-Anuna, W. Gibson Wood, Walter E. Müller, Gunter P. Eckert
Publikováno v:
Neurobiology of Disease, Vol 25, Iss 2, Pp 438-445 (2007)
The present study determined if chronic simvastatin administration in vivo would provide neuroprotection in brain cells isolated from guinea pigs after challenge with the Bcl-2 inhibitor HA 14-1 or the NO donor sodium nitroprusside (SNP). Bcl-2 level
Externí odkaz:
https://doaj.org/article/e09ff3bd71e34308aac6230501252a7a
Autor:
Katrin Schuessel, Stephanie Schäfer, Thomas A. Bayer, Christian Czech, Laurent Pradier, Franz Müller-Spahn, Walter E. Müller, Anne Eckert
Publikováno v:
Neurobiology of Disease, Vol 18, Iss 1, Pp 89-99 (2005)
Oxidative stress plays an important role in the pathogenesis of Alzheimer's disease. To determine which mechanisms cause the origin of oxidative damage, we analyzed enzymatic antioxidant defense (Cu/Zn-superoxide dismutase Cu/Zn-SOD, glutathione pero
Externí odkaz:
https://doaj.org/article/3fe3eeba90e64e07a67edced5036a3ca
Autor:
Anne Eckert, Katharina Schindowski, Silke Leutner, Christian Luckhaus, Nathalie Touchet, Christian Czech, Walter E. Müller
Publikováno v:
Neurobiology of Disease, Vol 8, Iss 2, Pp 331-342 (2001)
Many cases of early-onset inherited Alzheimer's disease (AD) are caused by mutations in the presenilin-1 (PS1) gene. Expression of PS1 mutations in cell culture systems and in primary neurons from transgenic mice increases their vulnerability to cell
Externí odkaz:
https://doaj.org/article/a997bd3402fe4b9b91e6a231ee2cdc38
Publikováno v:
Neuromolecular Medicine
Synaptic impairment may be the main cause of cognitive dysfunction in brain aging that is probably due to a reduction in synaptic contact between the axonal buttons and dendritic spines. Rho proteins including the small GTPase Rac1 have become key re
Autor:
Talar Hopyan, Anna Wacker, Sandra Schläfke, Walter E. Müller, Hans-Peter Volz, Hans-Jürgen Möller, Erich Seifritz, Siegfried Kasper
Publikováno v:
International Journal of Neuropsychopharmacology
Background Silexan is a lavender essential oil with established anxiolytic and calming efficacy. Here we asked whether there is a potential for abuse in human patients. Methods We carried out a phase I abuse liability single-center, double-blind, 5-w
Publikováno v:
Mueller, J K, Riederer, P & Müller, W E 2022, ' Neuropsychiatric Drugs Against COVID-19 : What is the Clinical Evidence? ', Pharmacopsychiatry, vol. 55, no. 1, pp. 7-15 . https://doi.org/10.1055/a-1717-2381
Since the beginning of the coronavirus disease (COVID)-19 pandemic, the need for effective treatments for COVID-19 led to the idea of “repurposing” drugs for antiviral treatment. Several antipsychotics and antidepressants have been tested for in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50b4d249d37a799af85454f4ea622ba0
https://portal.findresearcher.sdu.dk/da/publications/a5a2fa64-b49c-471c-b3bc-c667e70c2532
https://portal.findresearcher.sdu.dk/da/publications/a5a2fa64-b49c-471c-b3bc-c667e70c2532
Publikováno v:
NeuroPsychopharmacotherapy ISBN: 9783030620585
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::23e67190cc04f915f61863c6e7e67c61
https://doi.org/10.1007/978-3-030-62059-2_192
https://doi.org/10.1007/978-3-030-62059-2_192