Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Walid M. Ghorab"'
Autor:
Aiten M. Soliman, Walid M. Ghorab, Dina M. Lotfy, Heba M. Karam, Mostafa M. Ghorab, Laila A. Ramadan
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-18 (2023)
Abstract In a search for new antioxidants, a set of new iodoquinazolinone derivatives bearing benzenesulfonamide moiety and variable acetamide pharmacophores 5–17 were designed and synthesized. The structures of the synthesized compounds were confi
Externí odkaz:
https://doaj.org/article/d74f7d4abd9b4a789c657a07ac8fd837
Publikováno v:
Journal of Molecular Structure. 1273:134358
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6ece6b5170a021e178d891796f008446
https://doi.org/10.1016/j.molstruc.2022.134358
https://doi.org/10.1016/j.molstruc.2022.134358
Publikováno v:
Bioorganic Chemistry. 131:106310
A set of novel N-substituted-2-((4-oxo-3-phenyl-3,4-dihydroquinazolin-2-yl)thio)acetamide 3-16 were designed and synthesized from 2-mercapto-3-phenylquinazolinone 2. The targeted compounds were screened for their cytotoxic activity against the hepato
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a2f37eb128854c2dd39de52fea70b09
https://doi.org/10.1016/j.bioorg.2022.106310
https://doi.org/10.1016/j.bioorg.2022.106310
Publikováno v:
Bioorganic chemistry. 80
Two series of 2-aminopyridine derivatives 6-17 and tyrphostin AG17 analogs 18-22 bearing 4-methylbenzenesulfonamide moiety were designed and synthesized as anticancer compounds. The synthesized compounds were biologically evaluated for their cytotoxi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90f4233ee04295c3b8e3fb593e096a3e
https://pubmed.ncbi.nlm.nih.gov/29966874
https://pubmed.ncbi.nlm.nih.gov/29966874
Publikováno v:
Journal of Heterocyclic Chemistry. 48:1269-1279
Quinoline derivatives posses many types of biological activities and have been reported to show significant anticancer activity. There is a variety of mechanisms for the anticancer activity and the most distinguished mechanism is the inhibition of va
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f0fbd03ff38840c9bee425e9ccd4163b
https://doi.org/10.1002/jhet.749
https://doi.org/10.1002/jhet.749
Publikováno v:
ChemInform. 43
A variety of novel quinoline and pyrimidoquinoline derivatives (XVI) is synthesized from enaminone (I), and evaluated for in vitro effects against the human cancer cell line MCF7.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::993ec5e4fc497ed86782cc3e58975f7a
https://doi.org/10.1002/chin.201216155
https://doi.org/10.1002/chin.201216155
Publikováno v:
Archives of pharmacal research. 35(8)
New quinoline derivatives 6, 7 and 19, pyrimidoquinoline derivatives 8-16 and triazolopyrimidoquinoline derivatives 17 and 18 bearing a bromo-substituent were synthesized starting from 3-(4-Bromophenylamino)-5,5-dimethylcyclohex-2-enone 3. All the ne
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f20530c2dea5f6184a5ff4aedbf067c7
https://pubmed.ncbi.nlm.nih.gov/22941476
https://pubmed.ncbi.nlm.nih.gov/22941476