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pro vyhledávání: '"Walt Massefski"'
Autor:
Yuzhe Xing, Walt Massefski, Manus Ipek, Ning Pan, Tam Steve Yik-Kai, Vipin Suri, Xin Xu, May Tam, James Tobin, Ying Ge, Jason Shaoyun Xiang
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 15:2865-2869
The design, synthesis, and biological evaluation of arylsulfonamidooxazoles as 11beta-HSD1 inhibitors and the serendipitous discovery of beta-keto sulfones as potent 11beta-HSD1 inhibitors are described here. These two classes of compounds are not ac