Socioeconomic deprivation and mode-specific outcomes in patients with chronic heart failure

Autor: Witte, KK, Patel, PA, Walker, AMN, Schechter, CB, Drozd, M, Sengupta, A, Byrom, R, Kearney, LC, Sapsford, RJ, Kearney, MT, Cubbon, RM

Publikováno v: Heart

Objective: To characterise the association between socioeconomic deprivation and adverse outcomes in patients with chronic heart failure (CHF).\ud \ud \ud \ud Methods: We prospectively observed 1802 patients with CHF and left ventricular ejection fra

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::431c17ea03eb8261d17dea5ea007f097
http://europepmc.org/articles/PMC5992368

Novel Paracrine Action of Endothelium Enhances Glucose Uptake in Muscle and Fat.

Autor: Viswambharan H; Leeds Institute for Cardiovascular and Metabolic Medicine, University of Leeds, United Kingdom (H.V., N.Y.Y., H.I., K.B., N.J.H., A.S., K.E.H., E.R.C., V.K.G., P.C., K.J.S., N.M., Y.A., N.E., J.B., A.M.N.W., S.T.F., K.E.P., R.M.C., K.N., D.J.B., S.B.W., M.T.K., P.S.)., Yuldasheva NY; Leeds Institute for Cardiovascular and Metabolic Medicine, University of Leeds, United Kingdom (H.V., N.Y.Y., H.I., K.B., N.J.H., A.S., K.E.H., E.R.C., V.K.G., P.C., K.J.S., N.M., Y.A., N.E., J.B., A.M.N.W., S.T.F., K.E.P., R.M.C., K.N., D.J.B., S.B.W., M.T.K., P.S.)., Imrie H; Leeds Institute for Cardiovascular and Metabolic Medicine, University of Leeds, United Kingdom (H.V., N.Y.Y., H.I., K.B., N.J.H., A.S., K.E.H., E.R.C., V.K.G., P.C., K.J.S., N.M., Y.A., N.E., J.B., A.M.N.W., S.T.F., K.E.P., R.M.C., K.N., D.J.B., S.B.W., M.T.K., P.S.)., Bridge K; Leeds Institute for Cardiovascular and Metabolic Medicine, University of Leeds, United Kingdom (H.V., N.Y.Y., H.I., K.B., N.J.H., A.S., K.E.H., E.R.C., V.K.G., P.C., K.J.S., N.M., Y.A., N.E., J.B., A.M.N.W., S.T.F., K.E.P., R.M.C., K.N., D.J.B., S.B.W., M.T.K., P.S.)., Haywood NJ; Leeds Institute for Cardiovascular and Metabolic Medicine, University of Leeds, United Kingdom (H.V., N.Y.Y., H.I., K.B., N.J.H., A.S., K.E.H., E.R.C., V.K.G., P.C., K.J.S., N.M., Y.A., N.E., J.B., A.M.N.W., S.T.F., K.E.P., R.M.C., K.N., D.J.B., S.B.W., M.T.K., P.S.)., Skromna A; Leeds Institute for Cardiovascular and Metabolic Medicine, University of Leeds, United Kingdom (H.V., N.Y.Y., H.I., K.B., N.J.H., A.S., K.E.H., E.R.C., V.K.G., P.C., K.J.S., N.M., Y.A., N.E., J.B., A.M.N.W., S.T.F., K.E.P., R.M.C., K.N., D.J.B., S.B.W., M.T.K., P.S.)., Hemmings KE; Leeds Institute for Cardiovascular and Metabolic Medicine, University of Leeds, United Kingdom (H.V., N.Y.Y., H.I., K.B., N.J.H., A.S., K.E.H., E.R.C., V.K.G., P.C., K.J.S., N.M., Y.A., N.E., J.B., A.M.N.W., S.T.F., K.E.P., R.M.C., K.N., D.J.B., S.B.W., M.T.K., P.S.)., Clark ER; Leeds Institute for Cardiovascular and Metabolic Medicine, University of Leeds, United Kingdom (H.V., N.Y.Y., H.I., K.B., N.J.H., A.S., K.E.H., E.R.C., V.K.G., P.C., K.J.S., N.M., Y.A., N.E., J.B., A.M.N.W., S.T.F., K.E.P., R.M.C., K.N., D.J.B., S.B.W., M.T.K., P.S.)., Gatenby VK; Leeds Institute for Cardiovascular and Metabolic Medicine, University of Leeds, United Kingdom (H.V., N.Y.Y., H.I., K.B., N.J.H., A.S., K.E.H., E.R.C., V.K.G., P.C., K.J.S., N.M., Y.A., N.E., J.B., A.M.N.W., S.T.F., K.E.P., R.M.C., K.N., D.J.B., S.B.W., M.T.K., P.S.)., Cordell P; Leeds Institute for Cardiovascular and Metabolic Medicine, University of Leeds, United Kingdom (H.V., N.Y.Y., H.I., K.B., N.J.H., A.S., K.E.H., E.R.C., V.K.G., P.C., K.J.S., N.M., Y.A., N.E., J.B., A.M.N.W., S.T.F., K.E.P., R.M.C., K.N., D.J.B., S.B.W., M.T.K., P.S.)., Simmons KJ; Leeds Institute for Cardiovascular and Metabolic Medicine, University of Leeds, United Kingdom (H.V., N.Y.Y., H.I., K.B., N.J.H., A.S., K.E.H., E.R.C., V.K.G., P.C., K.J.S., N.M., Y.A., N.E., J.B., A.M.N.W., S.T.F., K.E.P., R.M.C., K.N., D.J.B., S.B.W., M.T.K., P.S.)., Makava N; Leeds Institute for Cardiovascular and Metabolic Medicine, University of Leeds, United Kingdom (H.V., N.Y.Y., H.I., K.B., N.J.H., A.S., K.E.H., E.R.C., V.K.G., P.C., K.J.S., N.M., Y.A., N.E., J.B., A.M.N.W., S.T.F., K.E.P., R.M.C., K.N., D.J.B., S.B.W., M.T.K., P.S.)., Abudushalamu Y; Leeds Institute for Cardiovascular and Metabolic Medicine, University of Leeds, United Kingdom (H.V., N.Y.Y., H.I., K.B., N.J.H., A.S., K.E.H., E.R.C., V.K.G., P.C., K.J.S., N.M., Y.A., N.E., J.B., A.M.N.W., S.T.F., K.E.P., R.M.C., K.N., D.J.B., S.B.W., M.T.K., P.S.)., Endesh N; Leeds Institute for Cardiovascular and Metabolic Medicine, University of Leeds, United Kingdom (H.V., N.Y.Y., H.I., K.B., N.J.H., A.S., K.E.H., E.R.C., V.K.G., P.C., K.J.S., N.M., Y.A., N.E., J.B., A.M.N.W., S.T.F., K.E.P., R.M.C., K.N., D.J.B., S.B.W., M.T.K., P.S.)., Brown J; Leeds Institute for Cardiovascular and Metabolic Medicine, University of Leeds, United Kingdom (H.V., N.Y.Y., H.I., K.B., N.J.H., A.S., K.E.H., E.R.C., V.K.G., P.C., K.J.S., N.M., Y.A., N.E., J.B., A.M.N.W., S.T.F., K.E.P., R.M.C., K.N., D.J.B., S.B.W., M.T.K., P.S.)., Walker AMN; Leeds Institute for Cardiovascular and Metabolic Medicine, University of Leeds, United Kingdom (H.V., N.Y.Y., H.I., K.B., N.J.H., A.S., K.E.H., E.R.C., V.K.G., P.C., K.J.S., N.M., Y.A., N.E., J.B., A.M.N.W., S.T.F., K.E.P., R.M.C., K.N., D.J.B., S.B.W., M.T.K., P.S.)., Futers ST; Leeds Institute for Cardiovascular and Metabolic Medicine, University of Leeds, United Kingdom (H.V., N.Y.Y., H.I., K.B., N.J.H., A.S., K.E.H., E.R.C., V.K.G., P.C., K.J.S., N.M., Y.A., N.E., J.B., A.M.N.W., S.T.F., K.E.P., R.M.C., K.N., D.J.B., S.B.W., M.T.K., P.S.)., Porter KE; Leeds Institute for Cardiovascular and Metabolic Medicine, University of Leeds, United Kingdom (H.V., N.Y.Y., H.I., K.B., N.J.H., A.S., K.E.H., E.R.C., V.K.G., P.C., K.J.S., N.M., Y.A., N.E., J.B., A.M.N.W., S.T.F., K.E.P., R.M.C., K.N., D.J.B., S.B.W., M.T.K., P.S.)., Cubbon RM; Leeds Institute for Cardiovascular and Metabolic Medicine, University of Leeds, United Kingdom (H.V., N.Y.Y., H.I., K.B., N.J.H., A.S., K.E.H., E.R.C., V.K.G., P.C., K.J.S., N.M., Y.A., N.E., J.B., A.M.N.W., S.T.F., K.E.P., R.M.C., K.N., D.J.B., S.B.W., M.T.K., P.S.)., Naseem K; Leeds Institute for Cardiovascular and Metabolic Medicine, University of Leeds, United Kingdom (H.V., N.Y.Y., H.I., K.B., N.J.H., A.S., K.E.H., E.R.C., V.K.G., P.C., K.J.S., N.M., Y.A., N.E., J.B., A.M.N.W., S.T.F., K.E.P., R.M.C., K.N., D.J.B., S.B.W., M.T.K., P.S.)., Shah AM; British Heart Foundation Centre of Research Excellence, King's College London (A.M.S.)., Beech DJ; Leeds Institute for Cardiovascular and Metabolic Medicine, University of Leeds, United Kingdom (H.V., N.Y.Y., H.I., K.B., N.J.H., A.S., K.E.H., E.R.C., V.K.G., P.C., K.J.S., N.M., Y.A., N.E., J.B., A.M.N.W., S.T.F., K.E.P., R.M.C., K.N., D.J.B., S.B.W., M.T.K., P.S.)., Wheatcroft SB; Leeds Institute for Cardiovascular and Metabolic Medicine, University of Leeds, United Kingdom (H.V., N.Y.Y., H.I., K.B., N.J.H., A.S., K.E.H., E.R.C., V.K.G., P.C., K.J.S., N.M., Y.A., N.E., J.B., A.M.N.W., S.T.F., K.E.P., R.M.C., K.N., D.J.B., S.B.W., M.T.K., P.S.)., Kearney MT; Leeds Institute for Cardiovascular and Metabolic Medicine, University of Leeds, United Kingdom (H.V., N.Y.Y., H.I., K.B., N.J.H., A.S., K.E.H., E.R.C., V.K.G., P.C., K.J.S., N.M., Y.A., N.E., J.B., A.M.N.W., S.T.F., K.E.P., R.M.C., K.N., D.J.B., S.B.W., M.T.K., P.S.)., Sukumar P; Leeds Institute for Cardiovascular and Metabolic Medicine, University of Leeds, United Kingdom (H.V., N.Y.Y., H.I., K.B., N.J.H., A.S., K.E.H., E.R.C., V.K.G., P.C., K.J.S., N.M., Y.A., N.E., J.B., A.M.N.W., S.T.F., K.E.P., R.M.C., K.N., D.J.B., S.B.W., M.T.K., P.S.).

Publikováno v: Circulation research [Circ Res] 2021 Sep 17; Vol. 129 (7), pp. 720-734. Date of Electronic Publication: 2021 Aug 21.

Endothelial Insulin Receptors Promote VEGF-A Signaling via ERK1/2 and Sprouting Angiogenesis.

Autor: Walker AMN; Leeds Institute of Cardiovascular and Metabolic Medicine, The University of Leeds, Leeds LS2 9JT, UK., Warmke N; Leeds Institute of Cardiovascular and Metabolic Medicine, The University of Leeds, Leeds LS2 9JT, UK., Mercer B; Leeds Institute of Cardiovascular and Metabolic Medicine, The University of Leeds, Leeds LS2 9JT, UK., Watt NT; Leeds Institute of Cardiovascular and Metabolic Medicine, The University of Leeds, Leeds LS2 9JT, UK., Mughal R; Leeds Institute of Cardiovascular and Metabolic Medicine, The University of Leeds, Leeds LS2 9JT, UK., Smith J; Leeds Institute of Cardiovascular and Metabolic Medicine, The University of Leeds, Leeds LS2 9JT, UK., Galloway S; Leeds Institute of Cardiovascular and Metabolic Medicine, The University of Leeds, Leeds LS2 9JT, UK., Haywood NJ; Leeds Institute of Cardiovascular and Metabolic Medicine, The University of Leeds, Leeds LS2 9JT, UK., Soomro T; Leeds Institute of Cardiovascular and Metabolic Medicine, The University of Leeds, Leeds LS2 9JT, UK.; Imperial College Ophthalmology Research Group, Western Eye Hospital, London NW1 5QH, UK., Griffin KJ; Leeds Institute of Cardiovascular and Metabolic Medicine, The University of Leeds, Leeds LS2 9JT, UK., Wheatcroft SB; Leeds Institute of Cardiovascular and Metabolic Medicine, The University of Leeds, Leeds LS2 9JT, UK., Yuldasheva NY; Leeds Institute of Cardiovascular and Metabolic Medicine, The University of Leeds, Leeds LS2 9JT, UK., Beech DJ; Leeds Institute of Cardiovascular and Metabolic Medicine, The University of Leeds, Leeds LS2 9JT, UK., Carmeliet P; Laboratory of Angiogenesis and Vascular Metabolism, Center for Cancer Biology, Vlaams Instituut voor Biotechnologie (VIB), Department of Oncology, University of Leuven, Leuven 3000, Belgium., Kearney MT; Leeds Institute of Cardiovascular and Metabolic Medicine, The University of Leeds, Leeds LS2 9JT, UK., Cubbon RM; Leeds Institute of Cardiovascular and Metabolic Medicine, The University of Leeds, Leeds LS2 9JT, UK.

Publikováno v: Endocrinology [Endocrinology] 2021 Aug 01; Vol. 162 (8).

Ischemic Heart Disease Modifies the Association of Atrial Fibrillation With Mortality in Heart Failure With Reduced Ejection Fraction.

Autor: Mercer BN; 1 Leeds Institute of Cardiovascular and Metabolic Medicine LIGHT Laboratories The University of Leeds United Kingdom., Koshy A; 1 Leeds Institute of Cardiovascular and Metabolic Medicine LIGHT Laboratories The University of Leeds United Kingdom., Drozd M; 1 Leeds Institute of Cardiovascular and Metabolic Medicine LIGHT Laboratories The University of Leeds United Kingdom., Walker AMN; 1 Leeds Institute of Cardiovascular and Metabolic Medicine LIGHT Laboratories The University of Leeds United Kingdom., Patel PA; 1 Leeds Institute of Cardiovascular and Metabolic Medicine LIGHT Laboratories The University of Leeds United Kingdom., Kearney L; 1 Leeds Institute of Cardiovascular and Metabolic Medicine LIGHT Laboratories The University of Leeds United Kingdom., Gierula J; 1 Leeds Institute of Cardiovascular and Metabolic Medicine LIGHT Laboratories The University of Leeds United Kingdom., Paton MF; 1 Leeds Institute of Cardiovascular and Metabolic Medicine LIGHT Laboratories The University of Leeds United Kingdom., Lowry JE; 1 Leeds Institute of Cardiovascular and Metabolic Medicine LIGHT Laboratories The University of Leeds United Kingdom., Kearney MT; 1 Leeds Institute of Cardiovascular and Metabolic Medicine LIGHT Laboratories The University of Leeds United Kingdom., Cubbon RM; 1 Leeds Institute of Cardiovascular and Metabolic Medicine LIGHT Laboratories The University of Leeds United Kingdom., Witte KK; 1 Leeds Institute of Cardiovascular and Metabolic Medicine LIGHT Laboratories The University of Leeds United Kingdom.

Publikováno v: Journal of the American Heart Association [J Am Heart Assoc] 2018 Oct 16; Vol. 7 (20), pp. e009770.

Mortality Reduction Associated With β-Adrenoceptor Inhibition in Chronic Heart Failure Is Greater in Patients With Diabetes.

Autor: Witte KK; Leeds Institute for Cardiovascular and Metabolic Medicine, University of Leeds, Leeds, U.K., Drozd M; Leeds Institute for Cardiovascular and Metabolic Medicine, University of Leeds, Leeds, U.K., Walker AMN; Leeds Institute for Cardiovascular and Metabolic Medicine, University of Leeds, Leeds, U.K., Patel PA; Leeds Institute for Cardiovascular and Metabolic Medicine, University of Leeds, Leeds, U.K., Kearney JC; Leeds Institute for Cardiovascular and Metabolic Medicine, University of Leeds, Leeds, U.K. m.t.kearney@leeds.ac.uk., Chapman S; Leeds Institute for Cardiovascular and Metabolic Medicine, University of Leeds, Leeds, U.K., Sapsford RJ; Cardiology Department, Leeds Teaching Hospitals NHS Trust, Leeds, U.K., Gierula J; Leeds Institute for Cardiovascular and Metabolic Medicine, University of Leeds, Leeds, U.K., Paton MF; Leeds Institute for Cardiovascular and Metabolic Medicine, University of Leeds, Leeds, U.K., Lowry J; Leeds Institute for Cardiovascular and Metabolic Medicine, University of Leeds, Leeds, U.K., Kearney MT; Leeds Institute for Cardiovascular and Metabolic Medicine, University of Leeds, Leeds, U.K. m.t.kearney@leeds.ac.uk., Cubbon RM; Leeds Institute for Cardiovascular and Metabolic Medicine, University of Leeds, Leeds, U.K.

Publikováno v: Diabetes care [Diabetes Care] 2018 Jan; Vol. 41 (1), pp. 136-142. Date of Electronic Publication: 2017 Oct 05.