Zobrazeno 1 - 10
of 355
pro vyhledávání: '"Walter, Jeske"'
Autor:
Fakiha Siddiqui BDS, Debra Hoppensteadt PhD, Walter Jeske PhD, Eduardo Ramacciotti MD, PhD, Alfonso Tafur MD, MS, MBA, Jawed Fareed PhD, FAHA
Publikováno v:
Clinical and Applied Thrombosis/Hemostasis, Vol 30 (2024)
Introduction Andexanet alfa (AA) - zhzo, recombinant coagulation factor Xa, is an approved antidote for oral Xa inhibitors (apixaban and rivaroxaban). Unfractionated heparin (UFH) is commonly used for therapeutic, interventional, and surgical indicat
Externí odkaz:
https://doaj.org/article/b626561e959842a89b3955e3da6842d6
Autor:
Guy Olson BS, Walter Jeske PhD, Omer Iqbal MD, Emily Krupa BS, Amber Farooqui MD, Fakiha Siddiqui BDS, Debra Hoppensteadt PhD, Ahmed Kouta PhD, Jawed Fareed PhD
Publikováno v:
Clinical and Applied Thrombosis/Hemostasis, Vol 29 (2023)
Introduction: Bovine and ovine mucosa represent alternate anticoagulants to porcine mucosa for production of unfractionated heparin (UFH). Standardized heparins from various sources can be blended and potency adjusted, blended heparins exhibit compar
Externí odkaz:
https://doaj.org/article/a22e14aa5cf148389f9dbf9a742d529d
Autor:
Siddharth Mehrotra, Debra Hoppensteadt PhD, Walter Jeske PhD, Fakiha Siddiqui BS, Omer Iqbal MD, Alfonso Tafur MD, Bruce Lewis MD, Mark Jaradeh BS, Bulent Kantarcioglu MD, Jawed Fareed PhD
Publikováno v:
Clinical and Applied Thrombosis/Hemostasis, Vol 28 (2022)
Introduction The available oral anti-Xa agents are routinely used for the management of thrombotic disorders. A molecularly modified recombinant coagulation FXa, also known as Andexanet Alfa (AA), that has been developed as an antidote to neutralize
Externí odkaz:
https://doaj.org/article/ea1b4598519b4811bd1e31d03d5eacd1
Autor:
Bulent Kantarcioglu MD, Amir Darki MD, MSc, Fakiha Siddiqui BDS, Emily Krupa BS, Mehmet Vural MD, Murat Kacmaz MD, Debra Hoppensteadt PhD, Omer Iqbal MD, Walter Jeske PhD, Jeanine Walenga PhD, Cafer Adiguzel MD, Jawed Fareed PhD
Publikováno v:
Clinical and Applied Thrombosis/Hemostasis, Vol 28 (2022)
Introduction In this study, we profiled the levels of blood cellular indices, endogenous glycosaminoglycans (GAGs) and inflammatory biomarkers in a cohort comprised of pulmonary embolism (PE) patients, to determine their inter-relationships. Identifi
Externí odkaz:
https://doaj.org/article/110980c3dd7e456e97b9d9aa585a6b9c
Autor:
Joseph Lewis BA, Omer Iqbal MD, Walter Jeske PhD, Debra Hoppensteadt PhD, Fakiha Siddiqui BDS, Jawed Fareed PhD
Publikováno v:
Clinical and Applied Thrombosis/Hemostasis, Vol 28 (2022)
Introduction Andexanet alfa (andexanet) is an approved antidote used to reverse the bleeding effects of Direct Oral Anticoagulant (Direct-Xa agents) agents because it reverses anti-Xa activity. Unfractionated heparin (UFH) and low molecular weight he
Externí odkaz:
https://doaj.org/article/898573021cb94fc8992380467d649964
Autor:
Bulent Kantarcioglu MD, Omer Iqbal MD, Joseph Lewis BA, Charles A. Carter BS, PharmD, MBA, Meharvan Singh PhD, Fabio Lievano MD, Mark Ligocki DDS, Walter Jeske PhD, Cafer Adiguzel MD, Grigoris T. Gerotziafas MD, Jawed Fareed PhD
Publikováno v:
Clinical and Applied Thrombosis/Hemostasis, Vol 28 (2022)
The progress in the development of various vaccine platforms against SARS-CoV-2 have been rather remarkable owing to advancement in molecular and biologic sciences. Most of the current vaccines and those in development focus on targeting the viral sp
Externí odkaz:
https://doaj.org/article/741f56f93ee449b996396bf179e8415d
Autor:
Yash Gupta, Neha Sharma, Snigdha Singh, Jesus G. Romero, Vinoth Rajendran, Reagan M. Mogire, Mohammad Kashif, Jordan Beach, Walter Jeske, Poonam, Bernhards R. Ogutu, Stefan M. Kanzok, Hoseah M. Akala, Jennifer Legac, Philip J. Rosenthal, David J. Rademacher, Ravi Durvasula, Agam P. Singh, Brijesh Rathi, Prakasha Kempaiah
Publikováno v:
Pharmaceutics, Vol 14, Iss 7, p 1371 (2022)
Malaria elimination urgently needs novel antimalarial therapies that transcend resistance, toxicity, and high costs. Our multicentric international collaborative team focuses on developing multistage antimalarials that exhibit novel mechanisms of act
Externí odkaz:
https://doaj.org/article/51f533a3d8a647a8b2b71052ec3441fa
Autor:
Bulent Kantarcioglu MD, Omer Iqbal MD, Jeanine M. Walenga PhD, Bruce Lewis MD, Joseph Lewis BS, Charles A. Carter BS, PharmD, MBA, Meharvan Singh PhD, Fabio Lievano MD, Alfonso Tafur MD, Eduardo Ramacciotti MD, PhD, Grigoris T. Gerotziafas MD, Walter Jeske PhD, Jawed Fareed PhD
Publikováno v:
Clinical and Applied Thrombosis/Hemostasis, Vol 27 (2021)
Today the coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), has become a global health problem. After more than a year with the pandemic, although our knowledge has progressed on COVID-19, th
Externí odkaz:
https://doaj.org/article/3d9997940c8a4576badc74267608d342
Autor:
Ahmed Kouta MS, MBA, Walter Jeske PhD, Lee Cera DVM, PhD, Azarfrooz Farshid DVM, Richard Duff BS, CVT (AVMA), Debra Hoppensteadt PhD, Jawed Fareed PhD
Publikováno v:
Clinical and Applied Thrombosis/Hemostasis, Vol 27 (2021)
Introduction: Currently used unfractionated heparins (UFHs) and low molecular weight heparins (LMWHs) are derived from porcine intestinal mucosa. However, heparins have also been manufactured from tissues of other mammalian species such as cow (Bovin
Externí odkaz:
https://doaj.org/article/399a6b4855734fd28e5d0f8bd048ffb6
Autor:
Ahmed Kouta MS, MBA, Debra Hoppensteadt PhD, Emily Bontekoe BSc, Walter Jeske PhD, Richard Duff BS, CVT (AVMA), Lee Cera DVM, PhD, Jawed Fareed PhD
Publikováno v:
Clinical and Applied Thrombosis/Hemostasis, Vol 26 (2020)
Unfractionated heparin (UFH) is a sulfated glycosaminoglycan that consists of repeating disaccharides, containing iduronic acid (or glucuronic acid) and glucosamine, exhibiting variable degrees of sulfation. UFHs release tissue factor pathway inhibit
Externí odkaz:
https://doaj.org/article/d57657fbc5614bc8819d05ec4159fc29