Zobrazeno 1 - 10
of 66
pro vyhledávání: '"Walter E. Laug"'
Autor:
Maya Otto-Duessel, Vazgen Khankaldyyan, Ignacio Gonzalez-Gomez, Michael C. Jensen, Walter E. Laug, Michael Rosol
Publikováno v:
Molecular Imaging, Vol 5 (2006)
In vivo bioluminescent imaging using cells expressing Renilla luciferase is becoming increasingly common. Hindrances to the more widespread use of Renilla luciferase are the high autoluminescence of its natural substrate, coelenterazine, in plasma; t
Externí odkaz:
https://doaj.org/article/d3c1261b06ec43889313bac59b64cadf
Autor:
Rex A. Moats, Sendhil Velan-Mullan, Russell Jacobs, Ignacio Gonzalez-Gomez, David J. Dubowitz, Takashi Taga, Vazgen Khankaldyyan, Linda Schultz, Scott Fraser, Marvin D. Nelson, Walter E. Laug
Publikováno v:
Molecular Imaging, Vol 2 (2003)
In vivo imaging methodologies allow for serial measurement of tumor size, circumventing the need for sacrificing mice at given time points. In orthotopically transplanted murine models of brain tumors, cross-section micro-MRI allows for visualization
Externí odkaz:
https://doaj.org/article/7f35d036b5794e00995a2eac55ea78b1
Autor:
Agnès Noël, Yves A. DeClerck, Khalid Bajou, Joseph A. Martial, Hongjun Peng, Walter E. Laug, J.-M. Foidart, Catherine Maillard
Publikováno v:
Cancer Cell. 14:324-334
SUMMARY Plasminogen activator inhibitor-1 (PAI-1) paradoxically enhances tumor progression and angiogenesis; however, the mechanism supporting this role is not known. Here we provide evidence that PAI-1 is essential to protect endothelial cells (ECs)
A Non-invasive, in Vivo Technique for Monitoring Vascular Status of Glioblastoma during Angiogenesis
Publikováno v:
Technology in Cancer Research & Treatment. 6:641-650
The growth of solid tumors dependent on the process of angiogenesis in which growth factors secreted by tumor and stromal cells promote endothelial cell proliferation, migration, and maturation. This process generates a tumor-specific vascular supply
Publikováno v:
Physics in Medicine and Biology. 52:5295-5308
Determination of tumor oxygenation at the microvascular level will provide important insight into tumor growth, angiogenesis, necrosis and therapeutic response and will facilitate to develop protocols for studying tumor behavior. The non-ionizing nea
Autor:
Shinya Yamada, Vazgen Khankaldyyan, Xing-Yao Bu, Walter E. Laug, J. Gordon McComb, Ignacio Gonzales-Gomez
Publikováno v:
Neurosurgery. 59:1304-1312
Objective To determine the effect of the angiogenesis inhibitor Cilengitide (EMD 121974) on glioblastoma growth and associated angiogenesis in the brains of nude mice. Methods Human glioblastoma cells (10 U87MG cells) in 1 mul of medium were stereota
Autor:
Xiaoyuan Chen, Peter S. Conti, James R. Bading, Vazgen Khankaldyyan, Michel Tohme, Rex Moats, Ryan Park, Walter E. Laug, Ignacio Gonzales-Gomez
Publikováno v:
Molecular Imaging and Biology. 8:9-15
EMD 121974, a potent cyclic RGD peptide inhibitor of α v-integrins, demonstrated effectiveness in suppressing brain tumor growth in both preclinical models and phases I/II clinical trials. The ability to non-invasively evaluate α v-integrin express
Autor:
Jiang Huai Wang, Walter E. Laug, Emmet Andrews, Conor Shields, H. Paul Redmond, Desmond C. Winter
Publikováno v:
Surgery. 136:76-83
Hypertonic saline infusion dampens inflammatory responses and suppresses neutrophil-endothelial interaction by reducing adhesion molecule expression. This study tested the hypothesis that hypertonic saline attenuates tumor cell adhesion to the endoth
Autor:
Marvin D. Nelson, Michael Rosol, Walter E. Laug, Rex Moats, Vazgen Khankaldyyan, Donald B. Kohn, Javier S. Burgos
Publikováno v:
BioTechniques. 34:1184-1188
In vivo bioluminescence imaging is becoming increasingly popular. Quantification of bioluminescent signals requires knowledge of the variability and reproducibility of this technique. The objective of this study was to analyze the time course of lumi
Autor:
Tai-Lan Tuan, Diana V. Messadi, Huayang Wu, Anh Le, Sheree S. N. Chong, Paul Kelly, Walter E. Laug, Eunice Y. Huang
Publikováno v:
The American Journal of Pathology. 162:1579-1589
Proteolytic degradation of the provisional fibrin matrix and subsequent substitution by fibroblast-produced collagen are essential features of injury repair. Immunohistochemical studies revealed that although dermal fibroblasts of normal scars and ke