Zobrazeno 1 - 10
of 600
pro vyhledávání: '"Walter Berger"'
Autor:
Aude Ingels, Robert Scott, Annie R. Hooper, Aletta E. van der Westhuyzen, Sachin B. Wagh, Joséphine de Meester, Lucia Maddau, Doris Marko, Georg Aichinger, Walter Berger, Marjorie Vermeersch, David Pérez-Morga, Vladimir A. Maslivetc, Antonio Evidente, Willem A. L. van Otterlo, Alexander Kornienko, Véronique Mathieu
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-18 (2024)
Abstract Sphaeropsidins are iso-pimarane diterpenes produced by phytopathogenic fungi that display promising anticancer activities. Sphaeropsidin A, in particular, has been shown to counteract regulatory volume increase, a process used by cancer cell
Externí odkaz:
https://doaj.org/article/6c21a3354a474dd69508d75741c9d1ba
Autor:
Karin Schelch, Sebastian Eder, Benjamin Zitta, Monica Phimmachanh, Thomas G. Johnson, Dominik Emminger, Andrea Wenninger‐Weinzierl, Caterina Sturtzel, Hugo Poplimont, Alexander Ries, Konrad Hoetzenecker, Mir A. Hoda, Walter Berger, Martin Distel, Balazs Dome, Glen Reid, Michael Grusch
Publikováno v:
Molecular Oncology, Vol 18, Iss 4, Pp 815-831 (2024)
Pleural mesothelioma (PM) is characterized by rapid growth, local invasion, and limited therapeutic options. The multifunctional oncoprotein Y‐box‐binding protein‐1 (YB‐1) is frequently overexpressed in cancer and its inhibition reduces aggre
Externí odkaz:
https://doaj.org/article/0fdbc05b2f2540f8bfe43842f519eeb5
Autor:
Livia Gruber, Maximilian Jobst, Endre Kiss, Martina Karasová, Bernhard Englinger, Walter Berger, Giorgia Del Favero
Publikováno v:
Cell Communication and Signaling, Vol 21, Iss 1, Pp 1-21 (2023)
Abstract Bladder cells face a challenging biophysical environment: mechanical cues originating from urine flow and regular contraction to enable the filling voiding of the organ. To ensure functional adaption, bladder cells rely on high biomechanical
Externí odkaz:
https://doaj.org/article/83e91a88af9b4691907dee2f54a6cd0b
Autor:
Berta Mosleh, Karin Schelch, Thomas Mohr, Thomas Klikovits, Christina Wagner, Lukas Ratzinger, Yawen Dong, Katharina Sinn, Alexander Ries, Walter Berger, Bettina Grasl‐Kraupp, Konrad Hoetzenecker, Viktoria Laszlo, Balazs Dome, Balazs Hegedus, Marko Jakopovic, Mir Alireza Hoda, Michael Grusch
Publikováno v:
Thoracic Cancer, Vol 14, Iss 22, Pp 2177-2186 (2023)
Abstract Background Pleural mesothelioma (PM) is a relatively rare malignancy with limited treatment options and dismal prognosis. We have previously found elevated FGF18 expression in PM tissue specimens compared with normal mesothelium. The objecti
Externí odkaz:
https://doaj.org/article/280b1a46403a482d865fcc37356d2cba
Autor:
Cornelia Schmutz, Crepelle Plaza, Franziska Steiger, Natascha Stoirer, Judith Gufler, Gudrun Pahlke, Frank Will, Walter Berger, Doris Marko
Publikováno v:
Antioxidants, Vol 13, Iss 7, p 846 (2024)
Chemotherapy with irinotecan (CPT-11), the pro-drug of the highly cytotoxic SN-38, is among the standard-of-care treatments for colorectal cancer. To counteract undesired toxic side effects on healthy tissue such as the intestinal epithelium, the use
Externí odkaz:
https://doaj.org/article/1fdb495ddafb4679881d27b1d7c34cf2
Autor:
Dina Baier, Theresa Mendrina, Beatrix Schoenhacker‐Alte, Christine Pirker, Thomas Mohr, Mate Rusz, Benedict Regner, Martin Schaier, Nicolas Sgarioto, Noël J.‐M. Raynal, Karin Nowikovsky, Wolfgang M. Schmidt, Petra Heffeter, Samuel M. Meier‐Menches, Gunda Koellensperger, Bernhard K. Keppler, Walter Berger
Publikováno v:
Advanced Science, Vol 10, Iss 32, Pp n/a-n/a (2023)
Abstract The leading first‐in‐class ruthenium‐complex BOLD‐100 currently undergoes clinical phase‐II anticancer evaluation. Recently, BOLD‐100 is identified as anti‐Warburg compound. The present study shows that also deregulated lipid m
Externí odkaz:
https://doaj.org/article/574893a0a400479184a02dd6ac444ed6
Autor:
Jasmin Taubenschmid‐Stowers, Michael Orthofer, Anna Laemmerer, Christian Krauditsch, Marianna Rózsová, Christian Studer, Daniela Lötsch, Johannes Gojo, Lisa Gabler, Matheus Dyczynski, Thomas Efferth, Astrid Hagelkruys, Georg Widhalm, Andreas Peyrl, Sabine Spiegl‐Kreinecker, Dominic Hoepfner, Shan Bian, Walter Berger, Juergen A Knoblich, Ulrich Elling, Moritz Horn, Josef M Penninger
Publikováno v:
EMBO Molecular Medicine, Vol 15, Iss 3, Pp 1-20 (2023)
Abstract The natural compound Artemisinin is the most widely used antimalarial drug worldwide. Based on its cytotoxicity, it is also used for anticancer therapy. Artemisinin and its derivates are endoperoxides that damage proteins in eukaryotic cells
Externí odkaz:
https://doaj.org/article/7735106cb6194b64bd51f140f2fd01c5
Autor:
Alexander Ries, Daniela Flehberger, Astrid Slany, Christine Pirker, Johanna C. Mader, Thomas Mohr, Karin Schelch, Katharina Sinn, Berta Mosleh, Mir Alireza Hoda, Balazs Dome, Helmut Dolznig, Georg Krupitza, Leonhard Müllauer, Christopher Gerner, Walter Berger, Michael Grusch
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 42, Iss 1, Pp 1-20 (2023)
Abstract Background Pleural mesothelioma (PM) is an aggressive malignancy with poor prognosis. Unlike many other cancers, PM is mostly characterized by inactivation of tumor suppressor genes. Its highly malignant nature in absence of tumor driving on
Externí odkaz:
https://doaj.org/article/0584feb1baa7455e98b30e32f6b10aef
Autor:
Helena Sorger, Saptaswa Dey, Pablo Augusto Vieyra‐Garcia, Daniel Pölöske, Andrea R Teufelberger, Elvin D de Araujo, Abootaleb Sedighi, Ricarda Graf, Benjamin Spiegl, Isaac Lazzeri, Till Braun, Ines Garces de los Fayos Alonso, Michaela Schlederer, Gerald Timelthaler, Petra Kodajova, Christine Pirker, Marta Surbek, Michael Machtinger, Thomas Graier, Isabella Perchthaler, Yi Pan, Regina Fink‐Puches, Lorenzo Cerroni, Jennifer Ober, Moritz Otte, Jana D Albrecht, Gary Tin, Ayah Abdeldayem, Pimyupa Manaswiyoungkul, Olasunkanmi O Olaoye, Martin L Metzelder, Anna Orlova, Walter Berger, Marion Wobser, Jan P Nicolay, Fiona André, Van Anh Nguyen, Heidi A Neubauer, Roman Fleck, Olaf Merkel, Marco Herling, Ellen Heitzer, Patrick T Gunning, Lukas Kenner, Richard Moriggl, Peter Wolf
Publikováno v:
EMBO Molecular Medicine, Vol 14, Iss 12, Pp 1-23 (2022)
Abstract Leukemic cutaneous T‐cell lymphomas (L‐CTCL) are lymphoproliferative disorders of skin‐homing mature T‐cells causing severe symptoms and high mortality through chronic inflammation, tissue destruction, and serious infections. Despite
Externí odkaz:
https://doaj.org/article/c1ee8bac3c164d9b80fc189cf3bc69bf
Autor:
Cornelia Schmutz, Frank Will, Elisabeth Varga, Carola Jaunecker, Gudrun Pahlke, Walter Berger, Doris Marko
Publikováno v:
Molecules, Vol 28, Iss 23, p 7684 (2023)
Anti-oxidant, -inflammatory, and -carcinogenic activities of bioactive plant constituents, such as anthocyanins, have been widely discussed in literature. However, the potential interaction of anthocyanin-rich extracts with routinely used chemotherap
Externí odkaz:
https://doaj.org/article/5730dcdace5c4c2da9c17c6f606dfdad