Linked-read whole-genome sequencing resolves common and private structural variants in multiple myeloma

Autor: Peña-Pérez, Lucía, Frengen, Nicolai, Hauenstein, Julia, Gran, Charlotte, Gustafsson, Charlotte, Eisfeldt, Jesper, Kierczak, Marcin, Taborsak-Lines, Fanny, Olsen, Remi-André, Wallblom, Ann, Krstic, Aleksandra, Ewels, Philip, Lindstrand, Anna, Månsson, Robert ^*

Publikováno v: In Blood Advances 13 September 2022 6(17):5009-5023

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Bioinformatic Analysis of the Wound Peptidome Reveals Potential Biomarkers and Antimicrobial Peptides

Autor: Erik Hartman, Karl Wallblom, Mariena J. A. van der Plas, Jitka Petrlova, Jun Cai, Karim Saleh, Sven Kjellström, Artur Schmidtchen

Publikováno v: Frontiers in Immunology, Vol 11 (2021)

Wound infection is a common and serious medical condition with an unmet need for improved diagnostic tools. A peptidomic approach, aided by mass spectrometry and bioinformatics, could provide novel means of identifying new peptide biomarkers for woun

Externí odkaz: https://doaj.org/article/011829404bbb4db69cd3c391ed863d60

Study protocol for a phase 1, randomised, double-blind, placebo-controlled study to investigate the safety, tolerability and pharmacokinetics of ascending topical doses of TCP-25 applied to epidermal suction blister wounds in healthy male and female volunteers

Autor: Sigrid Lundgren, Karl Wallblom, Jane Fisher, Susanne Erdmann, Artur Schmidtchen, Karim Saleh

Publikováno v: Lundgren, S, Wallblom, K, Fisher, J, Erdmann, S, Schmidtchen, A & Saleh, K 2023, ' Study protocol for a phase 1, randomised, double-blind, placebo-controlled study to investigate the safety, tolerability and pharmacokinetics of ascending topical doses of TCP-25 applied to epidermal suction blister wounds in healthy male and female volunteers ', BMJ Open, vol. 13, no. 2, e064866 . https://doi.org/10.1136/bmjopen-2022-064866

IntroductionTCP-25 gel is intended for use in treatment of wound infection and inflammation. Current local therapies for wounds have limited efficacy to prevent infections and there are no wound treatments available today that target the excessive in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8852811c526c79af4adccf7e5ee43976
https://curis.ku.dk/ws/files/337985137/Study_protocol_for_a_phase_1.pdf

Deletion of Chromosomal Region 8p21 Confers Resistance to Bortezomib and Is Associated with Upregulated Decoy TRAIL Receptor Expression in Patients with Multiple Myeloma.

Autor: Adil Doganay Duru, Tolga Sutlu, Ann Wallblom, Katarina Uttervall, Johan Lund, Birgitta Stellan, Gösta Gahrton, Hareth Nahi, Evren Alici

Publikováno v: PLoS ONE, Vol 10, Iss 9, p e0138248 (2015)

Loss of the chromosomal region 8p21 negatively effects survival in patients with multiple myeloma (MM) that undergo autologous stem cell transplantation (ASCT). In this study, we aimed to identify the immunological and molecular consequences of del(8

Externí odkaz: https://doaj.org/article/c7e22ca094c5472ead947d92c560d36f