Zobrazeno 1 - 10
of 89
pro vyhledávání: '"Walter, Bodmer"'
Autor:
Edmund Gilbert, Heather Zurel, Margaret E. MacMillan, Sedat Demiriz, Sadra Mirhendi, Michael Merrigan, Seamus O’Reilly, Anne M. Molloy, Lawrence C. Brody, Walter Bodmer, Richard A. Leach, Roderick E. M. Scott, Gerald Mugford, Ranjit Randhawa, J. Claiborne Stephens, Alison L. Symington, Gianpiero L. Cavalleri, Michael S. Phillips
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-12 (2023)
Abstract The founder population of Newfoundland and Labrador (NL) is a unique genetic resource, in part due to its geographic and cultural isolation, where historical records describe a migration of European settlers, primarily from Ireland and Engla
Externí odkaz:
https://doaj.org/article/2c3ccb82bc0641ba833b58335d3b8326
Autor:
Xin Li, Robert Berahovich, Hua Zhou, Xianghong Liu, Feng Li, Shirley Xu, Yuehua Wei, Djamila Ouaret, Walter Bodmer, Lijun Wu, Vita Golubovskaya
Publikováno v:
Frontiers in Bioscience-Landmark, Vol 25, Iss 9, Pp 1765-1786 (2020)
Placental alkaline phosphatase, PLAP encoded by ALPP gene in humans is mainly expressed in placenta and testis, and not expressed in any other normal tissues. PLAP is overexpressed in colorectal cancers which makes it an attractive target for CAR (ch
Externí odkaz:
https://doaj.org/article/5bfdc71ff5d94eb9bc0e7c838cc4f713
Autor:
Qing Sun, Larry Pastor, Jinwei Du, Michael J Powell, Aiguo Zhang, Walter Bodmer, Jianzhong Wu, Shu Zheng, Michael Y Sha
Publikováno v:
PLoS ONE, Vol 16, Iss 10, p e0244332 (2021)
BackgroundColorectal cancer (CRC) is one of the leading causes of cancer-related death. Early detection is critical to reduce CRC morbidity and mortality. In order to meet this need, we developed a molecular clamping assay called the ColoScape TM ass
Externí odkaz:
https://doaj.org/article/6bc54573175a459991b18a9f502219dd
Autor:
Walter Bodmer
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Ruggero Ceppellini, who died at the age of 71 in 1988, was one of the most stimulating and original human geneticists of his generation (1). Ceppellini's outstanding contributions to the genetics of the human blood groups, immunoglobulin allotypes an
Externí odkaz:
https://doaj.org/article/1fa95801000b47e68796149a3683647b
Autor:
Shazia Irshad, Shamir Montazid, Daniel Hart, Sheila Bandyopadhyay, Brian Johnson, Sri Thrumurthy, Nan Gao, Mukesh Bansal, Philipp Altrock, Fabian Rost, Dustin Penn, Bettina Wernisch, Patrycja Gazinska, Piotr Ziółkowski, Bu'Hussain Hayee, Annamaria Tessitore, Walter Bodmer, James East, Nigel Bennett, Ian Tomlinson
The naked mole rat (NMR), Heterocephalus glaber, the longest-living rodent1, provides a unique opportunity to explore how evolution has shaped adult stem cell (ASC) activity with increasing lifespan. Using cumulative BrdU labelling and a quantitative
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c44c23da3b493211df4583495f654f06
https://doi.org/10.21203/rs.3.rs-2674841/v1
https://doi.org/10.21203/rs.3.rs-2674841/v1
Autor:
Pablo Umaña, Christian Klein, Vaios Karanikas, Jose Saro, Christiane Jaeger, Thomas von Hirschheydt, Sebastian Neumann, Sherri Dudal, Nathalie Steinhoff, Valeria Nicolini, Mario Perro, Christian Gerdes, Annette Seidl, Teilo Schaller, Sandra Grau-Richards, Peter Bruenker, Oliver Ast, Ekkehard Moessner, Ralf J. Hosse, Thomas Hofer, Steffi Lehmann, Walter Bodmer, Djamila Ouaret, Tina Weinzierl, Sara Colombetti, Johannes Sam, Tanja Fauti, Marina Bacac
Detection of tumor targeting by in vivo imaging (fluorescent intensity, FLI)of CEA TCB formats having bivalent or monovalent binding to CEA and directly labeled with Alexa647.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33aea86674eed2f9cd13b3a19897570e
https://doi.org/10.1158/1078-0432.22456469
https://doi.org/10.1158/1078-0432.22456469
Autor:
Pablo Umaña, Christian Klein, Vaios Karanikas, Jose Saro, Christiane Jaeger, Thomas von Hirschheydt, Sebastian Neumann, Sherri Dudal, Nathalie Steinhoff, Valeria Nicolini, Mario Perro, Christian Gerdes, Annette Seidl, Teilo Schaller, Sandra Grau-Richards, Peter Bruenker, Oliver Ast, Ekkehard Moessner, Ralf J. Hosse, Thomas Hofer, Steffi Lehmann, Walter Bodmer, Djamila Ouaret, Tina Weinzierl, Sara Colombetti, Johannes Sam, Tanja Fauti, Marina Bacac
Pharmacokinetic profiles of CEA TCB in mice, additional information on CD3 signaling, T cell activation, tumor cell lysis and cytokine release upon CEA TCB and untargeted control TCB treatment.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d25ab83b90dec4d79470db61b3ea72f
https://doi.org/10.1158/1078-0432.22456472
https://doi.org/10.1158/1078-0432.22456472
Autor:
Pablo Umaña, Christian Klein, Vaios Karanikas, Jose Saro, Christiane Jaeger, Thomas von Hirschheydt, Sebastian Neumann, Sherri Dudal, Nathalie Steinhoff, Valeria Nicolini, Mario Perro, Christian Gerdes, Annette Seidl, Teilo Schaller, Sandra Grau-Richards, Peter Bruenker, Oliver Ast, Ekkehard Moessner, Ralf J. Hosse, Thomas Hofer, Steffi Lehmann, Walter Bodmer, Djamila Ouaret, Tina Weinzierl, Sara Colombetti, Johannes Sam, Tanja Fauti, Marina Bacac
Purpose: CEA TCB is a novel IgG-based T-cell bispecific (TCB) antibody for the treatment of CEA-expressing solid tumors currently in phase I clinical trials (NCT02324257). Its format incorporates bivalent binding to CEA, a head-to-tail fusion of CEA-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2428e20738f737283a333f7135109820
https://doi.org/10.1158/1078-0432.c.6523319.v1
https://doi.org/10.1158/1078-0432.c.6523319.v1
Autor:
Pablo Umaña, Christian Klein, Vaios Karanikas, Jose Saro, Christiane Jaeger, Thomas von Hirschheydt, Sebastian Neumann, Sherri Dudal, Nathalie Steinhoff, Valeria Nicolini, Mario Perro, Christian Gerdes, Annette Seidl, Teilo Schaller, Sandra Grau-Richards, Peter Bruenker, Oliver Ast, Ekkehard Moessner, Ralf J. Hosse, Thomas Hofer, Steffi Lehmann, Walter Bodmer, Djamila Ouaret, Tina Weinzierl, Sara Colombetti, Johannes Sam, Tanja Fauti, Marina Bacac
Representative videos of intravital two-photon (2P) microscopy of tumors treated with CEA TCB. Tumor cells red, T cells green.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4497922bc9e17834b9280e595a0da213
https://doi.org/10.1158/1078-0432.22456454
https://doi.org/10.1158/1078-0432.22456454
Autor:
Pablo Umaña, Christian Klein, Vaios Karanikas, Jose Saro, Christiane Jaeger, Thomas von Hirschheydt, Sebastian Neumann, Sherri Dudal, Nathalie Steinhoff, Valeria Nicolini, Mario Perro, Christian Gerdes, Annette Seidl, Teilo Schaller, Sandra Grau-Richards, Peter Bruenker, Oliver Ast, Ekkehard Moessner, Ralf J. Hosse, Thomas Hofer, Steffi Lehmann, Walter Bodmer, Djamila Ouaret, Tina Weinzierl, Sara Colombetti, Johannes Sam, Tanja Fauti, Marina Bacac
Representative videos of intravital two-photon (2P) microscopy of tumors treated with untargeted TCB. Tumor cells red, T cells green.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41c8268d704f2dcda43b3c476123051d
https://doi.org/10.1158/1078-0432.22456457
https://doi.org/10.1158/1078-0432.22456457