Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Waleed M. Elhelaly"'
Autor:
Nicholas T. Lam, Ngoc Uyen Nhi Nguyen, Mahmoud Salama Ahmed, Ching-Cheng Hsu, Pamela E. Rios Coronado, Shujuan Li, Ivan Menendez-Montes, Suwannee Thet, Waleed M. Elhelaly, Feng Xiao, Xiaoyu Wang, Noelle S. Williams, Diana C. Canseco, Kristy Red-Horse, Beverly A. Rothermel, Hesham A. Sadek
Publikováno v:
Nature Cardiovascular Research. 1:679-688
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::181beb01913108952a06208ce301ad21
https://doi.org/10.1038/s44161-022-00098-6
https://doi.org/10.1038/s44161-022-00098-6
Autor:
Chukwuemeka George Anene-Nzelu, Michael Kinter, Hesham A. Sadek, Jainy J. Savla, Salim Abdisalaam, Luke I. Szweda, Abdallah Elnwasany, Roger Foo, Ursa Bezan Petric, Ana Helena Macedo Pereira, Ivan Menendez-Montes, Mohammed Kanchwala, Chalermchai Khemtong, Yuji Nakada, Wilson Lek Wen Tan, Shujuan Li, Craig R. Malloy, Mahmoud S. Ahmed, Kaitlyn M. Eckert, Ngoc Uyen Nhi Nguyen, A. Dean Sherry, Emily L Ensley, Aroumougame Asaithamby, Gaurav Sharma, Gonçalo Vale, Chao Xing, Linzhang Huang, Matthew A. Mitsche, Nicholas T. Lam, Philip W. Shaul, Alisson C. Cardoso, Joseph A. Hill, Waleed M. Elhelaly, Jeffrey G. McDonald
Publikováno v:
Nature Metabolism. 2:167-178
The neonatal mammalian heart is capable of regeneration for a brief window of time after birth. However, this regenerative capacity is lost within the first week of life, which coincides with a postnatal shift from anaerobic glycolysis to mitochondri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::42c21436855a1b7e902d0de5305b7349
https://doi.org/10.1038/s42255-020-0169-x
https://doi.org/10.1038/s42255-020-0169-x
Autor:
Ivan Menendez-Montes, Zhaoning Wang, Alisson C. Cardoso, Andrew Lemoff, Miao Cui, Mohammad Goodarzi, John M. Shelton, Ngoc Uyen Nhi Nguyen, Ana Helena Macedo Pereira, Shujuan Li, Shah R. Ali, Feng Xiao, Waleed M. Elhelaly, Nicholas T. Lam, Abdallah Elnwasany, Michael Kinter, Hesham A. Sadek, Wataru Kimura, Suwannee Thet, Luke I. Szweda
To identify non-cell-autonomous effectors of cardiomyocyte mitosis, we analyzed a transcriptomic screen of regenerating and non-regenerating neonatal hearts for differentially-expressed secreted proteins – which we hypothesized could include candid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::868ea862c7969bb49863246fb5285e55
https://doi.org/10.1101/2021.09.16.460522
https://doi.org/10.1101/2021.09.16.460522
Autor:
Craig R. Malloy, Xiang Luo, Charles D. Smart, Jun Lin, Lin Tan, Yu An, Philipp E. Scherer, Qinfeng Li, Chongshan Dai, Luke I. Szweda, Guihao Chen, Thomas G. Gillette, Guangyu Zhang, Meihui Wang, Yingfeng Deng, Shangang Zhao, Guosheng Fu, Gaurav Sharma, Yingchao Gong, Jason W. Locasale, Chao Li, Zhao V. Wang, Shawn M. Davidson, Waleed M. Elhelaly, Philip L. Lorenzi, Abdallah Elnwasany, Matthew G. Vander Heiden, Juan Liu, Shuang Jie Lv
Publikováno v:
Circulation
Background: Metabolic remodeling precedes most alterations during cardiac hypertrophic growth under hemodynamic stress. The elevation of glucose utilization has been recognized as a hallmark of metabolic remodeling. However, its role in cardiac hyper
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31df6c19c6fb338b61629372b20d1bc0
https://pubmed.ncbi.nlm.nih.gov/34102853
https://pubmed.ncbi.nlm.nih.gov/34102853
Autor:
Chao Xing, Ping Wang, Diana C. Canseco, Ngoc Uyen Nhi Nguyen, Nicholas T. Lam, Shujuan Li, Feng Xiao, Suwannee Thet, Roger J. Hajjar, Mohammed Kanchwala, Xiang Luo, Wataru Kimura, Rohit Singh, Hesham A. Sadek, Waleed M. Elhelaly, Sakthivel Sadayappan, Joseph A. Hill
Recent interest in understanding cardiomyocyte cell-cycle has been driven by potential therapeutic applications in cardiomyopathy. However, despite recent advances, cardiomyocyte mitosis remains a poorly understood process. For example, it is unclear
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1d5368f8399f352c0fa872368a46028f
https://doi.org/10.1101/2020.12.24.424022
https://doi.org/10.1101/2020.12.24.424022
Autor:
Roy Jagoree, Maimon E. Hubbi, Nicholas T. Lam, Shalini Muralidhar, Shujuan Li, Zhaoning Wang, Roger Foo, Wilson Lek Wen Tan, Beverly A. Rothermel, Jainy J. Savla, Ngoc Uyen Nhi Nguyen, Waleed M. Elhelaly, Diana C. Canseco, Suwannee Thet, Joseph A. Hill, Yuji Nakada, Shah R. Ali, Elisa Villalobos, Chukwuemeka George Anene-Nzelu, Mahmoud S. Ahmed, Feng Xiao, Jesung Moon, Hesham A. Sadek, Ivan Menendez-Montes, Martha S. Cyert
Publikováno v:
Circulation Research. 127
A major factor in the progression to heart failure in humans is the inability of the adult heart to repair itself after injury. Our group recently demonstrated that the early postnatal mammalian heart is capable of regeneration following injury throu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::42f4424c9f2d7449a12086bf6bb81a97
https://doi.org/10.1161/res.127.suppl_1.mp161
https://doi.org/10.1161/res.127.suppl_1.mp161
Autor:
Ngoc Uyen Nhi Nguyen, Shah R. Ali, Ivan Menendez-Montes, Hesham A. Sadek, Waleed M. Elhelaly, Suwannee Thet
Publikováno v:
Circulation Research. 127
Background: The adult mammalian heart is unable to regenerate after an injury. However, newborn mice are able to fully regenerate the heart after myocardial infarction (MI). The neonatal MI model therefore is a potential blueprint for regenerating th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7ae8beb2592f82243a98ae3039911204
https://doi.org/10.1161/res.127.suppl_1.527
https://doi.org/10.1161/res.127.suppl_1.527
Autor:
Alisson C, Cardoso, Nicholas T, Lam, Jainy J, Savla, Yuji, Nakada, Ana Helena M, Pereira, Abdallah, Elnwasany, Ivan, Menendez-Montes, Emily L, Ensley, Ursa Bezan, Petric, Gaurav, Sharma, A Dean, Sherry, Craig R, Malloy, Chalermchai, Khemtong, Michael T, Kinter, Wilson Lek Wen, Tan, Chukwuemeka George, Anene-Nzelu, Roger Sik-Yin, Foo, Ngoc Uyen Nhi, Nguyen, Shujuan, Li, Mahmoud Salama, Ahmed, Waleed M, Elhelaly, Salim, Abdisalaam, Aroumougame, Asaithamby, Chao, Xing, Mohammed, Kanchwala, Goncalo, Vale, Kaitlyn M, Eckert, Matthew A, Mitsche, Jeffrey G, McDonald, Joseph A, Hill, Linzhang, Huang, Philip W, Shaul, Luke I, Szweda, Hesham A, Sadek
Publikováno v:
Nature metabolism
The neonatal mammalian heart is capable of regeneration for a brief window of time after birth. However, this regenerative capacity is lost within the first week of life, which coincides with a postnatal shift from anaerobic glycolysis to mitochondri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::cb5bc6db53df74e64d78e4fb6d5dccb6
https://pubmed.ncbi.nlm.nih.gov/32617517
https://pubmed.ncbi.nlm.nih.gov/32617517
Autor:
Shalini Muralidhar, Martha S. Cyert, Jainy J. Savla, Shujuan Li, Jagoree Roy, Yuji Nakada, Maimon E. Hubbi, Beverly A. Rothermel, Roger Foo, Shah R. Ali, Wilson Lek Wen Tan, Mahmoud S. Ahmed, Feng Xiao, Jesung Moon, Kareem A. Zidan, Magid S. Mohamed, Ivan Menendez-Montes, Ngoc Uyen Nhi Nguyen, Hesham A. Sadek, Diana C. Canseco, Victoria Le, Chukwuemeka George Anene-Nzelu, Xun Meng, Suwannee Thet, Mohammed Kanchwala, Elisa Villalobos, Nicholas T. Lam, Chao Xing, Joseph A. Hill, Waleed M. Elhelaly, Zhaoning Wang, Victor Le, Hamed W. El-Feky
Publikováno v:
Nguyen, N U N, Canseco, D C, Xiao, F, Nakada, Y, Li, S, Lam, N T, Muralidhar, S A, Savla, J J, Hill, J A, Le, V, Zidan, K A, El-feky, H W, Wang, Z, Ahmed, M S, Hubbi, M E, Menendez-montes, I, Moon, J, Ali, S R, Le, V, Villalobos, E, Mohamed, M S, Elhelaly, W M, Thet, S, Anene-nzelu, C G, Tan, W L W, Foo, R S, Meng, X, Kanchwala, M, Xing, C, Roy, J, Cyert, M S, Rothermel, B A & Sadek, H A 2020, ' A calcineurin–Hoxb13 axis regulates growth mode of mammalian cardiomyocytes ', Nature, vol. 582, no. 7811, pp. 271-276 . https://doi.org/10.1038/s41586-020-2228-6
Nature
Nature
A major factor in the progression to heart failure in humans is the inability of the adult heart to repair itself after injury. We recently demonstrated that the early postnatal mammalian heart is capable of regeneration following injury through prol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::159c9a7761d7e144ce14b016c92808b2
https://www.pure.ed.ac.uk/ws/files/155195562/ppnature17051.pdf
https://www.pure.ed.ac.uk/ws/files/155195562/ppnature17051.pdf
Autor:
Nicholas T. Lam, Roger Foo, Wilson Lek Wen Tan, Ping Wang, Alisson C. Cardoso, Joseph A. Hill, Ana Helena Macedo Pereira, Hesham A. Sadek, Feng Xiao, Ivan Menendez-Montes, Shujuan Li, Chukwuemeka George Anene-Nzelu, Suwannee Thet, Ngoc Uyen Nhi Nguyen, Yuji Nakada, Waleed M. Elhelaly
Publikováno v:
Circulation. 141(22)
Background: Primary valvular heart disease is a prevalent cause of morbidity and mortality in both industrialized and developing countries. Although the primary consequence of valvular heart disease is myocardial dysfunction, treatment of valvular he
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7966e94a16ac25975a05613c1a4429c
https://pubmed.ncbi.nlm.nih.gov/32272846
https://pubmed.ncbi.nlm.nih.gov/32272846