Zobrazeno 1 - 10
of 181
pro vyhledávání: '"Wallace K, MacNaughton"'
Autor:
Sruthi Rajeev, ShuHua Li, Aralia Leon-Coria, Arthur Wang, Lucas Kraemer, Susan Joanne Wang, Annaliese Boim, Kyle Flannigan, Adam Shute, Cristiane H Baggio, Blanca E Callejas, Wallace K MacNaughton, Constance A M Finney, Derek M McKay
Publikováno v:
PLoS Pathogens, Vol 20, Iss 7, p e1012381 (2024)
Recognizing that enteric tuft cells can signal the presence of nematode parasites, we investigated whether tuft cells are required for the expulsion of the cestode, Hymenolepis diminuta, from the non-permissive mouse host, and in concomitant anti-hel
Externí odkaz:
https://doaj.org/article/4b9f7af5d33445d9957cca21ab26e215
Autor:
Erik van Tilburg Bernardes, Veronika Kuchařová Pettersen, Mackenzie W. Gutierrez, Isabelle Laforest-Lapointe, Nicholas G. Jendzjowsky, Jean-Baptiste Cavin, Fernando A. Vicentini, Catherine M. Keenan, Hena R. Ramay, Jumana Samara, Wallace K. MacNaughton, Richard J. A. Wilson, Margaret M. Kelly, Kathy D. McCoy, Keith A. Sharkey, Marie-Claire Arrieta
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
The immunomodulatory role of commensal gut fungi and interactions with bacteria remain unclear. Here, using germ-free mice colonized with defined species of bacteria and fungi, the authors find that fungal colonization induces changes in bacterial mi
Externí odkaz:
https://doaj.org/article/7e7a71db7d15468095e5d2a5ace43434
Autor:
Vinicius M. Gadotti, Graciela Andonegui, Zizhen Zhang, Said M'Dahoma, Cristiane H. Baggio, Lina Chen, Lilian Basso, Christophe Altier, Wallace K. MacNaughton, Paul Kubes, Gerald W. Zamponi
Publikováno v:
iScience, Vol 16, Iss , Pp 12-21 (2019)
Summary: Many patients with visceral inflammation develop pain and psychiatric comorbidities such as major depressive disorder, worsening the quality of life and increasing the risk of suicide. Here we show that neuroimmune activation in mice with de
Externí odkaz:
https://doaj.org/article/dc7ebaf0f7984e69ae4a70378c6bccf8
Autor:
Jean‐Baptiste Cavin, Preedajit Wongkrasant, Joel B. Glover, Onesmo B. Balemba, Wallace K. MacNaughton, Keith A. Sharkey
Publikováno v:
The Journal of Physiology. 601:1183-1206
Autor:
Helvira Melo, Lilian Basso, Mircea Iftinca, Wallace K. MacNaughton, Morley D. Hollenberg, Derek M. McKay, Christophe Altier
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-9 (2018)
Abstract Opioids remain the gold standard for the treatment of moderate to severe pain. However, their analgesic properties come with important side effects, including pruritus, which occurs frequently after systemic or neuraxial administration. Alth
Externí odkaz:
https://doaj.org/article/42ced415c4b94ea690383c643cde70f5
Autor:
Hailey, Cuddihey, Jean-Baptiste, Cavin, Catherine M, Keenan, Laurie E, Wallace, Kiran, Vemuri, Alexandros, Makriyannis, Wallace K, MacNaughton, Keith A, Sharkey
Publikováno v:
American journal of physiology. Gastrointestinal and liver physiology. 323(3)
The endocannabinoid system of the gastrointestinal tract is involved in the control of intestinal barrier function. Whether the cannabinoid 1 (CB
Autor:
Hailey Cuddihey, Jean-Baptiste Cavin, Catherine M. Keenan, Laurie E. Wallace, Kiran Vemuri, Alexandros Makriyannis, Wallace K. MacNaughton, Keith A. Sharkey
Publikováno v:
American Journal of Physiology-Gastrointestinal and Liver Physiology. 323:G219-G238
The endocannabinoid system of the gastrointestinal tract regulates homeostasis by acting as brake on motility and secretion. Here we show that when exposed to a high fat diet, intestinal permeability is increased and activation of the CB1 receptor on
Autor:
Bianca Crifo, Wallace K. MacNaughton
Publikováno v:
American Journal of Physiology-Gastrointestinal and Liver Physiology. 322:G169-G182
Mucosal and histological healing have become the gold standards for assessing the efficacy of therapy in patients living with inflammatory bowel diseases (IBD). Despite these being the accepted goals in therapy, the mechanisms that underlie the heali
Autor:
Kelcie A Lahey, Natalie J Ronaghan, Judie Shang, Sébastien P Dion, Antoine Désilets, Richard Leduc, Wallace K MacNaughton
Publikováno v:
PLoS ONE, Vol 12, Iss 7, p e0180259 (2017)
Changes in barrier function of the gastrointestinal tract are thought to contribute to the inflammatory bowel diseases Crohn's disease and ulcerative colitis. Previous work in our lab demonstrated that apical exposure of intestinal epithelial cell li
Externí odkaz:
https://doaj.org/article/b44bc67df142412d959c2b40a2030a9f
Publikováno v:
American Journal of Physiology-Gastrointestinal and Liver Physiology. 318:G254-G264
The small intestine regulates barrier function to absorb nutrients while avoiding the entry of potentially harmful substances or bacteria. Barrier function is dynamically regulated in part by the enteric nervous system (ENS). The role of the ENS in r