Telomere aberrations, including telomere loss, doublets, and extreme shortening, are increased in patients with infertility

Autor: Catherine Yardin, Anne-Claude Tabet, Michael Fenech, Wala Najar, Georges Deschenes, Claire Borie, Marguerite Miguet, Alain Dieterlen, Noufissa Oudrhiri, Radhia M'kacher, Valentine Marquet, Michael Grynberg, Leonhard Heidingsfelder, Nadège Wilhelm-Murer, Annelise Bennaceur-Griscelli, Steffen Junker, Bruno Colicchio, Philippe Voisin, Patrice Carde, William M. Hempel, Mustafa Al Jawhari, Eric Jeandidier

Publikováno v: M'kacher, R, Colicchio, B, Marquet, V, Borie, C, Najar, W, Hempel, W M, Heidingsfelder, L, Oudrhiri, N, Al Jawhari, M, Wilhelm-Murer, N, Miguet, M, Dieterlen, A, Deschênes, G, Tabet, A-C, Junker, S, Grynberg, M, Fenech, M, Bennaceur-Griscelli, A, Voisin, P, Carde, P, Jeandidier, E & Yardin, C 2021, ' Telomere aberrations, including telomere loss, doublets, and extreme shortening, are increased in patients with infertility ', Fertility and Sterility, vol. 115, no. 1, pp. 164-173 . https://doi.org/10.1016/j.fertnstert.2020.07.005

OBJECTIVE: To test the hypothesis that telomere shortening and/or loss are risk factors for infertility.DESIGN: Retrospective analysis of the telomere status in patients with infertility using conventional cytogenetic data collected prospectively.SET

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::508e0d99b33b91e05002b4e393d26d11
https://doi.org/10.1016/j.fertnstert.2020.07.005

Telomere and Centromere Staining Followed by M-FISH Improves Diagnosis of Chromosomal Instability and Its Clinical Utility

Autor: Wendy Kerbrat, Annelise Bennaceur-Griscelli, Philippe Voisin, Kevin Soehnlen, Wala Najar, Valentine Marquet, Marguerite Miguet, Andreas Plesch, Claire Borie, William M. Hempel, Nadège Wilhelm-Murer, Catherine Yardin, Anne-Claude Tabet, Noufissa Oudrhiri, Georges Deschenes, Michael Fenech, Bruno Colicchio, Micheline Fontaine Arnoux, Eric Jeandidier, Radhia M'kacher, Catherine Ferrapie, Alain Dieterlen, Theodore Girinsky, Leonhard Heidingsfelder, Patrice Carde, Steffen Junker

Publikováno v: Genes
Volume 11
Issue 5
M’kacher, R, Colicchio, B, Borie, C, Junker, S, Marquet, V, Heidingsfelder, L, Soehnlen, K, Najar, W, Hempel, W M, Oudrhiri, N, Wilhelm-Murer, N, Miguet, M, Arnoux, M, Ferrapie, C, Kerbrat, W, Plesch, A, Dieterlen, A, Girinsky, T, Voisin, P, Deschenes, G, Tabet, A C, Yardin, C, Bennaceur-Griscelli, A, Fenech, M, Carde, P & Jeandidier, E 2020, ' Telomere and centromere staining followed by m-fish improves diagnosis of chromosomal instability and its clinical utility ', Genes, vol. 11, no. 5, 475 . https://doi.org/10.3390/genes11050475
Genes, Vol 11, Iss 475, p 475 (2020)

Dicentric chromosomes are a relevant marker of chromosomal instability. Their appearance is associated with telomere dysfunction, leading to cancer progression and a poor clinical outcome. Here, we present Telomere and Centromere staining followed by

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e01b6535156e46bc1fa6cc62b2d0903