Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Wallace Liu"'
Autor:
Stefan Vasile, Torkel Vang, Laurence Delacroix, Rebecca Page, Robert C. Rickert, Benedicte A. Lie, Souad Rahmouni, Tomas Mustelin, Johannes Landskron, Wallace Liu, Kjetil Taskén, Li-Li Yang, Michel L. Tremblay, Lucia Musumeci, Shuangding Wu, Dana M. Francis, Russell Dahl, Lutz Tautz
Publikováno v:
Nature chemical biology
Lymphoid tyrosine phosphatase (LYP) and C-terminal Src kinase (CSK) are negative regulators of signaling mediated through the T cell antigen receptor (TCR) and are thought to act in a cooperative manner when forming a complex. Here, we studied the sp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd54191484e5ba587051b236d5d98907
https://doi.org/10.1038/nchembio.916
https://doi.org/10.1038/nchembio.916
Autor:
Xochella Chan, Eduard Sergienko, David A Critton, Ekaterina V. Bobkova, Nicholas D. P. Cosford, Li Yang, Rebecca Page, Paul J. Lombroso, Brock Brown, Shyama Sidique, Justin Rascon, Stefan Vasile, Ying Su, Thomas D.Y. Chung, Russell Dahl, Tomas Mustelin, Hongbin Yuan, Sharon Colayco, Wallace Liu, Lutz Tautz, Jian Xu
Publikováno v:
ACS Chemical Biology. 7:367-377
The hematopoietic protein tyrosine phosphatase (HePTP) is implicated in the development of blood cancers through its ability to negatively regulate the mitogen-activated protein kinases (MAPKs) ERK1/2 and p38. Small-molecule modulators of HePTP activ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01a0a8233e260ab3586098511742b7ce
https://doi.org/10.1021/cb2004274
https://doi.org/10.1021/cb2004274
Autor:
Ekaterina V. Bobkova, Wallace Liu, Lutz Tautz, Xochella Chan, David A Critton, Stefan Vasile, Rebecca Page, Tomas Mustelin, Sharon Colayco, Thomas D.Y. Chung, Carlton Gasior, Ying Su, Justin Rascon, Russell Dahl, Eduard Sergienko
Publikováno v:
ACS Medicinal Chemistry Letters. 2:113-118
Protein tyrosine phosphatases (PTPs) have only recently become the focus of attention in the search for novel drug targets despite the fact that they play vital roles in numerous cellular processes and are implicated in many human diseases. The hemat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9bd638a68deb48d70a6fa99790e71f0d
https://doi.org/10.1021/ml100103p
https://doi.org/10.1021/ml100103p
Publikováno v:
Methods in Molecular Biology ISBN: 9781627035613
Methods Mol Biol
Methods Mol Biol
The importance of tyrosine phosphorylation in normal cell physiology is well established, highlighted by the many human diseases that stem from abnormalities in protein tyrosine kinase (PTK) and protein tyrosine phosphatase (PTP) function. Contrary t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b945177c699c2606d565f1204c8fb3b9
https://doi.org/10.1007/978-1-62703-562-0_15
https://doi.org/10.1007/978-1-62703-562-0_15
Autor:
Deborah H. Smith, Alison Rinderspacher, Shi Xian Deng, Dusica Vidovic, Torkel Vang, Stephan C. Schürer, Tomas Mustelin, Robert C. Rickert, Yidong Liu, Donald W. Landry, Yuli Xie, Gangli Gong, Wallace Liu, Lutz Tautz, Caty Chung, Shuangding Wu
Publikováno v:
Journal of medicinal chemistry. 54(2)
The lymphoid tyrosine phosphatase (Lyp, PTPN22) is a critical negative regulator of T cell antigen receptor (TCR) signaling. A single-nucleotide polymorphism (SNP) in the ptpn22 gene correlates with the incidence of various autoimmune diseases, inclu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d1e6dcee9a12cd81f96edf75c5f1ea2
https://pubmed.ncbi.nlm.nih.gov/21190368
https://pubmed.ncbi.nlm.nih.gov/21190368
Publikováno v:
The Journal of Data Education. 24:23-24
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d73e40344073f7cc9a018025f2d7bef3
https://doi.org/10.1080/00220310.1983.11646282
https://doi.org/10.1080/00220310.1983.11646282