Zobrazeno 1 - 10
of 389
pro vyhledávání: '"Waljit S. Dhillo"'
Autor:
Natalie Ertl, Edouard G. Mills, Matthew B. Wall, Layla Thurston, Lisa Yang, Sofiya Suladze, Tia Hunjan, Maria Phylactou, Bijal Patel, Paul A. Bassett, Jonathan Howard, Eugenii A. Rabiner, Ali Abbara, David Goldmeier, Alexander N. Comninos, Waljit S. Dhillo
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract Distressing low sexual desire, termed Hypoactive Sexual Desire Disorder (HSDD), affects approximately 10% of women and 8% of men. In women, the ‘top-down’ theory of HSDD describes hyperactivity in higher-level cognitive brain regions, su
Externí odkaz:
https://doaj.org/article/383f163226e14ae28bdd068e1c689e99
Autor:
Simon Hanassab, Ali Abbara, Arthur C. Yeung, Margaritis Voliotis, Krasimira Tsaneva-Atanasova, Tom W. Kelsey, Geoffrey H. Trew, Scott M. Nelson, Thomas Heinis, Waljit S. Dhillo
Publikováno v:
npj Digital Medicine, Vol 7, Iss 1, Pp 1-19 (2024)
Abstract Infertility affects 1-in-6 couples, with repeated intensive cycles of assisted reproductive technology (ART) required by many to achieve a desired live birth. In ART, typically, clinicians and laboratory staff consider patient characteristic
Externí odkaz:
https://doaj.org/article/ba37042b7d6c445f9423067108a2f6f1
Autor:
Lin Zhang, Ronald W.H. Verwer, Joop van Heerikhuize, Paul J. Lucassen, Peter W. Nathanielsz, Elly M. Hol, Eleonora Aronica, Waljit S. Dhillo, Gerben Meynen, Dick F. Swaab
Publikováno v:
Acta Neuropathologica Communications, Vol 12, Iss 1, Pp 1-14 (2024)
Abstract The human hypothalamus modulates mental health by balancing interactions between hormonal fluctuations and stress responses. Stress-induced progesterone release activates progesterone receptors (PR) in the human brain and triggers alteration
Externí odkaz:
https://doaj.org/article/f3ec194bdc2c4ca6b6f0a9737f68b276
Autor:
Bonnie Grant, Joseph Kean, Naim Vali, John Campbell, Lorraine Maden, Prun Bijral, Waljit S. Dhillo, James McVeigh, Richard Quinton, Channa N. Jayasena
Publikováno v:
Substance Abuse Treatment, Prevention, and Policy, Vol 18, Iss 1, Pp 1-8 (2023)
Abstract Background Anabolic–androgenic steroids (AAS) mimic the effects of testosterone and may include testosterone itself; they are used for body enhancement within the general population. AAS use has been linked with increased mortality, cardio
Externí odkaz:
https://doaj.org/article/019245d9c84f48bf9d7fcf26ce9754c4
Autor:
Jose M. Ramos-Pittol, Isabel Fernandes-Freitas, Alexandra Milona, Stephen M. Manchishi, Kara Rainbow, Brian Y. H. Lam, John A. Tadross, Anthony Beucher, William H. Colledge, Inês Cebola, Kevin G. Murphy, Irene Miguel-Aliaga, Giles S. H. Yeo, Waljit S. Dhillo, Bryn M. Owen
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-10 (2023)
Abstract Coupling the release of pituitary hormones to the developmental stage of the oocyte is essential for female fertility. It requires estrogen to restrain kisspeptin (KISS1)-neuron pulsatility in the arcuate hypothalamic nucleus, while also exe
Externí odkaz:
https://doaj.org/article/59195b68a82445d591a6b19294b35586
Autor:
Pei Chia Eng, Roberta Forlano, Tricia Tan, Pinelopi Manousou, Waljit S. Dhillo, Chioma Izzi-Engbeaya
Publikováno v:
JHEP Reports, Vol 5, Iss 10, Pp 100835- (2023)
Summary: Non-alcoholic fatty liver disease (NAFLD) is a major cause of liver disease worldwide, affecting up to 30% of adults. Progression to non-alcoholic steatohepatitis (NASH) is a key risk factor for cirrhosis, hepatocellular carcinoma and cardio
Externí odkaz:
https://doaj.org/article/b65ab81e2c2148f3b2f5f6de245a6c7c
Publikováno v:
Frontiers in Endocrinology, Vol 14 (2023)
Polycystic Ovary Syndrome (PCOS) is a highly prevalent and heterogenous endocrinopathy affecting 5-18% of women. Although its cardinal features include androgen excess, ovulatory dysfunction, and/or polycystic ovarian morphology, women often display
Externí odkaz:
https://doaj.org/article/3ed976580f8e4a9db0310823c20a8939
Autor:
Maria Phylactou, Alexander N. Comninos, Ahmed Salih, Marina Labib, Pei Chia Eng, Sophie A. Clarke, Pope Moore, Tricia Tan, Jaimini Cegla, Waljit S. Dhillo, Ali Abbara
Publikováno v:
Frontiers in Endocrinology, Vol 14 (2023)
BackgroundFree ionized calcium (Ca2+) is the biologically active component of total calcium (TCa) and hence responsible for its biological action. TCa is routinely adjusted for albumin using several formulae (e.g. James, Orell, Payne and Berry) to mo
Externí odkaz:
https://doaj.org/article/6160053750e44b1e97c4dc5365611ee9
Autor:
Ludovica Cotellessa, Federica Marelli, Paolo Duminuco, Michela Adamo, Georgios E. Papadakis, Lucia Bartoloni, Naoko Sato, Mariarosaria Lang-Muritano, Amineh Troendle, Waljit S. Dhillo, Annamaria Morelli, Giulia Guarnieri, Nelly Pitteloud, Luca Persani, Marco Bonomi, Paolo Giacobini, Valeria Vezzoli
Publikováno v:
JCI Insight, Vol 8, Iss 5 (2023)
In vertebrate species, fertility is controlled by gonadotropin-releasing hormone (GnRH) neurons. GnRH cells arise outside the central nervous system, in the developing olfactory pit, and migrate along olfactory/vomeronasal/terminal nerve axons into t
Externí odkaz:
https://doaj.org/article/c1634bb787e84c16978962556f0101a1
Autor:
Ali Abbara, Bijal Patel, Isha Parekh, Akanksha Garg, Channa N. Jayasena, Alexander N. Comninos, Waljit S. Dhillo
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
IntroductionOvarian Hyperstimulation Syndrome (OHSS) is a life-threatening iatrogenic complication of In vitro fertilisation (IVF). This study aimed to quantify rates of Ovarian Hyperstimulation Syndrome (OHSS) requiring intensive care unit (ICU) adm
Externí odkaz:
https://doaj.org/article/999fed3e442948328502c39b50b9250f