Výsledky vyhledávání - "Wallace, Bonnie A."

The PCDDB (Protein Circular Dichroism Data Bank): a bioinformatics resource for protein characterisations and methods development

Autor: Ramalli, S.G., Miles, Andrew, Janes, R.W., Wallace, Bonnie A.

The Protein Circular Dichroism Data Bank (PCDDB) [https://pcddb.cryst.bbk.ac.uk] is an established resource for the biological, biophysical, chemical, bioinformatics, and molecular biology communities. It is a freely-accessible repository of validate

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=core_ac_uk__::d7c951814894f56886565abb22ee3023
https://eprints.bbk.ac.uk/id/eprint/47259/1/47259.pdf

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Tools and methods for Circular Dichroism Spectroscopy of proteins

Autor: Miles, Andrew, Janes, R.W., Wallace, Bonnie A.

Circular dichroism (CD) spectroscopy is a widely-used method in biochemistry, structural biology and pharmaceutical chemistry. More than 24 000 papers published in the past decade have included CD characterisations of proteins; many of those studies

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=core_ac_uk__::cec15c9f0795acbc8841dd87fdfd559f
https://eprints.bbk.ac.uk/id/eprint/43986/1/43986.pdf

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Cannabidiol interactions with voltage-gated sodium channels

Autor: Sait, L.G., Sula, A., Ghovanloo, M.-R., Hollingworth, D., Ruben, P.C., Wallace, Bonnie A.

Voltage-gated sodium channels are targets for a range of pharmaceutical drugs developed for the treatment of neurological diseases. Cannabidiol (CBD), the non-psychoactive compound isolated from cannabis plants, was recently approved for treatment of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=core_ac_uk__::ab55914136a1c1e64a15b4d5368bb8b2
https://eprints.bbk.ac.uk/id/eprint/41438/1/41438.pdf

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Interactions of amphipathic α-helical MEG proteins from Schistosoma mansoni with membranes

Autor: Felizatti, A.P., Zeraik, A.E., Basso, L.G.M., Kumagai, P.S., Lopes, J.L.S., Wallace, Bonnie A., Araujo, A.P.U., DeMarco, R.

Micro Exon Gene (MEG) proteins are thought to play major roles in the infection and survival of parasitic Schistosoma mansoni worms in host organisms. Here, the physical chemical properties of two small MEG proteins found in the genome of S. mansoni,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=core_ac_uk__::6f0e86ad1d4d6294d68e98f9c004a1d8
https://eprints.bbk.ac.uk/id/eprint/30588/1/30588.pdf

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Akademický článek

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Unveiling the binding and orientation of the antimicrobial peptide Plantaricin 149 in zwitterionic and negatively charged membranes

Autor: Kumagai, P.S., Sousa, V.K., Donato, M., Itri, R., Beltramini, L.M., Araujo, A.P.U., Buerck, J., Wallace, Bonnie A., Lopes, J.L.S.

Antimicrobial peptides are a large group of natural compounds which present promising properties for the pharmaceutical and food industries, such as broad-spectrum activity, potential for use as natural preservatives, and reduced propensity for devel

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=core_ac_uk__::832fa92c152aa47f45d2581a1653b6a6
https://eprints.bbk.ac.uk/id/eprint/28003/1/28003.pdf

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An intrinsically disordered proteins community for ELIXIR

Autor: Davey, Norman E., Felli, Isabella C., Gibson, Toby J., Gutmanas, Aleksandras, Hancock, John M., Harrow, Jen, Higgins, Desmond, Jeffries, Cy M., Le Mercier, Philippe, Mészáros, Balint, Necci, Marco, Babu, M. Madan, Notredame, Cedric, Orchard, Sandra, Ouzounis, Christos A., Pancsa, Rita, Papaleo, Elena, Pierattelli, Roberta, Piovesan, Damiano, Promponas, Vasilis J., Ruch, Patrick, Rustici, Gabriella, Blackledge, Martin, Romero, Pedro, Sarntivijai, Sirarat, Saunders, Gary, Schuler, Benjamin, Sharan, Malvika, Shields, Denis C., Sussman, Joel L., Tedds, Jonathan A., Tompa, Peter, Turewicz, Michael, Bridge, Alan, Vondrasek, Jiri, Vranken, Wim F., Wallace, Bonnie Ann, Wichapong, Kanin, Tosatto, Silvio C. E., Capella-Gutierrez, Salvador, Dosztanyi, Zsuzsanna, Drysdale, Rachel, Edwards, Richard J., Elofsson, Arne

Publikováno v: F1000Research
Apollo
Zurich Open Repository and Archive
PubMed Central
Datacite
UnpayWall
ORCID
Microsoft Academic Graph
UPF Digital Repository
NARCIS
GNOSIS Institutional Repository
CORE (RIOXX-UK Aggregator)
nlmid: 101594320
F1000Research, 8, 1-19. F1000 Research Ltd.
F1000Res
Davey, Norman E; Babu, M Madan; Blackledge, Martin; Bridge, Alan; Capella-Gutierrez, Salvador; Dosztanyi, Zsuzsanna; Drysdale, Rachel; Edwards, Richard J; Elofsson, Arne; Felli, Isabella C; Gibson, Toby J; Gutmanas, Aleksandras; Hancock, John M; Harrow, Jen; Higgins, Desmond; Jeffries, Cy M; Le Mercier, Philippe; Mészáros, Balint; Necci, Marco; Notredame, Cedric; Orchard, Sandra; Ouzounis, Christos A; Pancsa, Rita; Papaleo, Elena; Pierattelli, Roberta; Piovesan, Damiano; Promponas, Vasilis J; Ruch, Patrick; Rustici, Gabriella; Romero, Pedro; et al (2019). An intrinsically disordered proteins community for ELIXIR. F1000Research, 8:1753.
essn: 2046-1402

Intrinsically disordered proteins (IDPs) and intrinsically disordered regions (IDRs) are now recognised as major determinants in cellular regulation. This white paper presents a roadmap for future e-infrastructure developments in the field of IDP res

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0e437b40706cae5031347a484ba4a2c
https://www.repository.cam.ac.uk/handle/1810/300791

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Akademický článek

Tamoxifen complexes with the voltage-gated sodium channel reveal novel drug binding sites

Autor: Hollingworth, David, Wallace, Bonnie A., Sula, Altin

Publikováno v: In Biophysical Journal 11 February 2022 121(3) Supplement 1:24a-24a

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Role of the Interaction Motif in Maintaining the Open Gate of an Open Sodium Channel

Autor: Ke, S., Ulmschneider, M.B., Wallace, Bonnie A., Ulmschneider, J.P.

Voltage-gated sodium channels undergo transitions between open, closed, and inactivated states, enabling regulation of the translocation of sodium ions across membranes. A recently published crystal structure of the full-length prokaryotic NavMs crys

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=core_ac_uk__::2818a2480074a588eac7bb61563b4a83
https://eprints.bbk.ac.uk/id/eprint/24880/1/24880.pdf

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Thermal melt circular dichroism spectroscopic studies for identifying stabilising amphipathic molecules for the voltage-gated sodium channel NavMs

Autor: Ireland, Sam, Sula, Altin, Wallace, Bonnie A.

Purified integral membrane proteins require amphipathic molecules to maintain their solubility in aqueous solutions. These complexes, in turn, are used in studies to characterise the protein structures by a variety of biophysical and structural techn

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=core_ac_uk__::c5e5fbe71409f4a82b77ff63226bd76e
https://eprints.bbk.ac.uk/id/eprint/23548/1/23548.pdf

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