Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Wallace S, Chick"'
Autor:
Alicia M. Purkey, Kevin M. Woolfrey, Kevin C. Crosby, Dominik G. Stich, Wallace S. Chick, Jason Aoto, Mark L. Dell’Acqua
Publikováno v:
Cell Reports, Vol 25, Iss 4, Pp 974-987.e4 (2018)
Summary: Ca2+-permeable AMPA-type glutamate receptors (CP-AMPARs) containing GluA1 but lacking GluA2 subunits contribute to multiple forms of synaptic plasticity, including long-term potentiation (LTP), but mechanisms regulating CP-AMPARs are poorly
Externí odkaz:
https://doaj.org/article/5cfe45e1aa0144229d4b3260ef3ae995
Autor:
Vitor F. Martins, Shahriar Tahvilian, Ji H. Kang, Kristoffer Svensson, Byron Hetrick, Wallace S. Chick, Simon Schenk, Carrie E. McCurdy
Publikováno v:
Frontiers in Physiology, Vol 9 (2018)
Introduction: The Phosphoinositide 3-kinase (PI3K) signaling pathway plays an important role in skeletal muscle insulin-stimulated glucose uptake. While whole-body and tissue specific knockout (KO) of individual or combinations of the regulatory subu
Externí odkaz:
https://doaj.org/article/351c4fc78ac246cf92cc52962d9faab1
Autor:
Wallace S Chick, Michael eLudwig, Xiaoyun eZhao, David eKitzenberg, Kristina eWilliams, Thomas E Johnson
Publikováno v:
Frontiers in Genetics, Vol 5 (2014)
Longevity is correlated with stress resistance in many animal models. However, previous efforts through the boosting of the antioxidant defense system did not extend life span, suggesting that longevity related stress resistance is mediated by other
Externí odkaz:
https://doaj.org/article/2426aaacf13741c89e0d0bdc80fa355c
Autor:
Kayo Okamura, Yuji Shiozaki, Shinobu Miyazaki-Anzai, Audrey L. Keenan, Wallace S. Chick, Shohei Kohno, Kristina L. Williams, Makoto Miyazaki, Xiaoyun Zhao
Publikováno v:
The Journal of Biological Chemistry
Vascular calcification (or mineralization) is a common complication of chronic kidney disease (CKD) and is closely associated with increased mortality and morbidity rates. We recently reported that activation of the activating transcription factor 4
Publikováno v:
Cryobiology. 97:255
We report here a new, unbiased forward genetic method that uses transposon-mediated mutagenesis to enable the identification of mutations that confer cryoprotectant toxicity resistance (CTR). Our method is to select for resistance to the toxic effect
Publikováno v:
The FASEB Journal. 32
Autor:
Christopher M. Adams, Audrey L. Keenan, Kayo Okamura, Masashi Masuda, Shinobu Miyazaki-Anzai, Shaikh M. Rahman, Yin Tintut, Kristina L. Williams, Wallace S. Chick, Xiaoyun Zhao, Yuji Shiozaki, Makoto Miyazaki
Emerging evidence indicates that upregulation of the ER stress–induced pro-osteogenic transcription factor ATF4 plays an important role in vascular calcification, a common complication in patients with aging, diabetes, and chronic kidney disease (C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f36e32da2ac3cc4e446d1984942a309
https://europepmc.org/articles/PMC5085604/
https://europepmc.org/articles/PMC5085604/
Autor:
Wallace S. Chick, Elaine B. Spector, Mihret T. Elos, Eric P. Wartchow, Mark A. Lovell, Johan L.K. Van Hove, Kathryn C. Chatfield, Jan Riemer, Alican J. Erdogan, Katherine Gowan, Curtis R. Coughlin, Hua Jiang, Courtney P. O’Rourke, Marisa W. Friederich
Publikováno v:
Human molecular genetics. 26(4)
An infant presented with fatal infantile lactic acidosis and cardiomyopathy, and was found to have profoundly decreased activity of respiratory chain complex I in muscle, heart and liver. Exome sequencing revealed compound heterozygous mutations in N
Autor:
Courtney E. Wilson, Jeremy D. Bushman, Wallace S. Chick, Alexander J. Cooper, Eric M. Mulhall, Sue C. Kinnamon, Yu-Hsiang Tu, Rui B. Chang, Mark T. Nelson, Emily R. Liman, David C. Hill-Eubanks, Wenlei Ye
Publikováno v:
Biophysical Journal. 110(3)
Sour taste is detected by a subset of taste cells on the tongue and palate epithelium that respond to acids with trains of action potentials. Entry of protons through a Zn2+-sensitive proton conductance that is specific to sour taste cells has been s
Autor:
Emily S. Gibson, Jennifer L. Sanderson, Jessica A. Gorski, Ronald K. Freund, Mark L. Dell'Acqua, Philip Lam, Wallace S. Chick
Publikováno v:
The Journal of Neuroscience. 32:15036-15052
AMPA receptors (AMPARs) are tetrameric ion channels assembled from GluA1–GluA4 subunits that mediate the majority of fast excitatory synaptic transmission in the brain. In the hippocampus, most synaptic AMPARs are composed of GluA1/2 or GluA2/3 wit