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Autor:
Henrik Strahl, Patrick F. Chinnery, Gavin Hudson, Naoko Irie, Wei Wei, Dusko Ilic, Antonio Capalbo, Jonathan Coxhead, Yacoub Khalaf, Brendan A I Payne, Moira Crosier, Walfred C. W. Tang, Laila Noli, Angela Pyle, Vasileios I. Floros, M. Azim Surani, Sabine Dietmann, Mitinori Saitou
Publikováno v:
Nature cell biology. 20(2)
Mitochondrial DNA (mtDNA) mutations cause inherited diseases and are implicated in the pathogenesis of common late-onset disorders, but how they arise is not clear1,2. Here we show mtDNA mutations are present in primordial germ cells (PGCs) within he