Zobrazeno 1 - 10
of 197
pro vyhledávání: '"Walburgis, Brenner"'
Autor:
Kathrin Stewen, Annika Droste, Christian Ruckes, Tania Elger, Susanne Theis, Anne-Sophie Heimes, Mona Wanda Schmidt, Lina Judit Schiestl, Philip Herbert Klecker, Katrin Almstedt, Marcus Schmidt, Walburgis Brenner, Annette Hasenburg, Roxana Schwab
Publikováno v:
Heliyon, Vol 10, Iss 15, Pp e35417- (2024)
Background: Modifiable lifestyle factors exert a substantial influence on the development of various diseases. The COVID-19 pandemic necessitated the implementation of containment measures to mitigate the viral spread, which affected the maintenance
Externí odkaz:
https://doaj.org/article/0314d6e361e94367923e2d2f24a6e487
Autor:
Christoph Hieber, Al-Hassan M. Mustafa, Sarah Neuroth, Sven Henninger, Hans-Peter Wollscheid, Joanna Zabkiewicz, Michelle Lazenby, Caroline Alvares, Siavosh Mahboobi, Falk Butter, Walburgis Brenner, Matthias Bros, Oliver H. Krämer
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 177, Iss , Pp 117076- (2024)
Hyperactive FMS-like receptor tyrosine kinase-3 mutants with internal tandem duplications (FLT3-ITD) are frequent driver mutations of aggressive acute myeloid leukemia (AML). Inhibitors of FLT3 produce promising results in rationally designed cotreat
Externí odkaz:
https://doaj.org/article/92a388417b2242c48063d7ece8629a1e
Autor:
Roxana Schwab, Lina Judit Schiestl, Lorena Cascant Ortolano, Philip Herbert Klecker, Mona Wanda Schmidt, Katrin Almstedt, Anne-Sophie Heimes, Walburgis Brenner, Kathrin Stewen, Marcus Schmidt, Annette Hasenburg
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
IntroductionVulvar cancer carries a favourable prognosis in early stages. However, therapeutic options for advanced or recurrent cases are limited despite a variety of therapeutic modalities, such as extensive surgical resection, chemotherapy, and ra
Externí odkaz:
https://doaj.org/article/54a202f43ba5407589087b76f8360978
Autor:
Ina Shehaj, Slavomir Krajnak, Katrin Almstedt, Yaman Degirmenci, Sophia Herzog, Antje Lebrecht, Valerie Catherine Linz, Roxana Schwab, Kathrin Stewen, Walburgis Brenner, Annette Hasenburg, Marcus Schmidt, Anne-Sophie Heimes
Publikováno v:
Biomedicines, Vol 12, Iss 6, p 1361 (2024)
Breast cancer (BC) poses a challenge in establishing new treatment strategies and identifying new prognostic and predictive markers due to the extensive genetic heterogeneity of BC. Very few studies have investigated the impact of mRNA expression of
Externí odkaz:
https://doaj.org/article/436bd216dafe4472bd66a3ed096dbda2
Autor:
Dennis Jung, Katrin Almstedt, Marco J. Battista, Alexander Seeger, Jörg Jäkel, Walburgis Brenner, Annette Hasenburg
Publikováno v:
Journal of Ovarian Research, Vol 16, Iss 1, Pp 1-11 (2023)
Abstract Background Granulosa cell tumors (GCT) are rare malignant ovarian tumors. The two subtypes, adult and juvenile granulosa cell tumors, differ in clinical and molecular characteristics. GCT are low-malignant tumors and are generally associated
Externí odkaz:
https://doaj.org/article/a20888a231e849a7bb1561c3e96ed1a5
Autor:
Slavomir Krajnak, Jannis Patrik Trier, Pauline Friederike Heinzmann, Katharina Anic, Anne-Sophie Heimes, Amelie Loewe, Marcus Schmidt, Marco Johannes Battista, Annette Hasenburg, Walburgis Brenner
Publikováno v:
EXCLI Journal : Experimental and Clinical Sciences, Vol 22, Pp 114-130 (2023)
In metastatic breast cancer (MBC), PIK3CA mutations, activating the phosphatidylinositol 3-kinase (PI3K) signaling pathway seem to be associated with chemotherapy resistance and poor outcome. Inhibition of the PI3K signaling pathway may lead to sensi
Externí odkaz:
https://doaj.org/article/f53593c33c4d41c089131f2ffb937c14
Autor:
Magdalena Keller, Katharina Rohlf, Annika Glotzbach, Gregor Leonhardt, Simon Lüke, Katharina Derksen, Özlem Demirci, Defne Göçener, Mohammad AlWahsh, Jörg Lambert, Cecilia Lindskog, Marcus Schmidt, Walburgis Brenner, Matthias Baumann, Eldar Zent, Mia-Lisa Zischinsky, Birte Hellwig, Katrin Madjar, Jörg Rahnenführer, Nina Overbeck, Jörg Reinders, Cristina Cadenas, Jan G. Hengstler, Karolina Edlund, Rosemarie Marchan
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 42, Iss 1, Pp 1-18 (2023)
Abstract Background Intrinsic or acquired resistance to HER2-targeted therapy is often a problem when small molecule tyrosine kinase inhibitors or antibodies are used to treat patients with HER2 positive breast cancer. Therefore, the identification o
Externí odkaz:
https://doaj.org/article/3ce2fcec0f4f49f29458097699d65efb
Autor:
Mona Wanda Schmidt, Walburgis Brenner, Susanne Gebhard, Marcus Schmidt, Susanne Singer, Lina Weidenbach, Harriett Hahn, Diana Puzankova, Bettina Blau-Schneider, Antje Lehnert, Marco Johannes Battista, Katrin Almstedt, Anja Lütkemeyer, Markus Philipp Radsak, Aline Mähringer-Kunz, Slavomir Krajnak, Valerie Cathrine Linz, Roxana Schwab, Boris Gabriel, Annette Hasenburg, Katharina Anic
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
Fatigue is a very common side effect during intravenous chemotherapy. Unfortunately, only few effective therapeutic options are available, mostly based on daily activity. In our pilot trial we were able to demonstrate that intermittent fasting can re
Externí odkaz:
https://doaj.org/article/6474b128f3b1416b8f4dbe20fd706650
Autor:
Stefanie Zschäbitz, Marie Mikuteit, Christine Stöhr, Edwin Herrmann, Iris Polifka, Abbas Agaimy, Lutz Trojan, Philipp Ströbel, Frank Becker, Christian Wülfing, Peter Barth, Michael Stöckle, Michael Staehler, Christian Stief, Axel Haferkamp, Markus Hohenfellner, Stefan Duensing, Stephan Macher-Göppinger, Bernd Wullich, Joachim Noldus, Walburgis Brenner, Frederik C. Roos, Bernhard Walter, Wolfgang Otto, Maximilian Burger, Andres Jan Schrader, Arndt Hartmann, Franziska Erlmeier, Sandra Steffens
Publikováno v:
Discover Oncology, Vol 13, Iss 1, Pp 1-12 (2022)
Abstract Background Nectin-4 contributes to tumor proliferation, lymphangiogenesis and angiogenesis in malignant tumors and is an emerging target in tumor therapy. In renal cell carcinoma (RCC) VEGF-directed tyrosine kinase inhibitors and checkpoint
Externí odkaz:
https://doaj.org/article/f48c4647fe714704ac7639eb9dc60db9
Autor:
Anne-Sophie Heimes, Natali Riedel, Katrin Almstedt, Slavomir Krajnak, Roxana Schwab, Kathrin Stewen, Antje Lebrecht, Marco Johannes Battista, Walburgis Brenner, Annette Hasenburg, Marcus Schmidt
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 20, p 15219 (2023)
Due to a higher mutational load, triple-negative breast cancer (TNBC) is characterized by a higher immunogenicity compared to other subtypes. In this context, we analyzed the prognostic significance of tumor-infiltrating plasma cells in a cohort of 1
Externí odkaz:
https://doaj.org/article/a6f440fbcf06470bbc5e1e98fdcecde8