Zobrazeno 1 - 10
of 80
pro vyhledávání: '"Walid Al-Achkar"'
Autor:
Yahia Moualla, Faten Moassass, Bassel AL-Halabi, Walid Al-achkar, Michael Georgeos, Haissam Yazigi, Atieh Khamis
Publikováno v:
Heliyon, Vol 8, Iss 11, Pp e11858- (2022)
The FMS-like tyrosine kinase-3 internal tandem duplication (FLT3-ITD) is one of the most prevalent mutations, affecting between 20 and 30 percent of cases in patients with acute myeloid leukemia (AML). The Patients with a FLT3-ITD mutation have a poo
Externí odkaz:
https://doaj.org/article/420d0b6859544bc5b0fa6d040aab8528
Autor:
Ismael F. Alarbeed, Abdulsamad Wafa, Faten Moassass, Bassel Al-Halabi, Walid Al-Achkar, Thomas Liehr, Imad Aboukhamis
Publikováno v:
Journal of Medical Case Reports, Vol 15, Iss 1, Pp 1-7 (2021)
Abstract Background Approximately 30% of adult acute myeloid leukemia (AML) acquire within fms-like tyrosine kinase 3 gene (FLT3) internal tandem duplications (FLT3/ITDs) in their juxtamembrane domain (JMD). FLT3/ITDs range in size from three to hund
Externí odkaz:
https://doaj.org/article/2da18d972cd0489486ae1027fa2a8e3e
Autor:
Abdulsamad Wafa, Belal Ali, Faten Moassass, Maged Kheder, Abdulmunim Aljapawe, Bassel Al‐Halabi, Kristin Mrasek, Thomas Liehr, Walid Al‐Achkar
Publikováno v:
Molecular Genetics & Genomic Medicine, Vol 10, Iss 2, Pp n/a-n/a (2022)
Abstract Background Familial cases of adult acute myeloid leukemia (AML) with germline‐mutated CCAAT/enhancer‐binding protein‐α (CEBPA) gene are a rare entity classified in World Health Organization (WHO) classification 2016. Most families rep
Externí odkaz:
https://doaj.org/article/451c50678499464b97dab51cb8dea3ce
Autor:
Abdulsamad Wafa, Rami A. Jarjour, Doaa Alolabi, Thomas Liehr, Othman Hamdan, Joana B. Melo, Isabel M. Carreira, Moneeb A. K. Othman, Walid Al-Achkar
Publikováno v:
Molecular Cytogenetics, Vol 13, Iss 1, Pp 1-6 (2020)
Abstract Background B cell precursor acute lymphoblastic leukemia (B-ALL) is the most common malignancy of childhood, with, after corresponding treatment, an overall complete remission rate of 90%. Approximately 75% of B-ALL cases harbor recurrent ab
Externí odkaz:
https://doaj.org/article/065fe71f6f684913b1454029df698cf4
Autor:
Abdulsamad Wafa, Rami A. Jarjour, Abdulmunim Aljapawe, Suher ALmedania, Thomas Liehr, Joana B. Melo, Isabel M. Carreira, Moneeb A. K. Othman, Walid Al-Achkar
Publikováno v:
Molecular Cytogenetics, Vol 13, Iss 1, Pp 1-6 (2020)
Abstract Background About 25 years ago, the acquired chromosome abnormality dicentric dic(9;20)(p11 ~ 13;q11) was seen described as a non-random aberration in B-cell precursor acute lymphoblastic leukemia (BCP-ALL). Yet, about 200 cases were reported
Externí odkaz:
https://doaj.org/article/85791fde35d048e18bca23dd84b3ec80
Publikováno v:
Middle East Fertility Society Journal, Vol 20, Iss 2, Pp 91-96 (2015)
Background: Premature ovarian failure (POF) is a primary ovarian defect characterized by absent menarche or premature depletion of ovarian follicles. Bone morphogenetic protein 15 (BMP15) is an oocyte-derived growth factor acting as a major player in
Externí odkaz:
https://doaj.org/article/8bbd16715463461faa6dae94fbc6ca13
Autor:
Abdulsamad Wafa, Bassel Al-Halabi, Imad Aboukhamis, Ismael F Al-Arbeed, Walid Al-Achkar, Faten Moassass
Publikováno v:
Asian Pacific Journal of Cancer Prevention. 22:3245-3251
Objective Activating mutations of the fms-like tyrosine kinase 3 gene (FLT3) by internal tandem duplications (ITDs) in the juxtamembrane domain (JMD) have been reported in ~30% of adult acute myeloid leukemia (AML) patients with cytogenetically norma
Autor:
Faten Moassass, Ismael F Al-Arbeed, Abdulsamad Wafa, Walid Al-Achkar, Bassel Al-Halabi, Imad Aboukhamis
Publikováno v:
Asian Pacific Journal of Cancer Prevention : APJCP
Objective Somatic mutations in exon 12 of the NPM1 gene is one of the most common genetic abnormalities in adult acute myeloid leukemia (AML), which is observed in 25-35% of AML patients and in 50-60% of patients with cytogenetically normal AML (CN-A
Autor:
Moneeb A.K. Othman, Doaa Alolabi, Abdulsamad Wafa, Isabel M. Carreira, Walid Al-Achkar, Othman Hamdan, Thomas Liehr, Joana B. Melo, Rami A. Jarjour
Publikováno v:
Molecular Cytogenetics, Vol 13, Iss 1, Pp 1-6 (2020)
Molecular Cytogenetics
Molecular Cytogenetics
Background B cell precursor acute lymphoblastic leukemia (B-ALL) is the most common malignancy of childhood, with, after corresponding treatment, an overall complete remission rate of 90%. Approximately 75% of B-ALL cases harbor recurrent abnormaliti
Autor:
Yahia Moualla, Faten Moassass, Bassel AL-Halbi, Walid Al -Achkar, Michael Georgeos, Haissam Yazigi, Atieh Khamis
Publikováno v:
Asian Pacific journal of cancer prevention : APJCP. 23(4)
Among all types of hematological neoplasms, acute myeloid leukemia (AML) has the highest death rate. Recently, cytogenetic and molecular genetics are crucial in the management, as a consequence of their effect on AML pathogenesis, classification, ris