Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Waled A. Shihata"'
Autor:
Daniel G. Donner, Jason E. Bloom, Waled A. Shihata, Aascha A. Brown, Rosalind Cook, Tsin Yee Tai, Gavin W. Lambert, Po-Yin Chu, William Chan, Dion Stub, Bing H. Wang, David M. Kaye
Publikováno v:
Resuscitation Plus, Vol 11, Iss , Pp 100292- (2022)
Background: Adrenaline is routinely administered during cardiac arrest resuscitation. Using a novel murine model of cardiac arrest, this study evaluates the effects of adrenaline use on survival and end-organ injury. Methods: A total of 58 mice, incl
Externí odkaz:
https://doaj.org/article/d09f0f90529e4e52a72e4373b06a70e4
Autor:
Danielle L. Michell, Waled A. Shihata, Karen L. Andrews, Nurul Aisha Zainal Abidin, Ann-Maree Jefferis, Amanda K. Sampson, Natalie G. Lumsden, Olivier Huet, Marie-Odile Parat, Garry L. Jennings, Robert G. Parton, Kevin J. Woollard, David M. Kaye, Jaye P. F. Chin-Dusting, Andrew J. Murphy
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Abstract The aetiology and progression of hypertension involves various endogenous systems, such as the renin angiotensin system, the sympathetic nervous system, and endothelial dysfunction. Recent data suggest that vascular inflammation may also pla
Externí odkaz:
https://doaj.org/article/89d56ef6af8740c7a60458ad31b61cc1
Autor:
Dragana Dragoljevic, Camilla Bertuzzo Veiga, Danielle L. Michell, Waled A. Shihata, Annas Al-Sharea, Geoffrey A. Head, Andrew J. Murphy, Michael J. Kraakman, Man K.S. Lee
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 139, Iss , Pp 111668- (2021)
Metabolic Syndrome (MetS) is a complex and multifactorial condition often characterised by obesity, hypertension, hyperlipidaemia, insulin resistance, glucose intolerance and fasting hyperglycaemia. Collectively, MetS can increase the risk of atheros
Externí odkaz:
https://doaj.org/article/8a1768f2b3d54c13b0d3b1ce9900b53c
Autor:
Man K. S. Lee, Annas Al-Sharea, Waled A. Shihata, Camilla Bertuzzo Veiga, Olivia D. Cooney, Andrew J. Fleetwood, Michelle C. Flynn, Ellen Claeson, Clovis S. Palmer, Graeme I. Lancaster, Darren C. Henstridge, John A. Hamilton, Andrew J. Murphy
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Monocytes in humans consist of 3 subsets; CD14+CD16− (classical), CD14+CD16+ (intermediate) and CD14dimCD16+ (non-classical), which exhibit distinct and heterogeneous responses to activation. During acute inflammation CD14+CD16− monocytes are sig
Externí odkaz:
https://doaj.org/article/877fdbb79e87480fa17aaf1845695887
Autor:
Annas Al-Sharea, Man K. S. Lee, Alexandra Whillas, Danielle L. Michell, Waled A. Shihata, Alyce J. Nicholls, Olivia D. Cooney, Michael J. Kraakman, Camilla Bertuzzo Veiga, Ann-Maree Jefferis, Kristy Jackson, Prabhakara R. Nagareddy, Gavin Lambert, Connie H. Y. Wong, Karen L. Andrews, Geoff A. Head, Jaye Chin-Dusting, Andrew J. Murphy
Publikováno v:
Haematologica, Vol 104, Iss 3 (2019)
Hypertension is a major, independent risk factor for atherosclerotic cardiovascular disease. However, this pathology can arise through multiple pathways, which could influence vascular disease through distinct mechanisms. An overactive sympathetic ne
Externí odkaz:
https://doaj.org/article/4e2a37be40d14ab48b844e3e3f467be4
Autor:
Belal Chami, Farjaneh Hossain, Thomas W. Hambly, Xiaoping Cai, Roshanak Aran, Genevieve Fong, Abigail Vellajo, Nathan J.J Martin, XiaoSuo Wang, Joanne M. Dennis, Arpeeta Sharma, Waled A. Shihata, Jaye P. F. Chin-Dusting, Judy B. de Haan, Alexandra Sharland, Carolyn L. Geczy, Ben Freedman, Paul K. Witting
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Elevated serum amyloid A (SAA) levels may promote endothelial dysfunction, which is linked to cardiovascular and renal pathologies. We investigated the effect of SAA on vascular and renal function in apolipoprotein E-deficient (ApoE−/−) mice. Mal
Externí odkaz:
https://doaj.org/article/3257a71d9f64427bad0e208aaa82518f
Publikováno v:
Frontiers in Pharmacology, Vol 8 (2017)
Fibrosis is a process of dysfunctional wound repair, described by a failure of tissue regeneration and excessive deposition of extracellular matrix, resulting in tissue scarring and subsequent organ deterioration. There are a broad range of stimuli t
Externí odkaz:
https://doaj.org/article/f3cd7599c44a4b1698f33f9bbff6b7ff
Autor:
Matthew Snelson, Gavin W. Lambert, Assam El-Osta, Grant R Drummond, D. Donner, Melinda T. Coughlan, Helen Kiriazis, Aanthony Vinh, Duncan Horlock, Charles R. Mackay, Waled A. Shihata, Hamdi A. Jama, Beverly Giam, Tim D. Spector, Chad Johnson, Mark Ziemann, Xiao-Jun Du, April Fiedler, Kirill Tsyganov, Francine Z. Marques, David M. Kaye, Sarah E. Phillips, Amrita Vijay, Ana M. Valdes
Publikováno v:
Circulation. 141:1393-1403
Background: High blood pressure (BP) continues to be a major, poorly controlled but modifiable risk factor for cardiovascular death. Among key Western lifestyle factors, a diet poor in fiber is associated with prevalence of high BP. The impact of lac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d845305bf9643f6cc325542326c127bc
https://doi.org/10.1161/circulationaha.119.043081
https://doi.org/10.1161/circulationaha.119.043081
Autor:
Hamdi A. Jama, Alexander R Pinto, Harikrishnan Kaipananickal, Francine Z Marques, Charles R. Mackay, Gabriella E. Farrugia, Ekaterina Salimova, Waled A. Shihata, Kate L. Weeks, Madeleine Paterson, Malathi I Dona, David M. Kaye, Michael E Nakai, Jun Okabe, Evany Dinakis, Assam El-Osta
Publikováno v:
Hypertension. 78
Dietary fibre is fermented by the gut microbiota and protects against the development of cardiovascular disease (CVD) through the production of gut microbial metabolites. We hypothesised dietary fibre intake during pregnancy may prevent the developme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a72e207ac6fc59e2cdc39afe91a4de97
https://doi.org/10.1161/hyp.78.suppl_1.mp37
https://doi.org/10.1161/hyp.78.suppl_1.mp37
Autor:
Melinda T. Coughlan, Waled A. Shihata, Louise M Burrell, Charles R. Mackay, Francine Z. Marques, Rikeish R. Muralitharan, Michael E Nakai, Matthew Snelson, David M. Kaye, Hamdi A. Jama, Chad Johnson, Evany Dinakis
Publikováno v:
Hypertension. 77
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5a99121272c6281fc076c5e47d91e14
https://doi.org/10.1161/hypertensionaha.121.17039
https://doi.org/10.1161/hypertensionaha.121.17039