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An integrated technology for quantitative wide mutational scanning of human antibody Fab libraries.

Autor: Petersen BM; Department of Chemical and Biological Engineering, University of Colorado Boulder, Boulder, CO, 80305, USA., Kirby MB; Department of Chemical and Biological Engineering, University of Colorado Boulder, Boulder, CO, 80305, USA., Chrispens KM; Department of Chemical and Biological Engineering, University of Colorado Boulder, Boulder, CO, 80305, USA., Irvin OM; Department of Chemical and Biological Engineering, University of Colorado Boulder, Boulder, CO, 80305, USA., Strawn IK; Department of Chemical and Biological Engineering, University of Colorado Boulder, Boulder, CO, 80305, USA., Haas CM; Department of Chemical and Biological Engineering, University of Colorado Boulder, Boulder, CO, 80305, USA., Walker AM; Department of Chemical and Biological Engineering, University of Colorado Boulder, Boulder, CO, 80305, USA., Baumer ZT; Department of Chemical and Biological Engineering, University of Colorado Boulder, Boulder, CO, 80305, USA., Ulmer SA; Department of Chemical and Biological Engineering, University of Colorado Boulder, Boulder, CO, 80305, USA., Ayala E; Department of Immunology and Microbiology, University of Colorado Anschutz Medical Campus, Aurora, CO 80045., Rhodes ER; Department of Chemical and Biological Engineering, University of Colorado Boulder, Boulder, CO, 80305, USA., Guthmiller JJ; Department of Immunology and Microbiology, University of Colorado Anschutz Medical Campus, Aurora, CO 80045., Steiner PJ; Department of Chemical and Biological Engineering, University of Colorado Boulder, Boulder, CO, 80305, USA., Whitehead TA; Department of Chemical and Biological Engineering, University of Colorado Boulder, Boulder, CO, 80305, USA.

Publikováno v: BioRxiv : the preprint server for biology [bioRxiv] 2024 Jan 16. Date of Electronic Publication: 2024 Jan 16.