Zobrazeno 1 - 10
of 424
pro vyhledávání: '"Walter A Koltun"'
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
BackgroundThe incidence of colorectal cancer (CRC) has been steadily increasing in younger individuals over the past several decades for reasons that are incompletely defined. Identifying differences in gene expression profiles, or transcriptomes, in
Externí odkaz:
https://doaj.org/article/d3d7cbfd3bb3484495bd930968fafa69
Autor:
Francisco Arroyo Almenas, Gábor Törő, Peter Szaniszlo, Manjit Maskey, Ketan K. Thanki, Walter A. Koltun, Gregory S. Yochum, Irina V. Pinchuk, Celia Chao, Mark R. Hellmich, Katalin Módis
Publikováno v:
Antioxidants, Vol 13, Iss 9, p 1067 (2024)
Cystathionine gamma-lyase (CSE) and TNF-α are now recognized as key regulators of intestinal homeostasis, inflammation, and wound healing. In colonic epithelial cells, both molecules have been shown to influence a variety of biological processes, bu
Externí odkaz:
https://doaj.org/article/7455c9bd5d034ec49d339a6ccd807eb1
Autor:
Trayambak Pathak, Maxime Gueguinou, Vonn Walter, Celine Delierneux, Martin T Johnson, Xuexin Zhang, Ping Xin, Ryan E Yoast, Scott M Emrich, Gregory S Yochum, Israel Sekler, Walter A Koltun, Donald L Gill, Nadine Hempel, Mohamed Trebak
Publikováno v:
eLife, Vol 12 (2023)
Externí odkaz:
https://doaj.org/article/bacfc4e9fb7f4dd8bf3716d520a39baf
Autor:
Olivia M. Marx, Marc M. Mankarious, Melanie A. Eshelman, Wei Ding, Walter A. Koltun, Gregory S. Yochum
Publikováno v:
Biomolecules, Vol 12, Iss 9, p 1223 (2022)
Despite a global decrease in colorectal cancer (CRC) incidence, the prevalence of early-onset colorectal cancer (EOCRC), or those occurring in individuals before the age of 50, has steadily increased over the past several decades. When compared to la
Externí odkaz:
https://doaj.org/article/3b72e533a9a5400990d33be42b34f3f7
Autor:
Austin C. Portolese, Brittney N. McMullen, Samantha K. Baker, Jeremy R. Chen See, Gregory S. Yochum, Walter A. Koltun, Regina Lamendella, Nimalan A. Jeganathan
Publikováno v:
Diseases of the Colon & Rectum. 66:707-715
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3a4937cd56a6857e7eafe58ce484fa29
https://doi.org/10.1097/dcr.0000000000002647
https://doi.org/10.1097/dcr.0000000000002647
Autor:
Xiaojing Zhao, Wenjing Yang, Tianming Yu, Yu Yu, Xiufang Cui, Zheng Zhou, Hui Yang, Yanbo Yu, Anthony J. Bilotta, Suxia Yao, Jimin Xu, Jia Zhou, Gregory S. Yochum, Walter A. Koltun, Austin Portolese, Defu Zeng, Jingwu Xie, Iryna V. Pinchuk, Hongjie Zhang, Yingzi Cong
Publikováno v:
Gastroenterology. 164:89-102
Intestinal fibrosis is a significant complication of Crohn's disease (CD). Gut microbiota reactive Th17 cells are crucial in the pathogenesis of CD; however, how Th17 cells induce intestinal fibrosis is still not completely understood.In this study,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::922b87aadd2a20d695dfa91e332d6a61
https://doi.org/10.1053/j.gastro.2022.09.006
https://doi.org/10.1053/j.gastro.2022.09.006
Autor:
Trayambak Pathak, Maxime Gueguinou, Vonn Walter, Celine Delierneux, Martin T Johnson, Xuexin Zhang, Ping Xin, Ryan E Yoast, Scott M Emrich, Gregory S Yochum, Israel Sekler, Walter A Koltun, Donald L Gill, Nadine Hempel, Mohamed Trebak
Publikováno v:
eLife, Vol 9 (2020)
Despite the established role of mitochondria in cancer, the mechanisms by which mitochondrial Ca2+ (mtCa2+) regulates tumorigenesis remain incompletely understood. The crucial role of mtCa2+ in tumorigenesis is highlighted by altered expression of pr
Externí odkaz:
https://doaj.org/article/5281232761db416a876d72cbe79942a1
Autor:
Kathleen M. Schieffer, Kate Sabey, Justin R. Wright, David R. Toole, Rebecca Drucker, Vasily Tokarev, Leonard R. Harris, Sue Deiling, Melanie A. Eshelman, John P. Hegarty, Gregory S. Yochum, Walter A. Koltun, Regina Lamendella, David B. Stewart
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-10 (2017)
Abstract Diverticular disease is commonly associated with the older population in the United States. As individual’s age, diverticulae, or herniation of the mucosa through the colonic wall, develop. In 10–25% of individuals, the diverticulae beco
Externí odkaz:
https://doaj.org/article/e273bd9a791641cebe6167e50d07869e
Autor:
Eugene Gonzalez-Lopez, Yuka Kawasawa-Imamura, Lijun Zhang, Xuemei Huang, Walter A Koltun, Matthew D Coates, Kent E Vrana
Publikováno v:
PLoS ONE, Vol 14, Iss 2, p e0210175 (2019)
Inflammatory bowel diseases (IBD) are associated with altered neuronal regulation of the gastrointestinal (GI) tract and release of norepinephrine (NE). As sympathetic innervation of the GI tract modulates motility, blood flow, and immune function, c
Externí odkaz:
https://doaj.org/article/f95bfc4fb9664126969af3339a66ad80
Publikováno v:
PLoS ONE, Vol 14, Iss 2, p e0212850 (2019)
Crohn's disease (CD) is a debilitating inflammatory bowel disease (IBD) that arises from chronic inflammation in the gastrointestinal tract. Genome-wide association studies (GWAS) have identified over 200 single nucleotide polymorphisms (SNPs) that a
Externí odkaz:
https://doaj.org/article/ec3bc7ec53624938b2cc9a5c5966c243