Integration across biophysical scales identifies molecular and cellular correlates of person-to-person variability in human brain connectivity.

Autor: Ng B; Rush Alzheimer's Disease Center, Rush University Medical Center, Chicago, IL, USA.; Department of Psychiatry, SUNY Upstate Medical University, Syracuse, NY, USA., Tasaki S; Rush Alzheimer's Disease Center, Rush University Medical Center, Chicago, IL, USA., Greathouse KM; Department of Neurology, Center for Neurodegeneration and Experimental Therapeutics, University of Alabama at Birmingham, Birmingham, AL, USA., Walker CK; Department of Neurology, Center for Neurodegeneration and Experimental Therapeutics, University of Alabama at Birmingham, Birmingham, AL, USA., Zhang A; Department of Psychiatry, SUNY Upstate Medical University, Syracuse, NY, USA., Covitz S; Penn/CHOP Lifespan Brain Institute, University of Pennsylvania, Philadelphia, PA, USA.; Department of Psychiatry, University of Pennsylvania, Philadelphia, PA, USA.; Penn Lifespan Informatics and Neuroimaging Center, University of Pennsylvania, Philadelphia, PA, USA., Cieslak M; Penn/CHOP Lifespan Brain Institute, University of Pennsylvania, Philadelphia, PA, USA.; Department of Psychiatry, University of Pennsylvania, Philadelphia, PA, USA.; Penn Lifespan Informatics and Neuroimaging Center, University of Pennsylvania, Philadelphia, PA, USA., Weber AJ; Department of Neurology, Center for Neurodegeneration and Experimental Therapeutics, University of Alabama at Birmingham, Birmingham, AL, USA., Adamson AB; Department of Neurology, Center for Neurodegeneration and Experimental Therapeutics, University of Alabama at Birmingham, Birmingham, AL, USA., Andrade JP; Department of Neurology, Center for Neurodegeneration and Experimental Therapeutics, University of Alabama at Birmingham, Birmingham, AL, USA., Poovey EH; Department of Neurology, Center for Neurodegeneration and Experimental Therapeutics, University of Alabama at Birmingham, Birmingham, AL, USA., Curtis KA; Department of Neurology, Center for Neurodegeneration and Experimental Therapeutics, University of Alabama at Birmingham, Birmingham, AL, USA., Muhammad HM; Department of Neurology, Center for Neurodegeneration and Experimental Therapeutics, University of Alabama at Birmingham, Birmingham, AL, USA., Seidlitz J; Penn/CHOP Lifespan Brain Institute, University of Pennsylvania, Philadelphia, PA, USA.; Department of Psychiatry, University of Pennsylvania, Philadelphia, PA, USA.; Penn Lifespan Informatics and Neuroimaging Center, University of Pennsylvania, Philadelphia, PA, USA.; Department of Child and Adolescent Psychiatry and Behavioral Science, The Children's Hospital of Philadelphia, Philadelphia, PA, USA., Satterthwaite T; Penn/CHOP Lifespan Brain Institute, University of Pennsylvania, Philadelphia, PA, USA.; Department of Psychiatry, University of Pennsylvania, Philadelphia, PA, USA.; Penn Lifespan Informatics and Neuroimaging Center, University of Pennsylvania, Philadelphia, PA, USA., Bennett DA; Rush Alzheimer's Disease Center, Rush University Medical Center, Chicago, IL, USA., Seyfried NT; Department of Biochemistry, Emory University School of Medicine, Atlanta, GA, USA., Vogel J; Penn/CHOP Lifespan Brain Institute, University of Pennsylvania, Philadelphia, PA, USA.; Department of Psychiatry, University of Pennsylvania, Philadelphia, PA, USA.; Penn Lifespan Informatics and Neuroimaging Center, University of Pennsylvania, Philadelphia, PA, USA.; Department of Clinical Science, Malmö, SciLifeLab, Lund University, Lund, Sweden., Gaiteri C; Rush Alzheimer's Disease Center, Rush University Medical Center, Chicago, IL, USA. gaiteri@gmail.com.; Department of Psychiatry, SUNY Upstate Medical University, Syracuse, NY, USA. gaiteri@gmail.com., Herskowitz JH; Department of Neurology, Center for Neurodegeneration and Experimental Therapeutics, University of Alabama at Birmingham, Birmingham, AL, USA. jhersko@uab.edu.

Publikováno v: Nature neuroscience [Nat Neurosci] 2024 Nov; Vol. 27 (11), pp. 2240-2252. Date of Electronic Publication: 2024 Oct 31.

Modeling late-onset Alzheimer's disease neuropathology via direct neuronal reprogramming.

Autor: Sun Z; Department of Developmental Biology, Washington University School of Medicine, St. Louis, MO 63110, USA.; Center for Regenerative Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA.; Hope Center for Neurological Disorders, Washington University School of Medicine, St. Louis, MO 63110, USA., Kwon JS; Department of Developmental Biology, Washington University School of Medicine, St. Louis, MO 63110, USA.; Program in Computational and Systems Biology, Washington University School of Medicine, St. Louis, MO 63110, USA., Ren Y; Department of Developmental Biology, Washington University School of Medicine, St. Louis, MO 63110, USA.; Program in Developmental, Regenerative, and Stem Cell Biology, Washington University School of Medicine, St. Louis, MO 63110, USA., Chen S; Department of Developmental Biology, Washington University School of Medicine, St. Louis, MO 63110, USA.; Center for Regenerative Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA.; Hope Center for Neurological Disorders, Washington University School of Medicine, St. Louis, MO 63110, USA., Walker CK; Department of Developmental Biology, Washington University School of Medicine, St. Louis, MO 63110, USA.; Center for Regenerative Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA.; Hope Center for Neurological Disorders, Washington University School of Medicine, St. Louis, MO 63110, USA., Lu X; Department of Psychiatry, Washington University School of Medicine, St. Louis, MO 63110, USA., Cates K; Department of Developmental Biology, Washington University School of Medicine, St. Louis, MO 63110, USA.; Program in Molecular Genetics and Genomics, Washington University School of Medicine, St. Louis, MO 63110, USA., Karahan H; Stark Neurosciences Research Institute, Indiana University School of Medicine, Indianapolis, IN 46202, USA.; Department of Medical and Molecular Genetics, Indiana University School of Medicine, Indianapolis, IN 46202, USA., Sviben S; Washington University Center for Cellular Imaging, Washington University School of Medicine, St. Louis, MO 63110, USA., Fitzpatrick JAJ; Washington University Center for Cellular Imaging, Washington University School of Medicine, St. Louis, MO 63110, USA., Valdez C; Center for Alzheimer's and Neurodegenerative Diseases, Peter O'Donnell Jr. Brain Institute, UT Southwestern Medical Center, Dallas, TX 75390, USA., Houlden H; UCL Institute of Neurology, Queen Square, London, WC1N 3BG, UK., Karch CM; Hope Center for Neurological Disorders, Washington University School of Medicine, St. Louis, MO 63110, USA.; Department of Psychiatry, Washington University School of Medicine, St. Louis, MO 63110, USA.; Knight Alzheimer's Disease Research Center, Washington University School of Medicine, St. Louis, MO 63110, USA., Bateman RJ; Tracy Family SILQ Center for Neurodegenerative Biology, St. Louis, MO 63110, USA.; Department of Neurology, Washington University School of Medicine, St. Louis, MO 63110, USA., Sato C; Tracy Family SILQ Center for Neurodegenerative Biology, St. Louis, MO 63110, USA.; Department of Neurology, Washington University School of Medicine, St. Louis, MO 63110, USA., Mennerick SJ; Department of Psychiatry, Washington University School of Medicine, St. Louis, MO 63110, USA., Diamond MI; Center for Alzheimer's and Neurodegenerative Diseases, Peter O'Donnell Jr. Brain Institute, UT Southwestern Medical Center, Dallas, TX 75390, USA., Kim J; Stark Neurosciences Research Institute, Indiana University School of Medicine, Indianapolis, IN 46202, USA.; Department of Medical and Molecular Genetics, Indiana University School of Medicine, Indianapolis, IN 46202, USA., Tanzi RE; Genetics and Aging Research Unit, MassGeneral Institute for Neurodegenerative Disease, McCance Center for Brain Health, Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA 02129, USA., Holtzman DM; Hope Center for Neurological Disorders, Washington University School of Medicine, St. Louis, MO 63110, USA.; Knight Alzheimer's Disease Research Center, Washington University School of Medicine, St. Louis, MO 63110, USA.; Department of Neurology, Washington University School of Medicine, St. Louis, MO 63110, USA., Yoo AS; Department of Developmental Biology, Washington University School of Medicine, St. Louis, MO 63110, USA.; Center for Regenerative Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA.; Hope Center for Neurological Disorders, Washington University School of Medicine, St. Louis, MO 63110, USA.

Publikováno v: Science (New York, N.Y.) [Science] 2024 Aug 02; Vol. 385 (6708), pp. adl2992. Date of Electronic Publication: 2024 Aug 02.

Neurodevelopment and Metabolism in the Maternal-Placental-Fetal Unit.

Autor: Parenti M; Department of Nutrition, University of California, Davis.; Now with Center for Developmental Biology and Regenerative Medicine, Seattle Children's Research Institute, Seattle, Washington., Schmidt RJ; Department of Public Health Sciences, University of California, Davis.; MIND Institute, University of California, Davis, Sacramento., Tancredi DJ; Department of Pediatrics, School of Medicine, University of California, Davis., Hertz-Picciotto I; Department of Public Health Sciences, University of California, Davis.; MIND Institute, University of California, Davis, Sacramento., Walker CK; MIND Institute, University of California, Davis, Sacramento.; Department of Obstetrics & Gynecology, School of Medicine, University of California, Davis, Sacramento., Slupsky CM; Department of Nutrition, University of California, Davis.; Department of Food Science and Technology, University of California, Davis.

Publikováno v: JAMA network open [JAMA Netw Open] 2024 May 01; Vol. 7 (5), pp. e2413399. Date of Electronic Publication: 2024 May 01.

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A Molecular Basis of Human Brain Connectivity.

Autor: Ng B, Tasaki S, Greathouse KM, Walker CK, Zhang A, Covitz S, Cieslak M, Adamson AB, Andrade JP, Poovey EH, Curtis KA, Muhammad HM, Seidlitz J, Satterthwaite T, Bennett DA, Seyfried NT, Vogel J, Gaiteri C, Herskowitz JH

Publikováno v: BioRxiv : the preprint server for biology [bioRxiv] 2023 Jul 24. Date of Electronic Publication: 2023 Jul 24.