Zobrazeno 1 - 10 of 209 pro vyhledávání: '"Walsby-Tickle J"'
1
Akademický článek
Using matrix assisted laser desorption ionisation mass spectrometry combined with machine learning for vaccine authenticity screening.
Autor: Clarke R; Department of Chemistry, University of Oxford, Oxford, OX1 3TA, UK., Bharucha T; Department of Biochemistry, University of Oxford, Oxford, OX1 3QU, UK.; Kavli Institute for Nanoscience Discovery, University of Oxford, Oxford, OX1 3QU, UK., Arman BY; Department of Biochemistry, University of Oxford, Oxford, OX1 3QU, UK.; Kavli Institute for Nanoscience Discovery, University of Oxford, Oxford, OX1 3QU, UK., Gangadharan B; Department of Biochemistry, University of Oxford, Oxford, OX1 3QU, UK.; Kavli Institute for Nanoscience Discovery, University of Oxford, Oxford, OX1 3QU, UK., Gomez Fernandez L; Department of Biochemistry, University of Oxford, Oxford, OX1 3QU, UK.; Kavli Institute for Nanoscience Discovery, University of Oxford, Oxford, OX1 3QU, UK., Mosca S; Central Laser Facility, Research Complex at Harwell, STFC Rutherford Appleton Laboratory, UK Research and Innovation (UKRI), Harwell Campus, Didcot, OX11 0QX, UK., Lin Q; Central Laser Facility, Research Complex at Harwell, STFC Rutherford Appleton Laboratory, UK Research and Innovation (UKRI), Harwell Campus, Didcot, OX11 0QX, UK.; Hybrid Materials for Opto-Electronics Group, Department of Molecules and Materials, MESA+ Institute for Nanotechnology, Molecules Center and Center for Brain-Inspired Nano Systems, Faculty of Science and Technology, University of Twente, 7500AE, Enschede, the Netherlands., Van Assche K; Medicine Quality Research Group, NDM Centre for Global Health Research, Nuffield Department of Medicine, University of Oxford, Oxford, OX3 7LG, UK.; Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, 10400, Thailand.; Infectious Diseases Data Observatory, Nuffield Department of Medicine, University of Oxford, Oxford, OX3 7LG, UK., Stokes R; Agilent Technologies LDA UK, Didcot, OX11 0RA, UK., Dunachie S; Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, 10400, Thailand.; NDM Centre for Global Health Research, Nuffield Department of Medicine, University of Oxford, Oxford, OX3 7LG, UK.; NIHR Oxford Biomedical Research Centre, Oxford University Hospitals NHS Foundation Trust, Oxford, OX3 9DU, UK., Deats M; Medicine Quality Research Group, NDM Centre for Global Health Research, Nuffield Department of Medicine, University of Oxford, Oxford, OX3 7LG, UK.; Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, 10400, Thailand.; Infectious Diseases Data Observatory, Nuffield Department of Medicine, University of Oxford, Oxford, OX3 7LG, UK., Merchant HA; Department of Pharmacy, School of Applied Sciences, University of Huddersfield, Huddersfield, HD1 3DH, UK.; Department of Bioscience, School of Health, Sport and Bioscience, University of East London, Water Lane, London, E15 4LZ, UK., Caillet C; Medicine Quality Research Group, NDM Centre for Global Health Research, Nuffield Department of Medicine, University of Oxford, Oxford, OX3 7LG, UK.; Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, 10400, Thailand.; Infectious Diseases Data Observatory, Nuffield Department of Medicine, University of Oxford, Oxford, OX3 7LG, UK., Walsby-Tickle J; Department of Chemistry, University of Oxford, Oxford, OX1 3TA, UK., Probert F; Department of Chemistry, University of Oxford, Oxford, OX1 3TA, UK., Matousek P; Central Laser Facility, Research Complex at Harwell, STFC Rutherford Appleton Laboratory, UK Research and Innovation (UKRI), Harwell Campus, Didcot, OX11 0QX, UK.; Medicine Quality Research Group, NDM Centre for Global Health Research, Nuffield Department of Medicine, University of Oxford, Oxford, OX3 7LG, UK., Newton PN; Medicine Quality Research Group, NDM Centre for Global Health Research, Nuffield Department of Medicine, University of Oxford, Oxford, OX3 7LG, UK.; Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, 10400, Thailand.; Infectious Diseases Data Observatory, Nuffield Department of Medicine, University of Oxford, Oxford, OX3 7LG, UK., Zitzmann N; Department of Biochemistry, University of Oxford, Oxford, OX1 3QU, UK.; Kavli Institute for Nanoscience Discovery, University of Oxford, Oxford, OX1 3QU, UK., McCullagh JSO; Department of Chemistry, University of Oxford, Oxford, OX1 3TA, UK. james.mccullagh@chem.ox.ac.uk.
Publikováno v: NPJ vaccines [NPJ Vaccines] 2024 Aug 28; Vol. 9 (1), pp. 155. Date of Electronic Publication: 2024 Aug 28.
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3
Akademický článek
Repurposing rapid diagnostic tests to detect falsified vaccines in supply chains.
Autor: Bharucha T; Department of Biochemistry, University of Oxford, Oxford OX1 3QU, UK; Kavli Institute for Nanoscience Discovery, University of Oxford, Oxford OX1 3QU, UK; Lao-Oxford-Mahosot Hospital-Wellcome Trust Research Unit (LOMWRU), Microbiology Laboratory, Mahosot Hospital, Vientiane, Lao Democratic People's Republic. Electronic address: t.bharucha@doctors.org.uk., Gangadharan B; Department of Biochemistry, University of Oxford, Oxford OX1 3QU, UK; Kavli Institute for Nanoscience Discovery, University of Oxford, Oxford OX1 3QU, UK., Clarke R; Department of Chemistry, University of Oxford, Oxford OX1 3TA, UK., Fernandez LG; Department of Biochemistry, University of Oxford, Oxford OX1 3QU, UK; Kavli Institute for Nanoscience Discovery, University of Oxford, Oxford OX1 3QU, UK., Arman BY; Department of Biochemistry, University of Oxford, Oxford OX1 3QU, UK; Kavli Institute for Nanoscience Discovery, University of Oxford, Oxford OX1 3QU, UK., Walsby-Tickle J; Department of Chemistry, University of Oxford, Oxford OX1 3TA, UK., Deats M; Centre for Tropical Medicine & Global Health, Nuffield Department of Medicine, University of Oxford, Oxford OX3 7LG, UK., Mosca S; Central Laser Facility, Research Complex at Harwell, STFC Rutherford-Appleton Laboratory, UKRI, Harwell Campus, Didcot OX11 0QX, UK., Lin Q; Central Laser Facility, Research Complex at Harwell, STFC Rutherford-Appleton Laboratory, UKRI, Harwell Campus, Didcot OX11 0QX, UK., Stokes R; Agilent Technologies LDA UK, Becquerel Avenue, Didcot OX11 0RA, UK., Dunachie S; Centre for Tropical Medicine & Global Health, Nuffield Department of Medicine, University of Oxford, Oxford OX3 7LG, UK; Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok 10400, Thailand; Department of Microbiology and Infectious Diseases, Oxford University Hospitals NHS Foundation Trust, Oxford OX3 9DU, UK., Merchant HA; Department of Bioscience, School of Health, Sport and Bioscience, University of East London, Water Lane London E15 4LZ, UK; Department of Pharmacy, School of Applied Sciences, University of Huddersfield, Queensgate, Huddersfield HD1 3DH, UK., Dubot-Pérès A; Lao-Oxford-Mahosot Hospital-Wellcome Trust Research Unit (LOMWRU), Microbiology Laboratory, Mahosot Hospital, Vientiane, Lao Democratic People's Republic; Centre for Tropical Medicine & Global Health, Nuffield Department of Medicine, University of Oxford, Oxford OX3 7LG, UK; Unité Des Virus Emergents (UVE: Aix Marseille Univ, IRD190, INSERM 1207), Marseille, France., Caillet C; Lao-Oxford-Mahosot Hospital-Wellcome Trust Research Unit (LOMWRU), Microbiology Laboratory, Mahosot Hospital, Vientiane, Lao Democratic People's Republic; Centre for Tropical Medicine & Global Health, Nuffield Department of Medicine, University of Oxford, Oxford OX3 7LG, UK; Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok 10400, Thailand; Infectious Diseases Data Observatory, Nuffield Department of Medicine, University of Oxford, Oxford OX3 7LG, UK., McCullagh J; Department of Chemistry, University of Oxford, Oxford OX1 3TA, UK., Matousek P; Centre for Tropical Medicine & Global Health, Nuffield Department of Medicine, University of Oxford, Oxford OX3 7LG, UK; Central Laser Facility, Research Complex at Harwell, STFC Rutherford-Appleton Laboratory, UKRI, Harwell Campus, Didcot OX11 0QX, UK., Zitzmann N; Department of Biochemistry, University of Oxford, Oxford OX1 3QU, UK; Kavli Institute for Nanoscience Discovery, University of Oxford, Oxford OX1 3QU, UK., Newton PN; Lao-Oxford-Mahosot Hospital-Wellcome Trust Research Unit (LOMWRU), Microbiology Laboratory, Mahosot Hospital, Vientiane, Lao Democratic People's Republic; Centre for Tropical Medicine & Global Health, Nuffield Department of Medicine, University of Oxford, Oxford OX3 7LG, UK; Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok 10400, Thailand; Infectious Diseases Data Observatory, Nuffield Department of Medicine, University of Oxford, Oxford OX3 7LG, UK. Electronic address: Paul.Newton@tropmedres.ac.
Publikováno v: Vaccine [Vaccine] 2024 Mar 07; Vol. 42 (7), pp. 1506-1511. Date of Electronic Publication: 2024 Feb 14.
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4
Akademický článek
Aldehyde-mediated inhibition of asparagine biosynthesis has implications for diabetes and alcoholism.
Autor: John T; Chemistry Research Laboratory, Department of Chemistry and the Ineos Oxford Institute for Antimicrobial Research, University of Oxford 12 Mansfield Road Oxford OX1 3TA UK christopher.schofield@chem.ox.ac.uk., Saffoon N; Chemistry Research Laboratory, Department of Chemistry and the Ineos Oxford Institute for Antimicrobial Research, University of Oxford 12 Mansfield Road Oxford OX1 3TA UK christopher.schofield@chem.ox.ac.uk., Walsby-Tickle J; Chemistry Research Laboratory, Department of Chemistry and the Ineos Oxford Institute for Antimicrobial Research, University of Oxford 12 Mansfield Road Oxford OX1 3TA UK christopher.schofield@chem.ox.ac.uk., Hester SS; Nuffield Department of Medicine, Target Discovery Institute, University of Oxford Oxford UK., Dingler FA; MRC Weatherall Institute of Molecular Medicine, John Radcliffe Hospital/Headley Way Oxford OX3 9DS UK., Millington CL; MRC Weatherall Institute of Molecular Medicine, John Radcliffe Hospital/Headley Way Oxford OX3 9DS UK., McCullagh JSO; Chemistry Research Laboratory, Department of Chemistry and the Ineos Oxford Institute for Antimicrobial Research, University of Oxford 12 Mansfield Road Oxford OX1 3TA UK christopher.schofield@chem.ox.ac.uk., Patel KJ; MRC Weatherall Institute of Molecular Medicine, John Radcliffe Hospital/Headley Way Oxford OX3 9DS UK., Hopkinson RJ; Leicester Institute for Structural and Chemical Biology and School of Chemistry, University of Leicester, Henry Wellcome Building Lancaster Road Leicester LE1 7RH UK richard.hopkinson@leicester.ac.uk., Schofield CJ; Chemistry Research Laboratory, Department of Chemistry and the Ineos Oxford Institute for Antimicrobial Research, University of Oxford 12 Mansfield Road Oxford OX1 3TA UK christopher.schofield@chem.ox.ac.uk.
Publikováno v: Chemical science [Chem Sci] 2024 Jan 15; Vol. 15 (7), pp. 2509-2517. Date of Electronic Publication: 2024 Jan 15 (Print Publication: 2024).
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6
Akademický článek
Innovative method for rapid detection of falsified COVID-19 vaccines through unopened vials using handheld Spatially Offset Raman Spectroscopy (SORS).
Autor: Mosca S; Central Laser Facility, Research Complex at Harwell, STFC Rutherford Appleton Laboratory, UKRI, Harwell Campus, OX11 0QX, UK., Lin Q; Central Laser Facility, Research Complex at Harwell, STFC Rutherford Appleton Laboratory, UKRI, Harwell Campus, OX11 0QX, UK., Stokes R; Agilent Technologies LDA UK, Becquerel Avenue, Didcot OX11 0RA, UK., Bharucha T; Department of Biochemistry, University of Oxford, Oxford OX1 3QU, UK; Kavli Institute for Nanoscience Discovery, University of Oxford, Oxford OX1 3QU, UK., Gangadharan B; Department of Biochemistry, University of Oxford, Oxford OX1 3QU, UK; Kavli Institute for Nanoscience Discovery, University of Oxford, Oxford OX1 3QU, UK., Clarke R; Department of Chemistry, University of Oxford, Oxford OX1 3TA, UK., Fernandez LG; Department of Biochemistry, University of Oxford, Oxford OX1 3QU, UK; Kavli Institute for Nanoscience Discovery, University of Oxford, Oxford OX1 3QU, UK., Deats M; Medicine Quality Research Group, NDM Centre for Global Health Research, Nuffield Department of Medicine, University of Oxford, Oxford OX3 7LG, UK; Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok 10400, Thailand; Infectious Diseases Data Observatory, Centre of Tropical Medicine & Global Health, Nuffield Department of Medicine, University of Oxford, Oxford OX3 7LG, UK., Walsby-Tickle J; Department of Chemistry, University of Oxford, Oxford OX1 3TA, UK., Arman BY; Department of Biochemistry, University of Oxford, Oxford OX1 3QU, UK; Kavli Institute for Nanoscience Discovery, University of Oxford, Oxford OX1 3QU, UK., Chunekar SR; Serum Institute of India Pvt. Ltd., 212/2, Hadapsar, Pune 411028, India., Patil KD; Serum Institute of India Pvt. Ltd., 212/2, Hadapsar, Pune 411028, India., Gairola S; Serum Institute of India Pvt. Ltd., 212/2, Hadapsar, Pune 411028, India., Van Assche K; Medicine Quality Research Group, NDM Centre for Global Health Research, Nuffield Department of Medicine, University of Oxford, Oxford OX3 7LG, UK; Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok 10400, Thailand; Infectious Diseases Data Observatory, Centre of Tropical Medicine & Global Health, Nuffield Department of Medicine, University of Oxford, Oxford OX3 7LG, UK., Dunachie S; Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok 10400, Thailand; Department of Microbiology and Infectious Diseases, Oxford University Hospitals NHS Foundation Trust, Oxford OX3 9DU, UK; NIHR Oxford Biomedical Research Centre, Oxford University Hospitals NHS Foundation Trust, Oxford OX3 9DU, UK., Merchant HA; Department of Pharmacy, School of Applied Sciences, University of Huddersfield, Queensgate, Huddersfield HD1 3DH, UK., Kuwana R; Regulation and Safety Unit, Regulation and Prequalification Department, Access to Medicines and Health Products Division, World Health Organization (WHO), Geneva, Switzerland., Maes A; Regulation and Safety Unit, Regulation and Prequalification Department, Access to Medicines and Health Products Division, World Health Organization (WHO), Geneva, Switzerland., McCullagh J; Department of Chemistry, University of Oxford, Oxford OX1 3TA, UK., Caillet C; Medicine Quality Research Group, NDM Centre for Global Health Research, Nuffield Department of Medicine, University of Oxford, Oxford OX3 7LG, UK; Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok 10400, Thailand; Infectious Diseases Data Observatory, Centre of Tropical Medicine & Global Health, Nuffield Department of Medicine, University of Oxford, Oxford OX3 7LG, UK., Zitzmann N; Department of Biochemistry, University of Oxford, Oxford OX1 3QU, UK; Kavli Institute for Nanoscience Discovery, University of Oxford, Oxford OX1 3QU, UK., Newton PN; Medicine Quality Research Group, NDM Centre for Global Health Research, Nuffield Department of Medicine, University of Oxford, Oxford OX3 7LG, UK; Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok 10400, Thailand; Infectious Diseases Data Observatory, Centre of Tropical Medicine & Global Health, Nuffield Department of Medicine, University of Oxford, Oxford OX3 7LG, UK. Electronic address: Paul.Newton@tropmedres.ac., Matousek P; Central Laser Facility, Research Complex at Harwell, STFC Rutherford Appleton Laboratory, UKRI, Harwell Campus, OX11 0QX, UK; Medicine Quality Research Group, NDM Centre for Global Health Research, Nuffield Department of Medicine, University of Oxford, Oxford OX3 7LG, UK; Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok 10400, Thailand; Infectious Diseases Data Observatory, Centre of Tropical Medicine & Global Health, Nuffield Department of Medicine, University of Oxford, Oxford OX3 7LG, UK. Electronic address: pavel.matousek@stfc.ac.uk.
Publikováno v: Vaccine [Vaccine] 2023 Nov 13; Vol. 41 (47), pp. 6960-6968. Date of Electronic Publication: 2023 Oct 20.
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7
Investigating isocitrate dehydrogenase mutations in cancer using new metabolomics methods
Autor: Walsby-Tickle, J
Altered cellular metabolism, as a result of oncogenic mutations, has been observed in a range of cancer types. A detailed understanding of how cancers modify cellular metabolism, which includes changes to the genome, proteome and metabolome, is there
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______1064::358855d21efa75cad8fbe9f77acead47
https://ora.ox.ac.uk/objects/uuid:eb55ebc8-ad5d-403a-af9a-b1f21ee21cc8
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8
Akademický článek
Roles of metal ions in the selective inhibition of oncogenic variants of isocitrate dehydrogenase 1.
Autor: Liu S; Chemistry Research Laboratory, Department of Chemistry and the Ineos Oxford Institute for Antimicrobial Research, University of Oxford, 12 Mansfield Road, Oxford, OX1 3TA, UK.; Broad Institute of MIT and Harvard, 415 Main Street, Cambridge, MA, 02142, USA., Abboud MI; Chemistry Research Laboratory, Department of Chemistry and the Ineos Oxford Institute for Antimicrobial Research, University of Oxford, 12 Mansfield Road, Oxford, OX1 3TA, UK.; Department of Natural Sciences, Lebanese American University, Byblos/Beirut, Lebanon., John T; Chemistry Research Laboratory, Department of Chemistry and the Ineos Oxford Institute for Antimicrobial Research, University of Oxford, 12 Mansfield Road, Oxford, OX1 3TA, UK., Mikhailov V; Chemistry Research Laboratory, Department of Chemistry and the Ineos Oxford Institute for Antimicrobial Research, University of Oxford, 12 Mansfield Road, Oxford, OX1 3TA, UK., Hvinden I; Chemistry Research Laboratory, Department of Chemistry and the Ineos Oxford Institute for Antimicrobial Research, University of Oxford, 12 Mansfield Road, Oxford, OX1 3TA, UK., Walsby-Tickle J; Chemistry Research Laboratory, Department of Chemistry and the Ineos Oxford Institute for Antimicrobial Research, University of Oxford, 12 Mansfield Road, Oxford, OX1 3TA, UK., Liu X; Chemistry Research Laboratory, Department of Chemistry and the Ineos Oxford Institute for Antimicrobial Research, University of Oxford, 12 Mansfield Road, Oxford, OX1 3TA, UK., Pettinati I; Chemistry Research Laboratory, Department of Chemistry and the Ineos Oxford Institute for Antimicrobial Research, University of Oxford, 12 Mansfield Road, Oxford, OX1 3TA, UK., Cadoux-Hudson T; Chemistry Research Laboratory, Department of Chemistry and the Ineos Oxford Institute for Antimicrobial Research, University of Oxford, 12 Mansfield Road, Oxford, OX1 3TA, UK., McCullagh JSO; Chemistry Research Laboratory, Department of Chemistry and the Ineos Oxford Institute for Antimicrobial Research, University of Oxford, 12 Mansfield Road, Oxford, OX1 3TA, UK., Schofield CJ; Chemistry Research Laboratory, Department of Chemistry and the Ineos Oxford Institute for Antimicrobial Research, University of Oxford, 12 Mansfield Road, Oxford, OX1 3TA, UK. christopher.schofield@chem.ox.ac.uk.
Publikováno v: Communications biology [Commun Biol] 2021 Nov 01; Vol. 4 (1), pp. 1243. Date of Electronic Publication: 2021 Nov 01.
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9
Akademický článek
Variants in ALDH1A2 reveal an anti-inflammatory role for retinoic acid and a new class of disease-modifying drugs in osteoarthritis.
Autor: Zhu L; Centre for Osteoarthritis Pathogenesis Versus Arthritis, Kennedy Institute of Rheumatology, NDORMS, University of Oxford, Oxford OX3 7FY, UK., Kamalathevan P; Centre for Osteoarthritis Pathogenesis Versus Arthritis, Kennedy Institute of Rheumatology, NDORMS, University of Oxford, Oxford OX3 7FY, UK., Koneva LA; Kennedy Institute of Rheumatology, NDORMS, University of Oxford, Oxford OX3 7FY, UK., Zarebska JM; Centre for Osteoarthritis Pathogenesis Versus Arthritis, Kennedy Institute of Rheumatology, NDORMS, University of Oxford, Oxford OX3 7FY, UK., Chanalaris A; Centre for Osteoarthritis Pathogenesis Versus Arthritis, Kennedy Institute of Rheumatology, NDORMS, University of Oxford, Oxford OX3 7FY, UK., Ismail H; Centre for Osteoarthritis Pathogenesis Versus Arthritis, Kennedy Institute of Rheumatology, NDORMS, University of Oxford, Oxford OX3 7FY, UK.; Healthy Lifespan Institute (HELSI) and Department of Infection, Immunity and Cardiovascular Disease, University of Sheffield, Sheffield S10 2TN, UK., Wiberg A; Botnar Research Centre, Nuffield Department of Orthopaedics Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford OX3 7LD, UK., Ng M; Botnar Research Centre, Nuffield Department of Orthopaedics Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford OX3 7LD, UK., Muhammad H; Centre for Osteoarthritis Pathogenesis Versus Arthritis, Kennedy Institute of Rheumatology, NDORMS, University of Oxford, Oxford OX3 7FY, UK., Walsby-Tickle J; Department of Chemistry, University of Oxford, Mansfield Road, Oxford OX1 3TA, UK., McCullagh JSO; Department of Chemistry, University of Oxford, Mansfield Road, Oxford OX1 3TA, UK., Watt FE; Centre for Osteoarthritis Pathogenesis Versus Arthritis, Kennedy Institute of Rheumatology, NDORMS, University of Oxford, Oxford OX3 7FY, UK.; Centre for Inflammatory Disease, Department of Immunology and Inflammation, Imperial College London, London W12 0NN, UK., Sansom SN; Kennedy Institute of Rheumatology, NDORMS, University of Oxford, Oxford OX3 7FY, UK., Furniss D; Botnar Research Centre, Nuffield Department of Orthopaedics Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford OX3 7LD, UK., Gardiner MD; Centre for Osteoarthritis Pathogenesis Versus Arthritis, Kennedy Institute of Rheumatology, NDORMS, University of Oxford, Oxford OX3 7FY, UK., Vincent TL; Centre for Osteoarthritis Pathogenesis Versus Arthritis, Kennedy Institute of Rheumatology, NDORMS, University of Oxford, Oxford OX3 7FY, UK., Riley N, Spiteri M, McNab I, Little C, Cogswell L, Critchley P, Giele H, Shirley R
Publikováno v: Science translational medicine [Sci Transl Med] 2022 Dec 21; Vol. 14 (676), pp. eabm4054. Date of Electronic Publication: 2022 Dec 21.
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10
Akademický článek
Altered glycolysis triggers impaired mitochondrial metabolism and mTORC1 activation in diabetic β-cells.
Autor: Haythorne E; Department of Physiology, Anatomy and Genetics and OXION, University of Oxford, Parks Road, Oxford, OX1 3PT, UK. Elizabeth.Haythorne@dpag.ox.ac.uk., Lloyd M; Department of Physiology, Anatomy and Genetics and OXION, University of Oxford, Parks Road, Oxford, OX1 3PT, UK., Walsby-Tickle J; Chemistry Research Laboratory, Department of Chemistry, University of Oxford, Mansfield Road, Oxford, OX1 3TA, UK., Tarasov AI; School of Biomedical Sciences, Ulster University, Coleraine, BT52 1SA, Northern Ireland, UK., Sandbrink J; Department of Physiology, Anatomy and Genetics and OXION, University of Oxford, Parks Road, Oxford, OX1 3PT, UK., Portillo I; Department of Physiology, Anatomy and Genetics and OXION, University of Oxford, Parks Road, Oxford, OX1 3PT, UK., Exposito RT; Department of Physiology, Anatomy and Genetics and OXION, University of Oxford, Parks Road, Oxford, OX1 3PT, UK.; Institute for Diabetes and Cancer (IDC), Helmholtz Center, Munich, Neuherberg, 85764, Germany., Sachse G; Department of Physiology, Anatomy and Genetics and OXION, University of Oxford, Parks Road, Oxford, OX1 3PT, UK.; Brandenburg Medical School (Theodor Fontane), ZTM-BB, Brandenburg a. d. H, 14770, Germany., Cyranka M; Department of Physiology, Anatomy and Genetics and OXION, University of Oxford, Parks Road, Oxford, OX1 3PT, UK., Rohm M; Department of Physiology, Anatomy and Genetics and OXION, University of Oxford, Parks Road, Oxford, OX1 3PT, UK.; Institute for Diabetes and Cancer (IDC), Helmholtz Center, Munich, Neuherberg, 85764, Germany., Rorsman P; Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Churchill Hospital, Oxford, OX3 7LJ, UK., McCullagh J; Chemistry Research Laboratory, Department of Chemistry, University of Oxford, Mansfield Road, Oxford, OX1 3TA, UK., Ashcroft FM; Department of Physiology, Anatomy and Genetics and OXION, University of Oxford, Parks Road, Oxford, OX1 3PT, UK. frances.ashcroft@dpag.ox.ac.uk.
Publikováno v: Nature communications [Nat Commun] 2022 Nov 14; Vol. 13 (1), pp. 6754. Date of Electronic Publication: 2022 Nov 14.
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