Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Waleed S. Al Amri"'
Autor:
Diana E. Baxter, Lisa M. Allinson, Waleed S. Al Amri, James A. Poulter, Arindam Pramanik, James L. Thorne, Eldo T. Verghese, Thomas A. Hughes
Publikováno v:
Cancers, Vol 13, Iss 23, p 5979 (2021)
Background: poor prognosis primary breast cancers are typically treated with cytotoxic chemotherapy. However, recurrences remain relatively common even after this aggressive therapy. Comparison of matched tumours pre- and post-chemotherapy can allow
Externí odkaz:
https://doaj.org/article/73089cca0f174b1bb8af28e0d8fe2eac
Autor:
Thomas A. Hughes, Eldo T. Verghese, Lucy F. Stead, Abeer M. Shaaban, Stacey J. Jones, Andrew M. Hanby, Sandra M. Bell, Diana E. Baxter, Lisa M. Allinson, Waleed S. Al Amri
Somatic variants data
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ce2c36ece86566607889e955ffc1494
https://doi.org/10.1158/1535-7163.22519098
https://doi.org/10.1158/1535-7163.22519098
Autor:
Thomas A. Hughes, Eldo T. Verghese, Lucy F. Stead, Abeer M. Shaaban, Stacey J. Jones, Andrew M. Hanby, Sandra M. Bell, Diana E. Baxter, Lisa M. Allinson, Waleed S. Al Amri
Supplementary information concerning: laser capture microscopy (Fig S1), efficiency of siRNA knock-down (Fig S2), results of siRNA knock-down for ABC gene expression and function (Fig S3), abilities of MUC17 and PCNX1 expression to define patient out
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29ac275e135431d4023f6231a8156b5e
https://doi.org/10.1158/1535-7163.22519101
https://doi.org/10.1158/1535-7163.22519101
Autor:
Thomas A. Hughes, Eldo T. Verghese, Lucy F. Stead, Abeer M. Shaaban, Stacey J. Jones, Andrew M. Hanby, Sandra M. Bell, Diana E. Baxter, Lisa M. Allinson, Waleed S. Al Amri
Poor-prognosis breast cancers are treated with cytotoxic chemotherapy, but often without any guidance from therapy predictive markers because universally accepted markers are not currently available. Treatment failure, in the form of recurrences, is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5cb3f015b5b0902de52081c2c0ffebcc
https://doi.org/10.1158/1535-7163.c.6542289
https://doi.org/10.1158/1535-7163.c.6542289
Autor:
Lucy F. Stead, Abeer M Shaaban, Stacey J. Jones, Lisa M. Allinson, Thomas A. Hughes, Sandra M. Bell, Andrew M. Hanby, Waleed S. Al Amri, Diana E. Baxter, Eldo T. Verghese
Publikováno v:
Molecular Cancer Therapeutics. 19:945-955
Poor-prognosis breast cancers are treated with cytotoxic chemotherapy, but often without any guidance from therapy predictive markers because universally accepted markers are not currently available. Treatment failure, in the form of recurrences, is
Autor:
Waleed S. Al Amri, William E. Hughes, James L. Thorne, Geoff Wells, Ian M. Carr, Brian V Hogan, Thomas A. Hughes, Fiona Langlands, Arindam Pramanik, Layla K. Younis, Stacey J. Jones, Sarah A. Harris, Eldo T. Verghese, Rebecca Millican-Slater, Nevine M.F. El Deeb, Mervat A. Hamza, Baek Kim, Noha Gwili
Publikováno v:
British Journal of Cancer
Background Breast cancer stem cells (BCSCs) are drivers of therapy-resistance, therefore are responsible for poor survival. Molecular signatures of BCSCs from primary cancers remain undefined. Here, we identify the consistent transcriptome of primary
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99a64defdd7881cec05092b3963a5ac9
https://eprints.whiterose.ac.uk/174958/7/s41416-021-01484-w.pdf
https://eprints.whiterose.ac.uk/174958/7/s41416-021-01484-w.pdf
Autor:
Thomas A. Hughes, James A. Poulter, Lisa M. Allinson, Arindam Pramanik, Diana E. Baxter, Eldo T. Verghese, James L. Thorne, Waleed S. Al Amri
Publikováno v:
Cancers, Vol 13, Iss 5979, p 5979 (2021)
Cancers
Cancers; Volume 13; Issue 23; Pages: 5979
Cancers
Cancers; Volume 13; Issue 23; Pages: 5979
Simple Summary The resistance of cancer cells to cytotoxic chemotherapy limits cure rates in breast cancer, and a better understanding of resistance mechanisms will aid design of strategies to improve treatments. We have identified molecules that cau
Autor:
Diana E. Baxter, Eldo T. Verghese, Andrew M. Hanby, James L. Thorne, Lucy F. Stead, Thomas A. Hughes, Waleed S. Al Amri
Publikováno v:
Breast Cancer Research and Treatment
Purpose More than a third of primary breast cancer patients are treated with cytotoxic chemotherapy, typically without guidance from predictive markers. Increased use of neoadjuvant chemotherapy provides opportunities for identification of molecules