Zobrazeno 1 - 10
of 219
pro vyhledávání: '"Waldemar, Wilczak"'
Autor:
Simon Kind, Carolina Palacios Castillo, Ria Schlichter, Natalia Gorbokon, Maximilian Lennartz, Lisa S. Hornsteiner, Sebastian Dwertmann Rico, Viktor Reiswich, Florian Viehweger, Martina Kluth, Claudia Hube-Magg, Christian Bernreuther, Franziska Büscheck, Till S. Clauditz, Christoph Fraune, Andrea Hinsch, Till Krech, Patrick Lebok, Stefan Steurer, Eike Burandt, Sarah Minner, Andreas H. Marx, Ronald Simon, Waldemar Wilczak, Guido Sauter, Anne Menz, Frank Jacobsen
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-17 (2024)
Abstract Background Kallikrein-related peptidase 7 (KLK7) is a chymotrypsin-like serine protease which is essential for the desquamation of corneocytes and thus plays a pivotal role in maintaining skin homeostasis. In cancer, KLK7 overexpression was
Externí odkaz:
https://doaj.org/article/5ac61efaf1d649688eb409482a34a7c5
Autor:
Viktor Reiswich, Natalia Gorbokon, Andreas M Luebke, Eike Burandt, Anne Menz, Martina Kluth, Claudia Hube‐Magg, Corinna Wittmer, Sören Weidemann, Christoph Fraune, Katharina Möller, Patrick Lebok, Guido Sauter, Ronald Simon, Ria Uhlig, Waldemar Wilczak, Frank Jacobsen, Sarah Minner, Rainer Krech, Christian Bernreuther, Andreas Marx, Stefan Steurer, Till Clauditz, Till Krech
Publikováno v:
The Journal of Pathology: Clinical Research, Vol 7, Iss 6, Pp 577-589 (2021)
Abstract Placental alkaline phosphatase (PLAP) is commonly expressed at high levels in testicular germ cell tumors. PLAP immunohistochemistry (IHC) is thus often used to confirm this diagnosis, especially in cases of putative metastasis. However, oth
Externí odkaz:
https://doaj.org/article/f8f371dd61e94921ac6133e6fda8a924
Autor:
Eike Burandt, Felix Lübbersmeyer, Natalia Gorbokon, Franziska Büscheck, Andreas M. Luebke, Anne Menz, Martina Kluth, Claudia Hube-Magg, Andrea Hinsch, Doris Höflmayer, Sören Weidemann, Christoph Fraune, Katharina Möller, Frank Jacobsen, Patrick Lebok, Till Sebastian Clauditz, Guido Sauter, Ronald Simon, Ria Uhlig, Waldemar Wilczak, Stefan Steurer, Sarah Minner, Rainer Krech, David Dum, Till Krech, Andreas Holger Marx, Christian Bernreuther
Publikováno v:
Biomarker Research, Vol 9, Iss 1, Pp 1-17 (2021)
Abstract Background The E-Cadherin gene (CDH1, Cadherin 1), located at 16q22.1 encodes for a calcium-dependent membranous glycoprotein with an important role in cellular adhesion and polarity maintenance. Methods To systematically determine E-Cadheri
Externí odkaz:
https://doaj.org/article/64455d5b74ec48b781f78e746707dc58
Autor:
Andreas Marx, Lena Koopmann, Doris Höflmayer, Franziska Büscheck, Claudia Hube-Magg, Stefan Steurer, Till Eichenauer, Till S. Clauditz, Waldemar Wilczak, Ronald Simon, Guido Sauter, Jakob R. Izbicki, Hartwig Huland, Hans Heinzer, Markus Graefen, Alexander Haese, Thorsten Schlomm, Christian Bernreuther, Patrick Lebok, Sarah Bonk
Publikováno v:
Cancer Biology & Medicine, Vol 18, Iss 1, Pp 245-255 (2021)
Objective: Anoctamin 7 (ANO7) is a calcium2+-dependent chloride ion channel protein. Its expression is restricted to prostate epithelial cells. The exact function is unknown. This study aimed to analyze ANO7 expression and its clinical significance i
Externí odkaz:
https://doaj.org/article/6e9b8f96c11a4874993b2ad9850c41ed
Autor:
Anne Menz, Timo Weitbrecht, Natalia Gorbokon, Franziska Büscheck, Andreas M. Luebke, Martina Kluth, Claudia Hube-Magg, Andrea Hinsch, Doris Höflmayer, Sören Weidemann, Christoph Fraune, Katharina Möller, Christian Bernreuther, Patrick Lebok, Till Clauditz, Guido Sauter, Ria Uhlig, Waldemar Wilczak, Stefan Steurer, Sarah Minner, Eike Burandt, Rainer Krech, David Dum, Till Krech, Andreas Marx, Ronald Simon
Publikováno v:
Molecular Medicine, Vol 27, Iss 1, Pp 1-16 (2021)
Abstract Background Cytokeratin 18 (CK18) is an intermediate filament protein of the cytokeratin acidic type I group and is primarily expressed in single-layered or “simple” epithelial tissues and carcinomas of different origin. Methods To system
Externí odkaz:
https://doaj.org/article/cf332205db044204aff909d26f58d346
Autor:
Stefan Steurer, Claudia Riemann, Franziska Büscheck, Andreas M. Luebke, Martina Kluth, Claudia Hube-Magg, Andrea Hinsch, Doris Höflmayer, Sören Weidemann, Christoph Fraune, Katharina Möller, Anne Menz, Margit Fisch, Michael Rink, Christian Bernreuther, Patrick Lebok, Till S. Clauditz, Guido Sauter, Ria Uhlig, Waldemar Wilczak, David Dum, Ronald Simon, Sarah Minner, Eike Burandt, Rainer Krech, Till Krech, Andreas H. Marx
Publikováno v:
Biomarker Research, Vol 9, Iss 1, Pp 1-14 (2021)
Abstract Background Tumor protein 63 (p63) is a transcription factor of the p53 gene family involved in differentiation of several tissues including squamous epithelium. p63 immunohistochemistry is broadly used for tumor classification but published
Externí odkaz:
https://doaj.org/article/18bcd142806b4cbfba926624af5c6c8c
Autor:
Noémi De Wispelaere, Sebastian Dwertmann Rico, Marcus Bauer, Andreas M Luebke, Martina Kluth, Franziska Büscheck, Claudia Hube-Magg, Doris Höflmayer, Natalia Gorbokon, Sören Weidemann, Katharina Möller, Christoph Fraune, Christian Bernreuther, Ronald Simon, Christian Kähler, Anne Menz, Andrea Hinsch, Frank Jacobsen, Patrick Lebok, Till Clauditz, Guido Sauter, Ria Uhlig, Waldemar Wilczak, Stefan Steurer, Eike Burandt, Rainer Krech, David Dum, Till Krech, Andreas Marx, Sarah Minner
Publikováno v:
PLoS ONE, Vol 17, Iss 7, p e0262877 (2022)
p16 (CDKN2A) is a member of the INK4 class of cell cycle inhibitors, which is often dysregulated in cancer. However, the prevalence of p16 expression in different cancer types is controversial. 15,783 samples from 124 different tumor types and 76 dif
Externí odkaz:
https://doaj.org/article/bf6a31afd44b49c5b13987bf53b48a20
Autor:
Till Eichenauer, Navid Shadanpour, Martina Kluth, Cosima Göbel, Sören Weidemann, Christoph Fraune, Franziska Büscheck, Claudia Hube-Magg, Christina Möller-Koop, Roland Dahlem, Margit Fisch, Michael Rink, Silke Riechardt, Eike Burandt, Christian Bernreuther, Sarah Minner, Ronald Simon, Guido Sauter, Waldemar Wilczak, Till Clauditz
Publikováno v:
World Journal of Surgical Oncology, Vol 18, Iss 1, Pp 1-9 (2020)
Abstract Background Deletions of 17p13 recurrently occur in renal cell carcinoma (RCC) but their prognostic role seems to be uncertain. Methods To determine prevalence, relationship with tumor phenotype, and patient prognosis, a tissue microarray con
Externí odkaz:
https://doaj.org/article/d8b18c157a1b41ca9f46842d6dcdd623
Autor:
Doris Höflmayer, Amélie Steinhoff, Claudia Hube‐Magg, Martina Kluth, Ronald Simon, Eike Burandt, Maria Christina Tsourlakis, Sarah Minner, Guido Sauter, Franziska Büscheck, Waldemar Wilczak, Stefan Steurer, Hartwig Huland, Markus Graefen, Alexander Haese, Hans Heinzer, Thorsten Schlomm, Frank Jacobsen, Andrea Hinsch, Alexandra M. Poos, Marcus Oswald, Karsten Rippe, Rainer König, Cornelia Schroeder
Publikováno v:
Molecular Oncology, Vol 14, Iss 1, Pp 129-138 (2020)
The chromatin‐organizing factor CCCTC‐binding factor (CTCF) is involved in transcriptional regulation, DNA‐loop formation, and telomere maintenance. To evaluate the clinical impact of CTCF in prostate cancer, we analyzed CTCF expression by immu
Externí odkaz:
https://doaj.org/article/9e4b25c2846d448eb86d06c8d43dcc1a
Autor:
Sebastian Dwertmann Rico MD, Moritz Mahnken MD, Franziska Büscheck MD, David Dum MD, Andreas M. Luebke MD, Martina Kluth PhD, Claudia Hube-Magg PhD, Andrea Hinsch MD, Doris Höflmayer MD, Christina Möller-Koop, Christoph Fraune MD, Katharina Möller MD, Anne Menz MD, Christian Bernreuther MD, Frank Jacobsen MD, Patrick Lebok MD, Till S. Clauditz MD, Guido Sauter MD, Ria Uhlig MD, Waldemar Wilczak MD, Ronald Simon PhD, Stefan Steurer MD, Sarah Minner MD, Eike Burandt MD, Till Krech MD, Andreas H. Marx MD
Publikováno v:
Technology in Cancer Research & Treatment, Vol 20 (2021)
Background: Mucin 5AC (MUC5AC) belongs to the glycoprotein family of secreted gel-forming mucins and is physiologically expressed in some epithelial cells. Studies have shown that MUC5AC is also expressed in several cancer types suggesting a potentia
Externí odkaz:
https://doaj.org/article/2c3def10c7fb40c8a93fd98baa91c5b6