Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Walter D. Niles"'
Autor:
Evan Y. Snyder, Walter D. Niles
Publikováno v:
Current protocolsLiterature Cited. 1(5)
Fetal human neural stem cells (fhNSC) are of considerable interest as potential regenerative therapies for neuronal or glial degeneration or destruction resulting from genetic abnormalities, disease, or injury. Realization of this potential requires
Publikováno v:
Current Protocols in Stem Cell Biology
The normal development of the pulmonary system is critical to transitioning from placental‐dependent fetal life to alveolar‐dependent newborn life. Human lung development and disease have been difficult to study due to the lack of an in vitro mod
Autor:
Dustin R. Wakeman, Nirmalya Ghosh, Amy Plaia, Nejmi Dilmac, Walter D. Niles, Richard E. Hartman, Ruslan Nuryyev, Evan Y. Snyder, Neal H. Nathan, Melissa S. Dulcich, Alena Yusof, Richard L. Sidman, Beatriz Tone, Stephen Ashwal, Janessa B Law, Cameron D. Pernia, Andre Obenaus
Publikováno v:
Cell Reports. 31:107622
To date, no stem cell therapy has been directed to specific recipients-and, conversely, withheld from others-based on a clinical or molecular profile congruent with that cell's therapeutic mechanism-of-action (MOA) for that condition. We address this
Publikováno v:
JALA: Journal of the Association for Laboratory Automation. 15:355-361
Advances in laboratory instrumentation often increase the complexity, size, and cost of the device. The resulting complexity and cost, however, then reduce the accessibility of the device to many laboratories. We examine ways to use technological adv
Autor:
Walter D. Niles, Peter J. Coassin
Publikováno v:
ASSAY and Drug Development Technologies. 6:577-590
Extension of ultra-high-throughput experiment (UHTE) approaches to new assay methodologies is often limited by compromised data quality when samples are miniaturized. Overcoming this challenge requires attending to all components of an automated labo
Autor:
Walter D. Niles, Paul A. Jain, Lina Mastrangelo, Brian T. D. Tobe, Shreyasi Das, Alicia M. Winquist, Evan Y. Snyder
Treatment for neurological diseases or trauma remains the last frontier in modern medicine because there is no effective way to repair the central nervous system (CNS) and restore function. In this chapter, we discuss neural stem cells (NSCs) as an i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::70890e972b6d7bcb72cc2c06cee8d147
https://doi.org/10.1016/b978-0-12-410396-2.00029-3
https://doi.org/10.1016/b978-0-12-410396-2.00029-3
Autor:
Hiroyuki Osada, Hongwei Holly Yin, Guido J.R. Zaman, C. David Weaver, Thomas Lundbäck, Andrew D. Napper, Walter D. Niles, J. Fraser Glickman, Anton Simeonov
Publikováno v:
Assay and drug development technologies. 12(8)
Has the impact of irreproducibility on the discovery and development of drugs, as with global warming, metaphorically speaking, crept up on us as we slept? Or is the problem more an issue of heightened awareness? We currently find ourselves in a time
Autor:
Aaron K. Wong, Valentina Goncharova, Sophia Khaldoyanidi, Shreyasi Das, Dustin R. Wakeman, Leonard Miller, Walter D. Niles, Evan Y. Snyder, Tatiana Povaly, Ingrid U. Schraufstatter
Human neural stem cells (hNSCs) hold great potential for treatment of a wide variety of neurodegenerative and neurotraumatic conditions. Heretofore, administration has been through intracranial injection or implantation of cells. Because neural stem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5bded5171117214a5b5ddc708658ab27
https://europepmc.org/articles/PMC3925049/
https://europepmc.org/articles/PMC3925049/
Autor:
Richard D. Minshall, Joseph E. Parrillo, Asrar B. Malik, Steven M. Hollenberg, Cordus R. Easington, Stephen M. Vogel, Walter D. Niles, Chinnaswamy Tiruppathi
Publikováno v:
Microvascular Research. 61:87-101
We used video fluorescence microscopy of the vascular bed in the cremaster muscle of rat and mouse to study the transfer of plasmalemma vesicles (caveolae) across the microvessel barrier in situ. The water-soluble styryl pyridinium dye RH414, which a
Autor:
Asrar B. Malik, Richard D. Minshall, Heidi E. Hamm, Annette Gilchrist, Chinnaswamy Tiruppathi, Walter D. Niles, Stephen M. Vogel
Publikováno v:
The Journal of Cell Biology
We tested the hypothesis that the albumin-docking protein gp60, which is localized in caveolae, couples to the heterotrimeric GTP binding protein G(i), and thereby activates plasmalemmal vesicle formation and the directed migration of vesicles in end