Zobrazeno 1 - 10
of 78
pro vyhledávání: '"Waldo, Cerpa"'
Autor:
Juan E. Tichauer, Matías Lira, Waldo Cerpa, Juan A. Orellana, Juan C. Sáez, Maximiliano Rovegno
Publikováno v:
Biological Research, Vol 57, Iss 1, Pp 1-19 (2024)
Abstract Background Spreading depression (SD) is an intriguing phenomenon characterized by massive slow brain depolarizations that affect neurons and glial cells. This phenomenon is repetitive and produces a metabolic overload that increases secondar
Externí odkaz:
https://doaj.org/article/cecf7704615944e397882f67e90d7298
Publikováno v:
Stresses, Vol 4, Iss 1, Pp 1-13 (2023)
Alcohol is one of the most used legal drugs abused worldwide, and its consumption is associated with high mortality and morbidity rates. There is an increasing concern about the starting age of consumption of this drug since it has become evident tha
Externí odkaz:
https://doaj.org/article/72a074987bf143e0ac8ff3b22c4f3eb1
Autor:
Carla Álvarez-Ferradas, Mario Wellmann, Koyam Morales, Marco Fuenzalida, Waldo Cerpa, Nibaldo C. Inestrosa, Christian Bonansco
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 15 (2022)
Synapse unsilencing is an essential mechanism for experience-dependent plasticity. Here, we showed that the application of the ligand Wnt-5a converts glutamatergic silent synapses into functional ones by increasing both α-amino-3-hydroxy-5-methyl-4-
Externí odkaz:
https://doaj.org/article/1082d02777fb4dc8a7a9cef7fab67bd7
Publikováno v:
Biological Research, Vol 54, Iss 1, Pp 1-13 (2021)
Abstract Background Exo70 is a subunit of the greater exocyst complex, a collection of proteins that oversees cellular membrane addition and polarized exocytosis by acting as a tethering intermediate between the plasma membrane and newly synthesized
Externí odkaz:
https://doaj.org/article/108a0db03edb4b65a5341b881658abb5
Autor:
Sofía Espinoza, Sebastián B. Arredondo, Francisca Barake, Francisco Carvajal, Fernanda G. Guerrero, Fabian Segovia-Miranda, David M. Valenzuela, Ursula Wyneken, Alejandro Rojas-Fernández, Waldo Cerpa, Loreto Massardo, Lorena Varela-Nallar, Alfonso González
Publikováno v:
BMC Biology, Vol 18, Iss 1, Pp 1-17 (2020)
Abstract Background Cognitive dysfunction (CD) is common among patients with the autoimmune disease systemic lupus erythematosus (SLE). Anti-ribosomal P autoantibodies associate with this dysfunction and have neuropathogenic effects that are mediated
Externí odkaz:
https://doaj.org/article/706d6d1a38ce4746a112602d79945e18
Publikováno v:
Antioxidants, Vol 12, Iss 2, p 403 (2023)
Traumatic brain injury (TBI) is brain damage due to external forces. Mild TBI (mTBI) is the most common form of TBI, and repeated mTBI is a risk factor for developing neurodegenerative diseases. Several mechanisms of neuronal damage have been describ
Externí odkaz:
https://doaj.org/article/b535e7ccff1e46bf82dba1a9f5d1f8a4
Publikováno v:
Frontiers in Physiology, Vol 12 (2021)
Traumatic brain injury (TBI) is a heterogeneous disorder that involves brain damage due to external forces. TBI is the main factor of death and morbidity in young males with a high incidence worldwide. TBI causes central nervous system (CNS) damage u
Externí odkaz:
https://doaj.org/article/d65866e582794617b278071ed981b654
Publikováno v:
Frontiers in Neuroscience, Vol 14 (2021)
Aging is an irreversible process and the primary risk factor for the development of neurodegenerative diseases, such as Alzheimer’s disease (AD). Mitochondrial impairment is a process that generates oxidative damage and ATP deficit; both factors ar
Externí odkaz:
https://doaj.org/article/77654832d3ca4a8797f7be87133bb7bb
Autor:
Rodrigo G. Mira, Matias Lira, Cheril Tapia-Rojas, Daniela L. Rebolledo, Rodrigo A. Quintanilla, Waldo Cerpa
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 13 (2020)
Problematic alcohol drinking and alcohol dependence are an increasing health problem worldwide. Alcohol abuse is responsible for approximately 5% of the total deaths in the world, but addictive consumption of it has a substantial impact on neurologic
Externí odkaz:
https://doaj.org/article/2b7f338a917f41059333618cc023d3f2
Publikováno v:
Redox Biology, Vol 18, Iss , Pp 279-294 (2018)
Tau is a key protein for microtubule stability; however, post-translationally modified tau contributes to neurodegenerative diseases by forming tau aggregates in the neurons. Previous reports from our group and others have shown that pathological for
Externí odkaz:
https://doaj.org/article/bf6e8f3c840e4b1b9356370f540c69fe