Zobrazeno 1 - 10
of 53
pro vyhledávání: '"Wallace J. Murray"'
Publikováno v:
Acta Pharmacologica Sinica. 31:150-159
To investigate the potential antagonistic activity of the antidiabetic agent glybenclamide for the human platelet thromboxane A(2) receptor (abbreviated as TPR).Platelets were obtained from healthy donors. Aggregation studies were performed in a mode
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::945826e55c948b8e0e7965ba25e8f6f3
https://doi.org/10.1038/aps.2009.195
https://doi.org/10.1038/aps.2009.195
Publikováno v:
Quantitative Structure-Activity Relationships. 12:239-245
A comparison is made between classical QSAR approaches using multivariate linear regression analysis and molecular similarity analysis (MSA) using inhibitors of dihydrofolate reductase (DHFR). A wide variety of descriptors derived directly from molec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::167b4104c5ccd8ea8b627e0322047fcf
https://doi.org/10.1002/qsar.19930120304
https://doi.org/10.1002/qsar.19930120304
Autor:
Paul W. Jungnickel, Wallace J. Murray
Publikováno v:
Journal of Pharmacy Teaching. 2:29-40
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ed1cc00d94103ef7798988baabe7e103
https://doi.org/10.1300/j060v02n01_04
https://doi.org/10.1300/j060v02n01_04
Publikováno v:
Blood. 114:2994-2994
Abstract 2994 Poster Board II-971 While proper platelet function is a vital component of hemostasis, inappropriate activation of platelets contributes to occlusive disorders such as myocardial infarction, and stroke. One pathway for platelet activati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::48b5f1e0c0717bc774bf80bc1bcffd13
https://doi.org/10.1182/blood.v114.22.2994.2994
https://doi.org/10.1182/blood.v114.22.2994.2994
Publikováno v:
Xenobiotica; the fate of foreign compounds in biological systems. 20(9)
1. 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCCD)-induced lipid peroxidation has previously been demonstrated by assessing the hepatic content of thiobarbituric acid reactive substances (TBARS) as well as the NADPH-dependent microsomal formation of TBARS
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af8f1347f511869f0af66f2f86d881ba
https://pubmed.ncbi.nlm.nih.gov/2238714
https://pubmed.ncbi.nlm.nih.gov/2238714
Publikováno v:
Journal of toxicology and environmental health. 31(1)
Microcystin-LR (MCLR), a cyclic heptapeptide produced by the blue-green algae Microcystis aeruginosa, produces death in female mice treated with 100 micrograms MCLR/kg. Kupffer-cell hyperplasia was observed histologically after treatment with 50 or 1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7f3d9b415caf81845c43744b5f660e6
https://pubmed.ncbi.nlm.nih.gov/2120461
https://pubmed.ncbi.nlm.nih.gov/2120461
Publikováno v:
Journal of applied toxicology : JAT. 10(2)
Desferrioxamine (DFX), an iron chelator, has been used to inhibit in vitro redox cycling of the transition iron ions that may interfere with free-radical formation, and is used clinically to treat conditions associated with iron overload. The effect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66f7944e6b8850de1f7334756c1cc591
https://pubmed.ncbi.nlm.nih.gov/2362077
https://pubmed.ncbi.nlm.nih.gov/2362077
Publikováno v:
International Journal of Pharmaceutics. 41:227-230
Nifedipine, like most nitrophenyldihydropyridine derivatives, undergoes rapid photochemical oxidation to the corresponding nitrophenylpyridine when exposed to light. This is accompanied by a remarkable diminution of the pharmacological activity. In t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f40bc24f2f07347cc2ce359936512bb6
https://doi.org/10.1016/0378-5173(88)90197-4
https://doi.org/10.1016/0378-5173(88)90197-4
Publikováno v:
Archives of Environmental Contamination and Toxicology. 16:159-166
The effect of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)2 administration to rats on lipid peroxidation (microsomal malondialdehyde formation and hepatic malondialdehyde content) was determined by the thiobarbituric acid method. The results demonstrat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc73ef5dec17d3705de5c4ead101d327
https://doi.org/10.1007/bf01055797
https://doi.org/10.1007/bf01055797
Publikováno v:
Bulletin of Environmental Contamination and Toxicology. 34:787-796
Administration orale de TCDD a des rats apres un pretraitement oral par BHA ou glutathion et etude du role protecteur du BHA et du glutathion au niveau de la peroxydation lipidique. Action de ces protecteurs sur l'activite de la glutathion peroxydase
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54802c97bd69daa42c8e81fec64a0487
https://doi.org/10.1007/bf01609808
https://doi.org/10.1007/bf01609808