The PCDDB (Protein Circular Dichroism Data Bank): a bioinformatics resource for protein characterisations and methods development

Autor: Ramalli, S.G., Miles, Andrew, Janes, R.W., Wallace, Bonnie A.

The Protein Circular Dichroism Data Bank (PCDDB) [https://pcddb.cryst.bbk.ac.uk] is an established resource for the biological, biophysical, chemical, bioinformatics, and molecular biology communities. It is a freely-accessible repository of validate

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=core_ac_uk__::d7c951814894f56886565abb22ee3023
https://eprints.bbk.ac.uk/id/eprint/47259/1/47259.pdf

Tools and methods for Circular Dichroism Spectroscopy of proteins

Autor: Miles, Andrew, Janes, R.W., Wallace, Bonnie A.

Circular dichroism (CD) spectroscopy is a widely-used method in biochemistry, structural biology and pharmaceutical chemistry. More than 24 000 papers published in the past decade have included CD characterisations of proteins; many of those studies

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=core_ac_uk__::cec15c9f0795acbc8841dd87fdfd559f
https://eprints.bbk.ac.uk/id/eprint/43986/1/43986.pdf

Cannabidiol interactions with voltage-gated sodium channels

Autor: Sait, L.G., Sula, A., Ghovanloo, M.-R., Hollingworth, D., Ruben, P.C., Wallace, Bonnie A.

Voltage-gated sodium channels are targets for a range of pharmaceutical drugs developed for the treatment of neurological diseases. Cannabidiol (CBD), the non-psychoactive compound isolated from cannabis plants, was recently approved for treatment of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=core_ac_uk__::ab55914136a1c1e64a15b4d5368bb8b2
https://eprints.bbk.ac.uk/id/eprint/41438/1/41438.pdf

Interactions of amphipathic α-helical MEG proteins from Schistosoma mansoni with membranes

Autor: Felizatti, A.P., Zeraik, A.E., Basso, L.G.M., Kumagai, P.S., Lopes, J.L.S., Wallace, Bonnie A., Araujo, A.P.U., DeMarco, R.

Micro Exon Gene (MEG) proteins are thought to play major roles in the infection and survival of parasitic Schistosoma mansoni worms in host organisms. Here, the physical chemical properties of two small MEG proteins found in the genome of S. mansoni,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=core_ac_uk__::6f0e86ad1d4d6294d68e98f9c004a1d8
https://eprints.bbk.ac.uk/id/eprint/30588/1/30588.pdf

An intrinsically disordered proteins community for ELIXIR

Autor: Davey, Norman E., Felli, Isabella C., Gibson, Toby J., Gutmanas, Aleksandras, Hancock, John M., Harrow, Jen, Higgins, Desmond, Jeffries, Cy M., Le Mercier, Philippe, Mészáros, Balint, Necci, Marco, Babu, M. Madan, Notredame, Cedric, Orchard, Sandra, Ouzounis, Christos A., Pancsa, Rita, Papaleo, Elena, Pierattelli, Roberta, Piovesan, Damiano, Promponas, Vasilis J., Ruch, Patrick, Rustici, Gabriella, Blackledge, Martin, Romero, Pedro, Sarntivijai, Sirarat, Saunders, Gary, Schuler, Benjamin, Sharan, Malvika, Shields, Denis C., Sussman, Joel L., Tedds, Jonathan A., Tompa, Peter, Turewicz, Michael, Bridge, Alan, Vondrasek, Jiri, Vranken, Wim F., Wallace, Bonnie Ann, Wichapong, Kanin, Tosatto, Silvio C. E., Capella-Gutierrez, Salvador, Dosztanyi, Zsuzsanna, Drysdale, Rachel, Edwards, Richard J., Elofsson, Arne

Publikováno v: F1000Research
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Zurich Open Repository and Archive
PubMed Central
Datacite
UnpayWall
ORCID
Microsoft Academic Graph
UPF Digital Repository
NARCIS
GNOSIS Institutional Repository
CORE (RIOXX-UK Aggregator)
nlmid: 101594320
F1000Research, 8, 1-19. F1000 Research Ltd.
F1000Res
Davey, Norman E; Babu, M Madan; Blackledge, Martin; Bridge, Alan; Capella-Gutierrez, Salvador; Dosztanyi, Zsuzsanna; Drysdale, Rachel; Edwards, Richard J; Elofsson, Arne; Felli, Isabella C; Gibson, Toby J; Gutmanas, Aleksandras; Hancock, John M; Harrow, Jen; Higgins, Desmond; Jeffries, Cy M; Le Mercier, Philippe; Mészáros, Balint; Necci, Marco; Notredame, Cedric; Orchard, Sandra; Ouzounis, Christos A; Pancsa, Rita; Papaleo, Elena; Pierattelli, Roberta; Piovesan, Damiano; Promponas, Vasilis J; Ruch, Patrick; Rustici, Gabriella; Romero, Pedro; et al (2019). An intrinsically disordered proteins community for ELIXIR. F1000Research, 8:1753.
essn: 2046-1402

Intrinsically disordered proteins (IDPs) and intrinsically disordered regions (IDRs) are now recognised as major determinants in cellular regulation. This white paper presents a roadmap for future e-infrastructure developments in the field of IDP res

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0e437b40706cae5031347a484ba4a2c
https://www.repository.cam.ac.uk/handle/1810/300791