Zobrazeno 1 - 10
of 334
pro vyhledávání: '"Waldemar Priebe"'
Autor:
Maja Sołtyka-Krajewska, Marcin Ziemniak, Anna Zawadzka-Kazimierczuk, Paulina Skrzypczyk, Ewelina Siwiak-Niedbalska, Anna Jaśkiewicz, Rafał Zieliński, Izabela Fokt, Stanisław Skóra, Wiktor Koźmiński, Krzysztof Woźniak, Waldemar Priebe, Beata Pająk-Tarnacka
Publikováno v:
Biomedicines, Vol 12, Iss 10, p 2240 (2024)
Background: One defining feature of various aggressive cancers, including glioblastoma multiforme (GBM), is glycolysis upregulation, making its inhibition a promising therapeutic approach. One promising compound is 2-deoxy-d-glucose (2-DG), a d-gluco
Externí odkaz:
https://doaj.org/article/6d606b7bd79e4c7ba8de139e5102bb5f
Autor:
Grzegorz Świderski, Ewelina Gołębiewska, Natalia Kowalczyk, Monika Kalinowska, Renata Świsłocka, Elżbieta Wołejko, Urszula Wydro, Piotr Malinowski, Anna Pietryczuk, Adam Cudowski, Waldemar Priebe, Włodzimierz Lewandowski
Publikováno v:
Materials, Vol 17, Iss 6, p 1324 (2024)
This paper presents the results of a study of the effects of the lanthanide ions Ce3+, Pr3+, Nd3+ and Sm3+ on the electronic structure and antioxidant and biological (antimicrobial and cytotoxic) properties of p-coumaric acid (p-CAH2). Structural stu
Externí odkaz:
https://doaj.org/article/e299348a06ae4956a3a196ef0926ff91
Publikováno v:
Molecules, Vol 29, Iss 6, p 1298 (2024)
Glucose metabolism is a crucial biological pathway maintaining the activation of extra- and intracellular signaling pathways involved in the immune response. Immune cell stimulation via various environmental factors results in their activation and me
Externí odkaz:
https://doaj.org/article/5fe967be72f346ab92ef2441e07bc1fd
Autor:
John de Groot, Martina Ott, Jun Wei, Cynthia Kassab, Dexing Fang, Hinda Najem, Barbara O'Brien, Shiao-Pei Weathers, Carlos Kamiya Matsouka, Nazanin K Majd, Rebecca A Harrison, Gregory N Fuller, Jason T Huse, James P Long, Raymond Sawaya, Ganesh Rao, Tobey J MacDonald, Waldemar Priebe, Michael DeCuypere, Amy B Heimberger
Publikováno v:
CNS Oncology, Vol 11, Iss 02 (2022)
Aim: To ascertain the maximum tolerated dose (MTD)/maximum feasible dose (MFD) of WP1066 and p-STAT3 target engagement within recurrent glioblastoma (GBM) patients. Patients & methods: In a first-in-human open-label, single-center, single-arm 3 + 3 d
Externí odkaz:
https://doaj.org/article/f172809d74d443f2aaf6cc04d8836b6d
Autor:
J. Tyson McDonald, Francisco J. Enguita, Deanne Taylor, Robert J. Griffin, Waldemar Priebe, Mark R. Emmett, Mohammad M. Sajadi, Anthony D. Harris, Jean Clement, Joseph M. Dybas, Nukhet Aykin-Burns, Joseph W. Guarnieri, Larry N. Singh, Peter Grabham, Stephen B. Baylin, Aliza Yousey, Andrea N. Pearson, Peter M. Corry, Amanda Saravia-Butler, Thomas R. Aunins, Sadhana Sharma, Prashant Nagpal, Cem Meydan, Jonathan Foox, Christopher Mozsary, Bianca Cerqueira, Viktorija Zaksas, Urminder Singh, Eve Syrkin Wurtele, Sylvain V. Costes, Gustavo Gastão Davanzo, Diego Galeano, Alberto Paccanaro, Suzanne L. Meinig, Robert S. Hagan, Natalie M. Bowman, Matthew C. Wolfgang, Selin Altinok, Nicolae Sapoval, Todd J. Treangen, Pedro M. Moraes-Vieira, Charles Vanderburg, Douglas C. Wallace, Jonathan C. Schisler, Christopher E. Mason, Anushree Chatterjee, Robert Meller, Afshin Beheshti, Shannon M. Wallet, Robert Maile, Jason R. Mock, Jose L. Torres-Castillo, Miriya K. Love, Will Lovell, Colleen Rice, Olivia Mitchem, Dominique Burgess, Jessica Suggs, Jordan Jacobs
Publikováno v:
Cell Reports, Vol 37, Iss 3, Pp 109839- (2021)
Summary: MicroRNAs (miRNAs) are small non-coding RNAs involved in post-transcriptional gene regulation that have a major impact on many diseases and provide an exciting avenue toward antiviral therapeutics. From patient transcriptomic data, we determ
Externí odkaz:
https://doaj.org/article/86972322eb3c4fa78fa77d4ae3931268
Autor:
Beata Pająk, Rafał Zieliński, John Tyler Manning, Stanislava Matejin, Slobodan Paessler, Izabela Fokt, Mark R. Emmett, Waldemar Priebe
Publikováno v:
Molecules, Vol 27, Iss 18, p 5928 (2022)
Viral infection almost invariably causes metabolic changes in the infected cell and several types of host cells that respond to the infection. Among metabolic changes, the most prominent is the upregulated glycolysis process as the main pathway of gl
Externí odkaz:
https://doaj.org/article/7346b88f0edb46a68d2f99117b91573d
Autor:
Mayrim V. Rios Perez, David Roife, Bingbing Dai, Michael Pratt, Ryszard Dobrowolski, Ya'an Kang, Xinqun Li, Jithesh J. Augustine, Rafal Zielinski, Waldemar Priebe, Jason B. Fleming
Publikováno v:
Surgery Open Science, Vol 1, Iss 2, Pp 56-63 (2019)
Background: Auranofin, a Food and Drug Administration–approved anti-rheumatic agent with anticancer properties for lung and ovarian cancer, has never been studied for pancreatic cancer. We hypothesize that auranofin may prevent pancreatic ductal ad
Externí odkaz:
https://doaj.org/article/8c733fed64cf494fa7abb5b45dd29bc7
Autor:
Wolfram C.M. Dempke, Rafal Zielinski, Christina Winkler, Sandra Silberman, Susanne Reuther, Waldemar Priebe
Publikováno v:
European Journal of Cancer. 185:94-104
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5ae9d934b44be3899000b5e68e805090
https://doi.org/10.1016/j.ejca.2023.02.019
https://doi.org/10.1016/j.ejca.2023.02.019
Autor:
Moises Martinez-Castillo, Itzel Altamirano-Mendoza, Rafal Zielinski, Waldemar Priebe, Cristina Piña-Barba, Gabriela Gutierrez-Reyes
Publikováno v:
World Journal of Clinical Cases. 11:1224-1235
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aede62d0a3e8eac6461b3bac5c3eedd3
https://doi.org/10.12998/wjcc.v11.i6.1224
https://doi.org/10.12998/wjcc.v11.i6.1224
Autor:
Beata Pająk, Ewelina Siwiak-Niedbalska, Anna Jaśkiewicz, Maja Sołtyka, Rafał Zieliński, Tomasz Domoradzki, Izabela Fokt, Stanisław Skóra, Waldemar Priebe
Publikováno v:
Biomedicines, Vol 9, Iss 12, p 1749 (2021)
Over the last decade, we have seen tremendous progress in research on 2-deoxy-D-glucose (2-DG) and its analogs. Clinical trials of 2-DG have demonstrated the challenges of using 2-DG as a monotherapy, due to its poor drug-like characteristics, leadin
Externí odkaz:
https://doaj.org/article/0059a481e2a447b882323f913e1c01d8