Zobrazeno 1 - 10
of 141
pro vyhledávání: '"Waliul I. Khan"'
Publikováno v:
Pathogens, Vol 13, Iss 8, p 608 (2024)
Intestinal parasites, including helminths and protozoa, account for a significant portion of the global health burden. The gastrointestinal (GI) tract not only serves as the stage for these parasitic infections but also as the residence for millions
Externí odkaz:
https://doaj.org/article/41513382a1534af8840ddf1b11921a66
Autor:
Yun Han Kwon, Suhrid Banskota, Huaqing Wang, Laura Rossi, Jensine A. Grondin, Saad A. Syed, Yeganeh Yousefi, Jonathan D. Schertzer, Katherine M. Morrison, Michael G. Wade, Alison C. Holloway, Michael G. Surette, Gregory R. Steinberg, Waliul I. Khan
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-18 (2022)
Abstract Chemicals in food are widely used leading to significant human exposure. Allura Red AC (AR) is a highly common synthetic colorant; however, little is known about its impact on colitis. Here, we show chronic exposure of AR at a dose found in
Externí odkaz:
https://doaj.org/article/e22bc7fbc4f04c989edfbdc65e3e4ed2
Publikováno v:
Journal of Clinical Virology Plus, Vol 3, Iss 1, Pp 100131- (2023)
Background: Measles, mumps, rubella, and varicella-zoster (MMRV) immunity testing is important in occupational screening of healthcare workers and at-risk populations. Objectives: The goal of this study was to compare the performance of the Bio-Rad B
Externí odkaz:
https://doaj.org/article/4eaf986968ea4827aafa12492efa396f
Autor:
Yun Han Kwon, Suhrid Banskota, Huaqing Wang, Laura Rossi, Jensine A. Grondin, Saad A. Syed, Yeganeh Yousefi, Jonathan D. Schertzer, Katherine M. Morrison, Michael G. Wade, Alison C. Holloway, Michael G. Surette, Gregory R. Steinberg, Waliul I. Khan
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-1 (2023)
Externí odkaz:
https://doaj.org/article/980b7271ae484db98ed373f034b78d87
Inhibition of NADPH Oxidase (NOX) 2 Mitigates Colitis in Mice with Impaired Macrophage AMPK Function
Autor:
Suhrid Banskota, Huaqing Wang, Yun Han Kwon, Jaya Gautam, Sabah Haq, Jensine Grondin, Gregory R. Steinberg, Waliul I. Khan
Publikováno v:
Biomedicines, Vol 11, Iss 5, p 1443 (2023)
Macrophage adenosine monophosphate-activated protein kinase (AMPK) limits the development of experimental colitis. AMPK activation inhibits NADPH oxidase (NOX) 2 expression, reactive oxygen species (ROS) generation, and pro-inflammatory cytokine secr
Externí odkaz:
https://doaj.org/article/80d70e7b078c42febac98761d72c6475
Autor:
Zainab Taleb, Vania Carmona-Alcocer, Kyle Stokes, Marta Haireek, Huaqing Wang, Stephen M. Collins, Waliul I. Khan, Phillip Karpowicz
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 12 (2022)
Many physiological functions exhibit circadian rhythms: oscillations in biological processes that occur in a 24-hour period. These daily rhythms are maintained through a highly conserved molecular pacemaker known as the circadian clock. Circadian dis
Externí odkaz:
https://doaj.org/article/f91dd03a08294ff8b2eb724aa0e48f41
Autor:
Julian M. Yabut, Eric M. Desjardins, Eric J. Chan, Emily A. Day, Julie M. Leroux, Bo Wang, Elizabeth D. Crane, Wesley Wong, Katherine M. Morrison, Justin D. Crane, Waliul I. Khan, Gregory R. Steinberg
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
Serotonin inhibits adipose tissue thermogenesis. Here the authors show that obese mice housed in thermoneutrality have increased mast cell serotonin synthesis, and that inhibiting this pathway through deletion of mast cell Tph1 increases white adipos
Externí odkaz:
https://doaj.org/article/b41caca977ab47c4b862d4ee101f56a3
Publikováno v:
Journal of Biomedical Science, Vol 26, Iss 1, Pp 1-14 (2019)
Abstract The intestinal mucosa is a site of multiple stressors and forms the barrier between the internal and external environment. In the intestine, a complex interplay between the microbiota, epithelial barrier and the local immune system maintains
Externí odkaz:
https://doaj.org/article/6888117e58204614913f87a42963b24d
Autor:
Yun Han Kwon, Huaqing Wang, Emmanuel Denou, Jean-Eric Ghia, Laura Rossi, Michelle E. Fontes, Steve P. Bernier, Md. Sharif Shajib, Suhrid Banskota, Stephen M. Collins, Michael G. Surette, Waliul I. Khan
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 7, Iss 4, Pp 709-728 (2019)
Background & Aims: Serotonin (5-hydroxytryptamine [5-HT]) is synthesized mainly within enterochromaffin (EC) cells in the gut, and tryptophan hydroxylase 1 (Tph1) is the rate-limiting enzyme for 5-HT synthesis in EC cells. Accumulating evidence sugge
Externí odkaz:
https://doaj.org/article/277aef30894e466383b247fb23fca29b
Autor:
Kyle Stokes, Malika Nunes, Chantelle Trombley, Danilo E.F. L. Flôres, Gang Wu, Zainab Taleb, Abedalrhman Alkhateeb, Suhrid Banskota, Chris Harris, Oliver P. Love, Waliul I. Khan, Luis Rueda, John B. Hogenesch, Phillip Karpowicz
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 12, Iss 5, Pp 1847-1872.e0 (2021)
Background & Aims: Circadian rhythms are daily physiological oscillations driven by the circadian clock: a 24-hour transcriptional timekeeper that regulates hormones, inflammation, and metabolism. Circadian rhythms are known to be important for healt
Externí odkaz:
https://doaj.org/article/ab5c749e56d34683944b22691e2cbd1f