Zobrazeno 1 - 10
of 202
pro vyhledávání: '"Waldemar, Debinski"'
Autor:
Josefa Karina Garcia Mora, John Robertson, Fang‐Chi Hsu, Richard Levon Shinn, Martha M. Larson, Christopher G. Rylander, Christopher T. Whitlow, Waldemar Debinski, Rafael V. Davalos, Gregory B.Daniel, John H. Rossmeisl
Publikováno v:
Journal of Veterinary Internal Medicine, Vol 36, Iss 3, Pp 1066-1074 (2022)
Abstract Background Brain tumor therapeutic responses can be quantified from magnetic resonance images (MRI) using 1‐ (1D) and 2‐dimensional (2D) linear and volumetric methods, but few studies in dogs compare these techniques. Hypotheses Linear m
Externí odkaz:
https://doaj.org/article/f4d652b4971a4d93886f9099f6e9b26f
Autor:
Teddy E. Kim, Shelby Puckett, Kailong Zhang, Denise M. Herpai, David A. Ornelles, John N. Davis, Anthony N. van den Pol, Waldemar Debinski, Douglas S. Lyles
Publikováno v:
Molecular Therapy: Oncolytics, Vol 22, Iss , Pp 232-244 (2021)
The difficulty of glioblastoma treatment makes it a good candidate for novel therapies, such as oncolytic viruses. Vesicular stomatitis virus expressing Lassa virus glycoprotein (Lassa-VSV) showed significant promise in animal models using establishe
Externí odkaz:
https://doaj.org/article/2b342b9766dc49d78a5a680f8de8cf26
Autor:
Brittanie Partridge, Allison Eardley, Brianna E. Morales, Sabrina N. Campelo, Melvin F. Lorenzo, Jason N. Mehta, Yukitaka Kani, Josefa K. Garcia Mora, Etse-Oghena Y. Campbell, Christopher B. Arena, Simon Platt, Akiva Mintz, Richard L. Shinn, Christopher G. Rylander, Waldemar Debinski, Rafael V. Davalos, John H. Rossmeisl
Publikováno v:
Frontiers in Veterinary Science, Vol 9 (2022)
The blood-brain barrier (BBB) presents a formidable obstacle to the effective delivery of systemically administered pharmacological agents to the brain, with ~5% of candidate drugs capable of effectively penetrating the BBB. A variety of biomaterials
Externí odkaz:
https://doaj.org/article/4dd41ae5e6864af2948892771284a5a7
Publikováno v:
Biomedicines, Vol 10, Iss 7, p 1598 (2022)
Glioblastoma (GBM) is the most commonly diagnosed and most lethal primary malignant brain tumor in adults. Standard treatments are ineffective, and despite promising results obtained in early phases of experimental clinical trials, the prognosis of G
Externí odkaz:
https://doaj.org/article/dd95c00a52794ebc900689c4c01186bf
Autor:
Stephanie Sanders, Denise M. Herpai, Analiz Rodriguez, Yue Huang, Jeff Chou, Fang-Chi Hsu, Darren Seals, Ryan Mott, Lance D. Miller, Waldemar Debinski
Publikováno v:
Cells, Vol 10, Iss 9, p 2485 (2021)
Glioblastoma (GBM) is the most aggressive malignant glioma. Therapeutic targeting of GBM is made more difficult due to its heterogeneity, resistance to treatment, and diffuse infiltration into the brain parenchyma. Better understanding of the tumor m
Externí odkaz:
https://doaj.org/article/e1ed0a887f3245439b1a6cad2f60d605
Autor:
Corbin A Helis, Shih-Ni Prim, Christina K Cramer, Roy Strowd, Glenn J Lesser, Jaclyn J White, Stephen B Tatter, Adrian W Laxton, Christopher Whitlow, Hui-Wen Lo, Waldemar Debinski, James D Ververs, Paul J Black, Michael D Chan
Publikováno v:
Neurooncol Pract
Background Re-irradiation for recurrent gliomas is a controversial treatment option with no clear standard dose or concurrent systemic therapy. Methods This series represents a single-institution retrospective review of patients treated with re-irrad
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25825fa319a9dcfe078a880265b5fb09
https://doi.org/10.1093/nop/npac032
https://doi.org/10.1093/nop/npac032
Autor:
Tadas K. Rimkus, Austin B. Arrigo, Dongqin Zhu, Richard L. Carpenter, Sherona Sirkisoon, Daniel Doheny, Angelina T. Regua, Grace L. Wong, Sara Manore, Calvin Wagner, Hui-Kuan Lin, Guangxu Jin, Jimmy Ruiz, Michael Chan, Waldemar Debinski, Hui-Wen Lo
Publikováno v:
Cancer Lett
Whether tumor suppressor candidate 2 (TUSC2) plays an important role in glioblastoma (GBM) progression is largely unknown. Whether TUSC2 undergoes polyubiquitination is unknown. Herein, we report that TUSC2 protein expression is reduced/lost in GBM c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::919d1602303d3b2100122e04793288c7
https://doi.org/10.1016/j.canlet.2022.01.029
https://doi.org/10.1016/j.canlet.2022.01.029
Autor:
George Kulik, Waldemar Debinski, Urs von Holzen, Ashok Hemal, Ralph D'Agostino, Young A. Choi, Yue Huang, Guangchao Sui, Sinan Zhu, Daniele Baiz, Yelena Karpova, Anabel Flores, Kyle C. Nelson, Ashok Pullikuth, Sazzad Hassan
There is accumulating evidence that continuous activation of the sympathetic nervous system due to psychosocial stress increases resistance to therapy and accelerates tumor growth via β2-adrenoreceptor signaling (ADRB2). However, the effector mechan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::80c5b6b33e58667e3d74e3ead11c999b
https://doi.org/10.1158/1541-7786.c.6541105
https://doi.org/10.1158/1541-7786.c.6541105
Autor:
Daniel R. Wahl, Roy E. Strowd, Theodore S. Lawrence, Corey Speers, Joel R. Eisner, Arul M. Chinnaiyan, Jann N. Sarkaria, Howard Colman, Daniel E. Spratt, Edwina Baskin-Bey, Sriram Venneti, Meredith A. Morgan, Alexander M. Hegedus, Waldemar Debinski, Tarik Bor, Carl Koschmann, Stefanie Stallard, Arvind Rao, Yangyang Yao, Weihua Zhou, Ayesha U. Kothari, Joseph Dresser, Kari Wilder-Romans, Hanshi Sun, Uchechi J. Nna, Christian K. Werner
Supplementary Figure S1: Additional expression data and comparisons of AR expression by subtype, age, sex, and common molecular alterations. Supplementary Figure S2. Tumor growth plots and mice weights for in vivo studies. Supplementary Figure S3: He
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33ad88dd4366195db01a6db15abda5b6
https://doi.org/10.1158/1535-7163.22521750
https://doi.org/10.1158/1535-7163.22521750
Autor:
Hui-Wen Lo, Waldemar Debinski, Kounosuke Watabe, Stephen B. Tatter, Glenn J. Lesser, Michael D. Chan, Boris C. Pasche, Dongqin Zhu, Sherona Sirkisoon, Richard L. Carpenter, Tadas K. Rimkus
This file contains supplemental materials and methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ac25f9412bc80c667f830023e288163
https://doi.org/10.1158/0008-5472.22419005
https://doi.org/10.1158/0008-5472.22419005