Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Walter A. Prütz"'
Autor:
Walter A. Prütz
Publikováno v:
Archives of Biochemistry and Biophysics. 371:107-114
Cyclic dipeptides (c-Gly 2 , c-Ser 2 , c-Gly-Phe, etc.) were used as simple protein models to investigate the HOCl-induced generation and reactivity of chlorinated amide groups. The pH dependence of the kinetics of amide chlorination reveals that ClO
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c2b64f342f98e06553e00696a71cf82
https://doi.org/10.1006/abbi.1999.1377
https://doi.org/10.1006/abbi.1999.1377
Autor:
Walter A. Prütz
Publikováno v:
Archives of Biochemistry and Biophysics. 357:265-273
The activation of reactions of HOCl with a variety of model substrates by tertiary amines was investigated spectroscopically by tandem-mix and stopped-flow techniques. HOCl-induced chlorination of salicylate can be sped up by several orders of magnit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4018f97cbbe5a888dd6760a6ff8e201
https://doi.org/10.1006/abbi.1998.0822
https://doi.org/10.1006/abbi.1998.0822
Autor:
Walter A. Prütz
Publikováno v:
Archives of Biochemistry and Biophysics. 349:183-191
HOCl-induced chlorination of pyrimidine nucleotides, PyNH, strikingly depends on the nature of the available chlorine acceptor group. For CMP, with an −NH 2 group as acceptor, the reaction is slow and involves predominantly the acid [ k (CMP + HOCl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d993b982926aeb9486a75e1357e6688
https://doi.org/10.1006/abbi.1997.0440
https://doi.org/10.1006/abbi.1997.0440
Autor:
Walter A. Prütz
Publikováno v:
Archives of Biochemistry and Biophysics. 332:110-120
HOC1-induced one-electron oxidation of Fe(CN)(6)4- was used as a reference reaction to investigate the stoichiometry of interaction of HOCl with a variety of biological substrates. GSH and GSSG were both found capable of reacting with four and 2-merc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abae0b6475925ee07dba3548584dbcba
https://doi.org/10.1006/abbi.1996.0322
https://doi.org/10.1006/abbi.1996.0322
Autor:
Walter A. Prütz
Publikováno v:
Journal of Biochemical and Biophysical Methods. 32:125-135
The ETB-binding assay provides a rapid means to investigate time profiles for oxidative degradation of double-stranded DNA, by detecting the loss of ability of DNA to form a fluorescent intercalation complex with ETB. The assay was applied to demonst
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87741f4a8f5369e987aebbc6b2381fd2
https://doi.org/10.1016/0165-022x(96)00006-1
https://doi.org/10.1016/0165-022x(96)00006-1
Autor:
Walter A. Prütz
Publikováno v:
Zeitschrift für Naturforschung C. 50:209-219
Selenite and selenocystamine [(CyaSe)2] efficiently activate the decomposition of H2O2 y GSH and by other thiols, as demonstrated using a leuco crystal violet POD-based H2O2 assay which is applicable (unlike other assays) also in presence of thiols.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c96c5ca05313e4e54f9b36fdc8510790
https://doi.org/10.1515/znc-1995-3-409
https://doi.org/10.1515/znc-1995-3-409
Publikováno v:
Biophysical Chemistry. 49:101-111
The GS.+GS− ⇌ GSS.− G equilibrium (1) was reinvestigated as a function of pH and ionic strength, using pulse radiolysis to oxidize GSH to GS.. All radicals formed by water radiolysis can be converted to populate equilibrium (1), which presents
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::83a25eb6b44fbd9a081e8191e52866ca
https://doi.org/10.1016/0301-4622(93)e0057-c
https://doi.org/10.1016/0301-4622(93)e0057-c
Autor:
Walter A. Prütz
Publikováno v:
Zeitschrift für Naturforschung C. 48:872-878
Cu(II)-Induced oxidation of catechols (dopa, dopamine and epinephrine) to yield indolic aminochromes is speeded up by at least two orders of magnitude upon addition of DNA. This effect was observed both in aerobic and anaerobic solutions, indicating
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::35668c48c67ed252e9b851bcfd68e52a
https://doi.org/10.1515/znc-1993-11-1210
https://doi.org/10.1515/znc-1993-11-1210
Publikováno v:
ResearcherID
Oxidation of cytochrome c, a key protein in mitochondrial electron transport and a mediator of apoptotic cell death, by reactive halogen species (HOX, X2), i.e., metabolites of activated neutrophils, was investigated by stopped-flow. The fast initial
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::499b556a8ba9ef3259744bc56837a95c
https://pubmed.ncbi.nlm.nih.gov/11370661
https://pubmed.ncbi.nlm.nih.gov/11370661
Publikováno v:
ResearcherID
Degradation of the reduced pyridine nucleotides NMNH and NADH by HOCl involves two distinct stages: a fast reaction, k = 4.2 x 10(5) M(-1) s(-1), leads to generation of stable pyridine products (Py/Cl) with a strong absorption band at 275 nm (epsilon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4beea5bfe36e1753a098dc1a3f2c7e70
https://pubmed.ncbi.nlm.nih.gov/10900148
https://pubmed.ncbi.nlm.nih.gov/10900148