Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Wala JA"'
Autor:
Andrea Sarasola-Sanz, Andreas M. Ray, Ainhoa Insausti-Delgado, Nerea Irastorza-Landa, Wala Jaser Mahmoud, Doris Brötz, Carlos Bibián-Nogueras, Florian Helmhold, Christoph Zrenner, Ulf Ziemann, Eduardo López-Larraz, Ander Ramos-Murguialday
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 12 (2024)
Introduction: The primary constraint of non-invasive brain-machine interfaces (BMIs) in stroke rehabilitation lies in the poor spatial resolution of motor intention related neural activity capture. To address this limitation, hybrid brain-muscle-mach
Externí odkaz:
https://doaj.org/article/7becc8bab7d64b9f98c4e5d0e9ac2e16
Autor:
Wala JA; Dana-Farber Cancer Institute, 450 Brookline Avenue, Dana Building 2nd Floor, Room 2-140, Boston, MA 02215, USA., Hanna GJ; Dana-Farber Cancer Institute, 450 Brookline Avenue, Dana Building 2nd Floor, Room 2-140, Boston, MA 02215, USA. Electronic address: glenn_hanna@dfci.harvard.edu.
Publikováno v:
Hematology/oncology clinics of North America [Hematol Oncol Clin North Am] 2023 Dec; Vol. 37 (6), pp. 1149-1168. Date of Electronic Publication: 2023 Jun 21.
Autor:
Rodriguez-Martin B; Department of Zoology, Genetics and Physical Anthropology, Universidade de Santiago de Compostela, Santiago de Compostela, Spain.; Biomedical Research Centre (CINBIO), University of Vigo, Vigo, Spain.; Centre for Research in Molecular Medicine and Chronic Diseases (CIMUS), Universidade de Santiago de Compostela, Santiago de Compostela, Spain., Alvarez EG; Department of Zoology, Genetics and Physical Anthropology, Universidade de Santiago de Compostela, Santiago de Compostela, Spain.; Biomedical Research Centre (CINBIO), University of Vigo, Vigo, Spain.; Centre for Research in Molecular Medicine and Chronic Diseases (CIMUS), Universidade de Santiago de Compostela, Santiago de Compostela, Spain., Baez-Ortega A; Transmissible Cancer Group, Department of Veterinary Medicine, University of Cambridge, Cambridge, UK., Zamora J; Department of Zoology, Genetics and Physical Anthropology, Universidade de Santiago de Compostela, Santiago de Compostela, Spain.; Centre for Research in Molecular Medicine and Chronic Diseases (CIMUS), Universidade de Santiago de Compostela, Santiago de Compostela, Spain.; The Biomedical Research Centre (CINBIO), Universidade de Vigo, Vigo, Spain.; Wellcome Sanger Institute, Wellcome Genome Campus, Cambridge, UK., Supek F; Genome Data Science, Institute for Research in Biomedicine (IRB Barcelona), The Barcelona Institute of Science and Technology (BIST), Barcelona, Spain.; Institucio Catalana de Recerca i Estudis Avançats (ICREA), Barcelona, Spain., Demeulemeester J; The Francis Crick Institute, London, UK.; Department of Human Genetics, University of Leuven, Leuven, Belgium., Santamarina M; Department of Zoology, Genetics and Physical Anthropology, Universidade de Santiago de Compostela, Santiago de Compostela, Spain.; Biomedical Research Centre (CINBIO), University of Vigo, Vigo, Spain.; Genomes and Disease, Centre for Research in Molecular Medicine and Chronic Diseases (CIMUS), Universidade de Santiago de Compostela, Santiago de Compostela, Spain., Ju YS; Graduate School of Medical Science and Engineering, Korea Advanced Institute of Science and Technology, Daejeon, South Korea.; Cancer Ageing and Somatic Mutation Programme, Wellcome Sanger Institute, Cambridge, UK., Temes J; Department of Zoology, Genetics and Physical Anthropology, Universidade de Santiago de Compostela, Santiago de Compostela, Spain.; Centre for Research in Molecular Medicine and Chronic Diseases (CIMUS), Universidade de Santiago de Compostela, Santiago de Compostela, Spain., Garcia-Souto D; Genomes and Disease, Centre for Research in Molecular Medicine and Chronic Diseases (CIMUS), Universidade de Santiago de Compostela, Santiago de Compostela, Spain., Detering H; Biomedical Research Centre (CINBIO), University of Vigo, Vigo, Spain.; Department of Biochemistry, Genetics and Immunology, University of Vigo, Vigo, Spain.; Galicia Sur Health Research Institute, Vigo, Spain., Li Y; Wellcome Sanger Institute, Wellcome Genome Campus, Cambridge, UK., Rodriguez-Castro J; Genomes and Disease, Centre for Research in Molecular Medicine and Chronic Diseases (CIMUS), Universidade de Santiago de Compostela, Santiago de Compostela, Spain., Dueso-Barroso A; Faculty of Science and Technology, University of Vic-Central University of Catalonia (UVic-UCC), Vic, Spain.; Barcelona Supercomputing Center (BSC), Barcelona, Spain., Bruzos AL; Department of Zoology, Genetics and Physical Anthropology, Universidade de Santiago de Compostela, Santiago de Compostela, Spain.; Biomedical Research Centre (CINBIO), University of Vigo, Vigo, Spain.; Genomes and Disease, Centre for Research in Molecular Medicine and Chronic Diseases (CIMUS), Universidade de Santiago de Compostela, Santiago de Compostela, Spain., Dentro SC; The Francis Crick Institute, London, UK.; Experimental Cancer Genetics, Wellcome Sanger Institute, Cambridge, UK.; Oxford Big Data Institute, University of Oxford, Oxford, UK., Blanco MG; DNA Repair and Genome Integrity, Centre for Research in Molecular Medicine and Chronic Diseases (CIMUS), Universidade de Santiago de Compostela, Santiago de Compostela, Spain.; Department of Biochemistry and Molecular Biology, Universidade de Santiago de Compostela, Santiago de Compostela, Spain., Contino G; Medical Research Council (MRC) Cancer Unit, University of Cambridge, Cambridge, UK., Ardeljan D; Department of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, Baltimore, MD, USA., Tojo M; The Biomedical Research Centre (CINBIO), Universidade de Vigo, Vigo, Spain.; Department of Biochemistry, Genetics and Immunology, University of Vigo, Vigo, Spain., Roberts ND; Wellcome Sanger Institute, Wellcome Genome Campus, Cambridge, UK., Zumalave S; Department of Zoology, Genetics and Physical Anthropology, Universidade de Santiago de Compostela, Santiago de Compostela, Spain.; Genomes and Disease, Centre for Research in Molecular Medicine and Chronic Diseases (CIMUS), Universidade de Santiago de Compostela, Santiago de Compostela, Spain., Edwards PA; University of Cambridge, Cambridge, UK.; Li Ka Shing Centre, Cancer Research UK Cambridge Institute, University of Cambridge, Cambridge, UK., Weischenfeldt J; European Molecular Biology Laboratory (EMBL), Genome Biology Unit, Heidelberg, Germany.; Finsen Laboratory and Biotech Research & Innovation Centre (BRIC), University of Copenhagen, Copenhagen, Denmark.; Department of Urology, Charité Universitätsmedizin Berlin, Berlin, Germany., Puiggròs M; Barcelona Supercomputing Center (BSC), Barcelona, Spain., Chong Z; Department of Bioinformatics and Computational Biology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.; Department of Genetics and Informatics Institute, University of Alabama at Birmingham (UAB) School of Medicine, Birmingham, AL, USA., Chen K; University of Texas MD Anderson Cancer Center, Houston, TX, USA., Lee EA; Division of Genetics and Genomics, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA., Wala JA; The Broad Institute of Harvard and MIT, Cambridge, MA, USA.; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA.; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.; Harvard Medical School, Boston, MA, USA., Raine KM; Cancer Ageing and Somatic Mutation Programme, Wellcome Sanger Institute, Cambridge, UK., Butler A; Cancer Ageing and Somatic Mutation Programme, Wellcome Sanger Institute, Cambridge, UK., Waszak SM; European Molecular Biology Laboratory (EMBL), Genome Biology Unit, Heidelberg, Germany., Navarro FCP; Program in Computational Biology and Bioinformatics, Yale University, New Haven, CT, USA.; Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT, USA.; Department of Computer Science, Yale University, New Haven, CT, USA., Schumacher SE; The Broad Institute of Harvard and MIT, Cambridge, MA, USA.; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA.; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA., Monlong J; Department of Human Genetics, McGill University, Montreal, Québec, Canada., Maura F; Cancer Ageing and Somatic Mutation Programme, Wellcome Sanger Institute, Cambridge, UK.; Department of Oncology and Onco-Hematology, University of Milan, Milan, Italy.; Department of Medical Oncology and Hematology, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy., Bolli N; Department of Oncology and Onco-Hematology, University of Milan, Milan, Italy.; Department of Medical Oncology and Hematology, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy., Bourque G; Canadian Center for Computational Genomics, McGill University, Montreal, Quebec, Canada., Gerstein M; Program in Computational Biology and Bioinformatics, Yale University, New Haven, CT, USA.; Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT, USA.; Department of Computer Science, Yale University, New Haven, CT, USA., Park PJ; Department of Biomedical Informatics, Harvard Medical School, Boston, MA, USA.; Ludwig Center at Harvard, Boston, MA, USA., Wedge DC; Cancer Ageing and Somatic Mutation Programme, Wellcome Sanger Institute, Cambridge, UK.; Experimental Cancer Genetics, Wellcome Sanger Institute, Cambridge, UK.; Oxford NIHR Biomedical Research Centre, Oxford, UK., Beroukhim R; The Broad Institute of Harvard and MIT, Cambridge, MA, USA.; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.; Harvard Medical School, Boston, MA, USA., Torrents D; Institucio Catalana de Recerca i Estudis Avançats (ICREA), Barcelona, Spain.; Barcelona Supercomputing Center (BSC), Barcelona, Spain., Korbel JO; European Molecular Biology Laboratory (EMBL), Genome Biology Unit, Heidelberg, Germany.; European Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI), Cambridge, UK., Martincorena I; Wellcome Sanger Institute, Wellcome Genome Campus, Cambridge, UK., Fitzgerald RC; Medical Research Council (MRC) Cancer Unit, University of Cambridge, Cambridge, UK., Van Loo P; The Francis Crick Institute, London, UK.; Department of Human Genetics, University of Leuven, Leuven, Belgium., Kazazian HH; Department of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, Baltimore, MD, USA., Burns KH; Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, Baltimore, MD, USA.; McKusick-Nathans Institute of Genetic Medicine, Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins University School of Medicine, Baltimore, MD, USA., Campbell PJ; Wellcome Sanger Institute, Wellcome Genome Campus, Cambridge, UK. pc8@sanger.ac.uk.; Department of Haematology, University of Cambridge, Cambridge, UK. pc8@sanger.ac.uk., Tubio JMC; Department of Zoology, Genetics and Physical Anthropology, Universidade de Santiago de Compostela, Santiago de Compostela, Spain. jose.mc.tubio@usc.es.; Biomedical Research Centre (CINBIO), University of Vigo, Vigo, Spain. jose.mc.tubio@usc.es.; Centre for Research in Molecular Medicine and Chronic Diseases (CIMUS), Universidade de Santiago de Compostela, Santiago de Compostela, Spain. jose.mc.tubio@usc.es.; Cancer Ageing and Somatic Mutation Programme, Wellcome Sanger Institute, Cambridge, UK. jose.mc.tubio@usc.es.
Publikováno v:
Nature genetics [Nat Genet] 2023 Jun; Vol. 55 (6), pp. 1080.
Autor:
Rheinbay E; The Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Center for Cancer Research, Massachusetts General Hospital, Charlestown, MA, USA.; Harvard Medical School, Boston, MA, USA., Nielsen MM; Department of Molecular Medicine (MOMA), Aarhus University Hospital, Aarhus, Denmark., Abascal F; Wellcome Trust Sanger Institute, Hinxton, UK., Wala JA; The Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Bioinformatics and Integrative Genomics, Harvard University, Cambridge, MA, USA., Shapira O; The Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA., Tiao G; The Broad Institute of MIT and Harvard, Cambridge, MA, USA., Hornshøj H; Department of Molecular Medicine (MOMA), Aarhus University Hospital, Aarhus, Denmark., Hess JM; The Broad Institute of MIT and Harvard, Cambridge, MA, USA., Juul RI; Department of Molecular Medicine (MOMA), Aarhus University Hospital, Aarhus, Denmark., Lin Z; The Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Harvard University, Cambridge, MA, USA., Feuerbach L; Division of Applied Bioinformatics, German Cancer Research Center (DKFZ), Heidelberg, Germany., Sabarinathan R; Institute for Research in Biomedicine (IRB Barcelona), The Barcelona Institute of Science and Technology, Barcelona, Spain.; Research Program on Biomedical Informatics, Universitat Pompeu Fabra, Barcelona, Spain., Madsen T; Department of Molecular Medicine (MOMA), Aarhus University Hospital, Aarhus, Denmark., Kim J; The Broad Institute of MIT and Harvard, Cambridge, MA, USA., Mularoni L; Institute for Research in Biomedicine (IRB Barcelona), The Barcelona Institute of Science and Technology, Barcelona, Spain.; Research Program on Biomedical Informatics, Universitat Pompeu Fabra, Barcelona, Spain., Shuai S; Computational Biology Program, Ontario Institute for Cancer Research, Toronto, Ontario, Canada.; Ontario Institute for Cancer Research, Toronto, Ontario, Canada., Lanzós A; Department for BioMedical Research, University of Bern, Bern, Switzerland.; Graduate School of Cellular and Biomedical Sciences, University of Bern, Bern, Switzerland.; Department of Medical Oncology, Bern University Hospital, University of Bern, Bern, Switzerland., Herrmann C; Division of Theoretical Bioinformatics, German Cancer Research Center (DKFZ), Heidelberg, Germany.; Bioquant Center, Institute of Pharmacy and Molecular Biotechnology, University of Heidelberg, Heidelberg, Germany., Maruvka YE; The Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Center for Cancer Research, Massachusetts General Hospital, Charlestown, MA, USA., Shen C; Department of Cell Biology, Harvard Medical School, Boston, MA, USA.; cBio Center, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA., Amin SB; Department of Genomic Medicine, University of Texas MD Anderson Cancer Center, Houston, TX, USA.; Graduate Program in Structural and Computational Biology and Molecular Biophysics, Baylor College of Medicine, Houston, TX, USA., Bandopadhayay P; The Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA., Bertl J; Department of Molecular Medicine (MOMA), Aarhus University Hospital, Aarhus, Denmark., Boroevich KA; Laboratory for Medical Science Mathematics, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan., Busanovich J; The Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA., Carlevaro-Fita J; Department for BioMedical Research, University of Bern, Bern, Switzerland.; Graduate School of Cellular and Biomedical Sciences, University of Bern, Bern, Switzerland.; Department of Medical Oncology, Bern University Hospital, University of Bern, Bern, Switzerland., Chakravarty D; Department of Genitourinary Medical Oncology - Research, Division of Cancer Medicine, University of Texas MD Anderson Cancer Center, Houston, TX, USA.; Department of Urology, Icahn school of Medicine at Mount Sinai, New York, NY, USA., Chan CWY; Division of Theoretical Bioinformatics, German Cancer Research Center (DKFZ), Heidelberg, Germany.; Faculty of Biosciences, Heidelberg University, Heidelberg, Germany., Craft D; Department of Radiation Oncology, Harvard Medical School, Massachusetts General Hospital, Boston, MA, USA., Dhingra P; Department of Physiology and Biophysics, Weill Cornell Medicine, New York, NY, USA.; Institute for Computational Biomedicine, Weill Cornell Medicine, New York, NY, USA., Diamanti K; Science for Life Laboratory, Department of Cell and Molecular Biology, Uppsala University, Uppsala, Sweden., Fonseca NA; European Bioinformatics Institute, European Molecular Biology Laboratory, Hinxton, UK., Gonzalez-Perez A; Institute for Research in Biomedicine (IRB Barcelona), The Barcelona Institute of Science and Technology, Barcelona, Spain.; Research Program on Biomedical Informatics, Universitat Pompeu Fabra, Barcelona, Spain., Guo Q; Bioinformatics Research Centre (BiRC), Aarhus University, Aarhus, Denmark., Hamilton MP; Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX, USA., Haradhvala NJ; The Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Center for Cancer Research, Massachusetts General Hospital, Charlestown, MA, USA., Hong C; Division of Applied Bioinformatics, German Cancer Research Center (DKFZ), Heidelberg, Germany.; Faculty of Biosciences, Heidelberg University, Heidelberg, Germany., Isaev K; Computational Biology Program, Ontario Institute for Cancer Research, Toronto, Ontario, Canada.; Department of Medical Biophysics, University of Toronto, Toronto, Ontario, Canada., Johnson TA; Laboratory for Medical Science Mathematics, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan., Juul M; Department of Molecular Medicine (MOMA), Aarhus University Hospital, Aarhus, Denmark., Kahles A; Division of Computational Biology, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Kahraman A; Institute of Molecular Life Sciences and Swiss Institute of Bioinformatics, University of Zurich, Zurich, Switzerland., Kim Y; Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea., Komorowski J; Science for Life Laboratory, Department of Cell and Molecular Biology, Uppsala University, Uppsala, Sweden.; Institute of Computer Science, Polish Academy of Sciences, Warsaw, Poland., Kumar K; The Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA., Kumar S; Program in Computational Biology and Bioinformatics, Yale University, New Haven, CT, USA., Lee D; Program in Computational Biology and Bioinformatics, Yale University, New Haven, CT, USA., Lehmann KV; Division of Computational Biology, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Li Y; SBGD Inc, Cambridge, MA, USA.; Department of Haematology, University of Cambridge, Cambridge, UK., Liu EM; Department of Physiology and Biophysics, Weill Cornell Medicine, New York, NY, USA.; Institute for Computational Biomedicine, Weill Cornell Medicine, New York, NY, USA., Lochovsky L; Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT, USA., Park K; Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea., Pich O; Institute for Research in Biomedicine (IRB Barcelona), The Barcelona Institute of Science and Technology, Barcelona, Spain.; Research Program on Biomedical Informatics, Universitat Pompeu Fabra, Barcelona, Spain., Roberts ND; Department of Haematology, University of Cambridge, Cambridge, UK., Saksena G; The Broad Institute of MIT and Harvard, Cambridge, MA, USA., Schumacher SE; The Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA., Sidiropoulos N; Biotech Research & Innovation Centre (BRIC), The Finsen Laboratory, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark., Sieverling L; Division of Applied Bioinformatics, German Cancer Research Center (DKFZ), Heidelberg, Germany.; Faculty of Biosciences, Heidelberg University, Heidelberg, Germany., Sinnott-Armstrong N; Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA., Stewart C; The Broad Institute of MIT and Harvard, Cambridge, MA, USA., Tamborero D; Institute for Research in Biomedicine (IRB Barcelona), The Barcelona Institute of Science and Technology, Barcelona, Spain.; Research Program on Biomedical Informatics, Universitat Pompeu Fabra, Barcelona, Spain., Tubio JMC; Department of Zoology, Genetics and Physical Anthropology, Universidade de Santiago de Compostela, Santiago de Compostela, Spain.; Centre for Research in Molecular Medicine and Chronic Diseases (CIMUS), Universidade de Santiago de Compostela, Santiago de Compostela, Spain.; The Biomedical Research Centre (CINBIO), Universidade de Vigo, Vigo, Spain., Umer HM; Science for Life Laboratory, Department of Cell and Molecular Biology, Uppsala University, Uppsala, Sweden.; Department of Oncology-Pathology, Science for Life Laboratory, Karolinska Institute, Stockholm, Sweden., Uusküla-Reimand L; Genetics and Genome Biology Program, SickKids Research Institute, Toronto, Ontario, Canada.; Department of Gene Technology, Tallinn University of Technology, Tallinn, Estonia., Wadelius C; Science for Life Laboratory, Department of Immunology, Genetics and Pathology, Uppsala University, Uppsala, Sweden., Wadi L; Computational Biology Program, Ontario Institute for Cancer Research, Toronto, Ontario, Canada., Yao X; New York Genome Center, New York, NY, USA., Zhang CZ; Department of Biostatistics and Computational Biology, Dana-Farber Cancer Institute, Boston, MA, USA.; Department of Biomedical Informatics, Harvard Medical School, Boston, MA, USA., Zhang J; Program in Computational Biology and Bioinformatics, Yale University, New Haven, CT, USA., Haber JE; Department of Biology and Rosenstiel Basic Medical Sciences Research Center, Brandeis University, Waltham, MA, USA., Hobolth A; Bioinformatics Research Centre (BiRC), Aarhus University, Aarhus, Denmark., Imielinski M; New York Genome Center, New York, NY, USA.; Department of Pathology and Laboratory Medicine, and Englander Institute for Precision Medicine, and Institute for Computational Biomedicine, and Meyer Cancer Center, Weill Cornell Medicine, New York, NY, USA., Kellis M; The Broad Institute of MIT and Harvard, Cambridge, MA, USA.; MIT Computer Science and Artificial Intelligence Laboratory, Cambridge, MA, USA., Lawrence MS; The Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Center for Cancer Research, Massachusetts General Hospital, Charlestown, MA, USA., von Mering C; Institute of Molecular Life Sciences and Swiss Institute of Bioinformatics, University of Zurich, Zurich, Switzerland., Nakagawa H; Laboratory for Cancer Genomics, RIKEN Center for Integrative Medical Sciences, Tokyo, Japan., Raphael BJ; Department of Computer Science, Princeton University, Princeton, NJ, USA., Rubin MA; Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, NY, USA.; Englander Institute for Precision Medicine, Weill Cornell Medicine, New York, NY, USA.; Meyer Cancer Center, Weill Cornell Medicine, New York, NY, USA., Sander C; Department of Cell Biology, Harvard Medical School, Boston, MA, USA.; cBio Center, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA., Stein LD; Computational Biology Program, Ontario Institute for Cancer Research, Toronto, Ontario, Canada.; Ontario Institute for Cancer Research, Toronto, Ontario, Canada., Stuart JM; Center for Biomolecular Science and Engineering, University of California at Santa Cruz, Santa Cruz, CA, USA., Tsunoda T; Laboratory for Medical Science Mathematics, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan.; Department of Medical Science Mathematics, Medical Research Institute, Tokyo Medical and Dental University, Tokyo, Japan.; Laboratory for Medical Science Mathematics, Department of Biological Sciences, Graduate School of Science, The University of Tokyo, Tokyo, Japan., Wheeler DA; Human Genome Sequencing Center, Baylor College of Medicine, Houston, TX, USA., Johnson R; Department for BioMedical Research, University of Bern, Bern, Switzerland.; Department of Medical Oncology, Bern University Hospital, University of Bern, Bern, Switzerland., Reimand J; Computational Biology Program, Ontario Institute for Cancer Research, Toronto, Ontario, Canada.; Department of Medical Biophysics, University of Toronto, Toronto, Ontario, Canada., Gerstein M; Program in Computational Biology and Bioinformatics, Yale University, New Haven, CT, USA.; Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT, USA.; Department of Computer Science, Yale University, New Haven, CT, USA., Khurana E; Department of Physiology and Biophysics, Weill Cornell Medicine, New York, NY, USA.; Institute for Computational Biomedicine, Weill Cornell Medicine, New York, NY, USA.; Englander Institute for Precision Medicine, Weill Cornell Medicine, New York, NY, USA.; Meyer Cancer Center, Weill Cornell Medicine, New York, NY, USA., Campbell PJ; Wellcome Trust Sanger Institute, Hinxton, UK.; Department of Haematology, University of Cambridge, Cambridge, UK., López-Bigas N; Institute for Research in Biomedicine (IRB Barcelona), The Barcelona Institute of Science and Technology, Barcelona, Spain.; Research Program on Biomedical Informatics, Universitat Pompeu Fabra, Barcelona, Spain.; Catalan Institution for Research and Advanced Studies (ICREA), Barcelona, Spain., Weischenfeldt J; Biotech Research & Innovation Centre (BRIC), The Finsen Laboratory, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark. joachim.weischenfeldt@bric.ku.dk.; Genome Biology Unit, European Molecular Biology Laboratory (EMBL), Heidelberg, Germany. joachim.weischenfeldt@bric.ku.dk., Beroukhim R; The Broad Institute of MIT and Harvard, Cambridge, MA, USA. rameen@broadinstitute.org.; Bioinformatics and Integrative Genomics, Harvard University, Cambridge, MA, USA. rameen@broadinstitute.org.; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA. rameen@broadinstitute.org., Martincorena I; Wellcome Trust Sanger Institute, Hinxton, UK. im3@sanger.ac.uk., Pedersen JS; Department of Molecular Medicine (MOMA), Aarhus University Hospital, Aarhus, Denmark. jakob.skou@clin.au.dk.; Bioinformatics Research Centre (BiRC), Aarhus University, Aarhus, Denmark. jakob.skou@clin.au.dk., Getz G; The Broad Institute of MIT and Harvard, Cambridge, MA, USA. gadgetz@broadinstitute.org.; Center for Cancer Research, Massachusetts General Hospital, Charlestown, MA, USA. gadgetz@broadinstitute.org.; Harvard Medical School, Boston, MA, USA. gadgetz@broadinstitute.org.; Department of Pathology, Massachusetts General Hospital, Boston, MA, USA. gadgetz@broadinstitute.org.
Publikováno v:
Nature [Nature] 2023 Feb; Vol. 614 (7948), pp. E40.
Autor:
Li Y; Cancer Genome Project, Wellcome Trust Sanger Institute, Hinxton, UK.; Totient Inc, Cambridge, MA, USA., Roberts ND; Cancer Genome Project, Wellcome Trust Sanger Institute, Hinxton, UK., Wala JA; The Broad Institute of Harvard and MIT, Cambridge, MA, USA.; Bioinformatics and Integrative Genomics, Harvard University, Cambridge, MA, USA.; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA., Shapira O; The Broad Institute of Harvard and MIT, Cambridge, MA, USA.; Bioinformatics and Integrative Genomics, Harvard University, Cambridge, MA, USA.; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA., Schumacher SE; The Broad Institute of Harvard and MIT, Cambridge, MA, USA.; Bioinformatics and Integrative Genomics, Harvard University, Cambridge, MA, USA.; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA., Kumar K; The Broad Institute of Harvard and MIT, Cambridge, MA, USA.; Bioinformatics and Integrative Genomics, Harvard University, Cambridge, MA, USA.; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA., Khurana E; Weill Cornell Medical College, New York, NY, USA., Waszak S; European Molecular Biology Laboratory, Genome Biology Unit, Heidelberg, Germany., Korbel JO; European Molecular Biology Laboratory, Genome Biology Unit, Heidelberg, Germany., Haber JE; Department of Molecular Biology, Rosenstiel Basic Medical Sciences Research Center, Brandeis University, Waltham, MA, USA., Imielinski M; New York Genome Center, New York, NY, USA., Weischenfeldt J; Biotech Research & Innovation Centre (BRIC), The Finsen Laboratory, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark. joachim.weischenfeldt@bric.ku.dk., Beroukhim R; The Broad Institute of Harvard and MIT, Cambridge, MA, USA. rameen_beroukhim@dfci.harvard.edu.; Bioinformatics and Integrative Genomics, Harvard University, Cambridge, MA, USA. rameen_beroukhim@dfci.harvard.edu.; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA. rameen_beroukhim@dfci.harvard.edu., Campbell PJ; Cancer Genome Project, Wellcome Trust Sanger Institute, Hinxton, UK. pc8@sanger.ac.uk.; Department of Haematology, University of Cambridge, Cambridge, UK. pc8@sanger.ac.uk.
Publikováno v:
Nature [Nature] 2023 Feb; Vol. 614 (7948), pp. E38.
Autor:
Tan KT; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Genetics, Harvard Medical School, Boston, MA, USA., Kim H; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Genetics, Harvard Medical School, Boston, MA, USA., Carrot-Zhang J; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Genetics, Harvard Medical School, Boston, MA, USA., Zhang Y; Department of Genetics, Harvard Medical School, Boston, MA, USA., Kim WJ; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Kugener G; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Wala JA; Department of Medicine, University of California San Francisco, San Francisco, CA, USA., Howard TP; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Chi YY; Department of Pediatrics, University of Southern California, Los Angeles, CA, USA., Beroukhim R; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Li H; Biostatistics and Computational Biology, Dana-Farber Cancer Institute, Boston, MA, USA., Ha G; Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA., Alper SL; Department of Medicine, Beth Israel Deaconess Medical Center, Boston, MA, USA., Perlman EJ; Department of Pathology, Northwestern University, Chicago, IL, USA., Mullen EA; Department of Hematology and Oncology, Boston Children's Hospital, Boston, MA, USA.; Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, MA, USA., Hahn WC; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA. william_hahn@dfci.harvard.edu.; Broad Institute of MIT and Harvard, Cambridge, MA, USA. william_hahn@dfci.harvard.edu., Meyerson M; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA. matthew_meyerson@dfci.harvard.edu.; Broad Institute of MIT and Harvard, Cambridge, MA, USA. matthew_meyerson@dfci.harvard.edu.; Department of Genetics, Harvard Medical School, Boston, MA, USA. matthew_meyerson@dfci.harvard.edu., Hong AL; Department of Pediatrics, Emory University, Atlanta, GA, USA. andrew.hong2@emory.edu.; Aflac Center for Cancer and Blood Disorders, Children's Healthcare of Atlanta, Atlanta, GA, USA. andrew.hong2@emory.edu.
Publikováno v:
Genome medicine [Genome Med] 2021 Jul 14; Vol. 13 (1), pp. 114. Date of Electronic Publication: 2021 Jul 14.
Distinct Classes of Complex Structural Variation Uncovered across Thousands of Cancer Genome Graphs.
Autor:
Hadi K; Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, NY 10021, USA; New York Genome Center, New York, NY 10013, USA., Yao X; Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, NY 10021, USA; New York Genome Center, New York, NY 10013, USA; Tri-institutional PhD Program in Computational Biology and Medicine, Weill Cornell Medicine, New York, NY 10021, USA., Behr JM; Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, NY 10021, USA; New York Genome Center, New York, NY 10013, USA; Tri-institutional PhD Program in Computational Biology and Medicine, Weill Cornell Medicine, New York, NY 10021, USA., Deshpande A; Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, NY 10021, USA; New York Genome Center, New York, NY 10013, USA; Tri-institutional PhD Program in Computational Biology and Medicine, Weill Cornell Medicine, New York, NY 10021, USA., Xanthopoulakis C; Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, NY 10021, USA., Tian H; Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, NY 10021, USA; New York Genome Center, New York, NY 10013, USA., Kudman S; Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, NY 10021, USA; Englander Institute for Precision Medicine, Weill Cornell Medicine, New York, NY 10021, USA., Rosiene J; Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, NY 10021, USA; New York Genome Center, New York, NY 10013, USA., Darmofal M; Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, NY 10021, USA; New York Genome Center, New York, NY 10013, USA; Tri-institutional PhD Program in Computational Biology and Medicine, Weill Cornell Medicine, New York, NY 10021, USA., DeRose J; New York Genome Center, New York, NY 10013, USA., Mortensen R; New York Genome Center, New York, NY 10013, USA., Adney EM; Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, NY 10021, USA; New York Genome Center, New York, NY 10013, USA., Shaiber A; Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, NY 10021, USA; New York Genome Center, New York, NY 10013, USA; Englander Institute for Precision Medicine, Weill Cornell Medicine, New York, NY 10021, USA., Gajic Z; New York Genome Center, New York, NY 10013, USA., Sigouros M; Englander Institute for Precision Medicine, Weill Cornell Medicine, New York, NY 10021, USA., Eng K; Englander Institute for Precision Medicine, Weill Cornell Medicine, New York, NY 10021, USA; Institute for Computational Biomedicine, Weill Cornell Medicine, New York, NY 10021, USA., Wala JA; Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA; Departments of Medical Oncology and Cancer Biology, Dana-Farber Cancer Institute, Boston, MA 02215, USA; School of Medicine, University of California, San Francisco, San Francisco, CA 94143, USA., Wrzeszczyński KO; New York Genome Center, New York, NY 10013, USA., Arora K; New York Genome Center, New York, NY 10013, USA., Shah M; New York Genome Center, New York, NY 10013, USA., Emde AK; New York Genome Center, New York, NY 10013, USA., Felice V; New York Genome Center, New York, NY 10013, USA., Frank MO; New York Genome Center, New York, NY 10013, USA; Laboratory of Molecular Neuro-Oncology and Howard Hughes Medical Institute, The Rockefeller University, New York, NY 10065, USA., Darnell RB; New York Genome Center, New York, NY 10013, USA; Laboratory of Molecular Neuro-Oncology and Howard Hughes Medical Institute, The Rockefeller University, New York, NY 10065, USA., Ghandi M; Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA., Huang F; Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA; School of Medicine, University of California, San Francisco, San Francisco, CA 94143, USA., Dewhurst S; Laboratory of Cell Biology and Genetics, The Rockefeller University, New York, NY 10065, USA., Maciejowski J; Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA., de Lange T; Laboratory of Cell Biology and Genetics, The Rockefeller University, New York, NY 10065, USA., Setton J; Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA., Riaz N; Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA; Immunogenomics and Precision Oncology Platform, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA., Reis-Filho JS; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA; Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA., Powell S; Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA., Knowles DA; New York Genome Center, New York, NY 10013, USA; Department of Computer Science, Columbia University, New York, NY 10027, USA., Reznik E; Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA., Mishra B; Departments of Computer Science, Mathematics and Cell Biology, Courant Institute and NYU School of Medicine, New York University, New York, NY 10012, USA., Beroukhim R; Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA; Departments of Medical Oncology and Cancer Biology, Dana-Farber Cancer Institute, Boston, MA 02215, USA., Zody MC; New York Genome Center, New York, NY 10013, USA., Robine N; New York Genome Center, New York, NY 10013, USA., Oman KM; Divisions of Human Biology and Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA., Sanchez CA; Divisions of Human Biology and Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA., Kuhner MK; Department of Genome Sciences, University of Washington, Seattle, WA 98195, USA., Smith LP; Department of Bioengineering, University of Washington, Seattle, WA 98195, USA., Galipeau PC; Divisions of Human Biology and Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA., Paulson TG; Divisions of Human Biology and Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA., Reid BJ; Divisions of Human Biology and Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA; Department of Genome Sciences, University of Washington, Seattle, WA 98195, USA., Li X; Divisions of Human Biology and Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA., Wilkes D; Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, NY 10021, USA; Englander Institute for Precision Medicine, Weill Cornell Medicine, New York, NY 10021, USA., Sboner A; Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, NY 10021, USA; Englander Institute for Precision Medicine, Weill Cornell Medicine, New York, NY 10021, USA; Institute for Computational Biomedicine, Weill Cornell Medicine, New York, NY 10021, USA., Mosquera JM; Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, NY 10021, USA; Englander Institute for Precision Medicine, Weill Cornell Medicine, New York, NY 10021, USA., Elemento O; Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, NY 10021, USA; Englander Institute for Precision Medicine, Weill Cornell Medicine, New York, NY 10021, USA; Institute for Computational Biomedicine, Weill Cornell Medicine, New York, NY 10021, USA., Imielinski M; Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, NY 10021, USA; New York Genome Center, New York, NY 10013, USA; Englander Institute for Precision Medicine, Weill Cornell Medicine, New York, NY 10021, USA; Institute for Computational Biomedicine, Weill Cornell Medicine, New York, NY 10021, USA. Electronic address: mski@mskilab.org.
Publikováno v:
Cell [Cell] 2020 Oct 01; Vol. 183 (1), pp. 197-210.e32.
Autor:
Rodriguez-Martin B; Department of Zoology, Genetics and Physical Anthropology, Universidade de Santiago de Compostela, Santiago de Compostela, Spain.; Biomedical Research Centre (CINBIO), University of Vigo, Vigo, Spain.; Centre for Research in Molecular Medicine and Chronic Diseases (CIMUS), Universidade de Santiago de Compostela, Santiago de Compostela, Spain., Alvarez EG; Department of Zoology, Genetics and Physical Anthropology, Universidade de Santiago de Compostela, Santiago de Compostela, Spain.; Biomedical Research Centre (CINBIO), University of Vigo, Vigo, Spain.; Centre for Research in Molecular Medicine and Chronic Diseases (CIMUS), Universidade de Santiago de Compostela, Santiago de Compostela, Spain., Baez-Ortega A; Transmissible Cancer Group, Department of Veterinary Medicine, University of Cambridge, Cambridge, UK., Zamora J; Department of Zoology, Genetics and Physical Anthropology, Universidade de Santiago de Compostela, Santiago de Compostela, Spain.; Centre for Research in Molecular Medicine and Chronic Diseases (CIMUS), Universidade de Santiago de Compostela, Santiago de Compostela, Spain.; The Biomedical Research Centre (CINBIO), Universidade de Vigo, Vigo, Spain.; Wellcome Sanger Institute, Wellcome Genome Campus, Cambridge, UK., Supek F; Genome Data Science, Institute for Research in Biomedicine (IRB Barcelona), The Barcelona Institute of Science and Technology (BIST), Barcelona, Spain.; Institucio Catalana de Recerca i Estudis Avançats (ICREA), Barcelona, Spain., Demeulemeester J; The Francis Crick Institute, London, UK.; Department of Human Genetics, University of Leuven, Leuven, Belgium., Santamarina M; Department of Zoology, Genetics and Physical Anthropology, Universidade de Santiago de Compostela, Santiago de Compostela, Spain.; Biomedical Research Centre (CINBIO), University of Vigo, Vigo, Spain.; Genomes and Disease, Centre for Research in Molecular Medicine and Chronic Diseases (CIMUS), Universidade de Santiago de Compostela, Santiago de Compostela, Spain., Ju YS; Graduate School of Medical Science and Engineering, Korea Advanced Institute of Science and Technology, Daejeon, South Korea.; Cancer Ageing and Somatic Mutation Programme, Wellcome Sanger Institute, Cambridge, UK., Temes J; Department of Zoology, Genetics and Physical Anthropology, Universidade de Santiago de Compostela, Santiago de Compostela, Spain.; Centre for Research in Molecular Medicine and Chronic Diseases (CIMUS), Universidade de Santiago de Compostela, Santiago de Compostela, Spain., Garcia-Souto D; Genomes and Disease, Centre for Research in Molecular Medicine and Chronic Diseases (CIMUS), Universidade de Santiago de Compostela, Santiago de Compostela, Spain., Detering H; Biomedical Research Centre (CINBIO), University of Vigo, Vigo, Spain.; Department of Biochemistry, Genetics and Immunology, University of Vigo, Vigo, Spain.; Galicia Sur Health Research Institute, Vigo, Spain., Li Y; Wellcome Sanger Institute, Wellcome Genome Campus, Cambridge, UK., Rodriguez-Castro J; Genomes and Disease, Centre for Research in Molecular Medicine and Chronic Diseases (CIMUS), Universidade de Santiago de Compostela, Santiago de Compostela, Spain., Dueso-Barroso A; Faculty of Science and Technology, University of Vic-Central University of Catalonia (UVic-UCC), Vic, Spain.; Barcelona Supercomputing Center (BSC), Barcelona, Spain., Bruzos AL; Department of Zoology, Genetics and Physical Anthropology, Universidade de Santiago de Compostela, Santiago de Compostela, Spain.; Biomedical Research Centre (CINBIO), University of Vigo, Vigo, Spain.; Genomes and Disease, Centre for Research in Molecular Medicine and Chronic Diseases (CIMUS), Universidade de Santiago de Compostela, Santiago de Compostela, Spain., Dentro SC; The Francis Crick Institute, London, UK.; Experimental Cancer Genetics, Wellcome Sanger Institute, Cambridge, UK.; Oxford Big Data Institute, University of Oxford, Oxford, UK., Blanco MG; DNA Repair and Genome Integrity, Centre for Research in Molecular Medicine and Chronic Diseases (CIMUS), Universidade de Santiago de Compostela, Santiago de Compostela, Spain.; Department of Biochemistry and Molecular Biology, Universidade de Santiago de Compostela, Santiago de Compostela, Spain., Contino G; Medical Research Council (MRC) Cancer Unit, University of Cambridge, Cambridge, UK., Ardeljan D; Department of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, Baltimore, MD, USA., Tojo M; The Biomedical Research Centre (CINBIO), Universidade de Vigo, Vigo, Spain.; Department of Biochemistry, Genetics and Immunology, University of Vigo, Vigo, Spain., Roberts ND; Wellcome Sanger Institute, Wellcome Genome Campus, Cambridge, UK., Zumalave S; Department of Zoology, Genetics and Physical Anthropology, Universidade de Santiago de Compostela, Santiago de Compostela, Spain.; Genomes and Disease, Centre for Research in Molecular Medicine and Chronic Diseases (CIMUS), Universidade de Santiago de Compostela, Santiago de Compostela, Spain., Edwards PA; University of Cambridge, Cambridge, UK.; Li Ka Shing Centre, Cancer Research UK Cambridge Institute, University of Cambridge, Cambridge, UK., Weischenfeldt J; European Molecular Biology Laboratory (EMBL), Genome Biology Unit, Heidelberg, Germany.; Finsen Laboratory and Biotech Research & Innovation Centre (BRIC), University of Copenhagen, Copenhagen, Denmark.; Department of Urology, Charité Universitätsmedizin Berlin, Berlin, Germany., Puiggròs M; Barcelona Supercomputing Center (BSC), Barcelona, Spain., Chong Z; Department of Bioinformatics and Computational Biology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.; Department of Genetics and Informatics Institute, University of Alabama at Birmingham (UAB) School of Medicine, Birmingham, AL, USA., Chen K; University of Texas MD Anderson Cancer Center, Houston, TX, USA., Lee EA; Division of Genetics and Genomics, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA., Wala JA; The Broad Institute of Harvard and MIT, Cambridge, MA, USA.; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA.; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.; Harvard Medical School, Boston, MA, USA., Raine KM; Cancer Ageing and Somatic Mutation Programme, Wellcome Sanger Institute, Cambridge, UK., Butler A; Cancer Ageing and Somatic Mutation Programme, Wellcome Sanger Institute, Cambridge, UK., Waszak SM; European Molecular Biology Laboratory (EMBL), Genome Biology Unit, Heidelberg, Germany., Navarro FCP; Program in Computational Biology and Bioinformatics, Yale University, New Haven, CT, USA.; Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT, USA.; Department of Computer Science, Yale University, New Haven, CT, USA., Schumacher SE; The Broad Institute of Harvard and MIT, Cambridge, MA, USA.; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA.; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA., Monlong J; Department of Human Genetics, McGill University, Montreal, Québec, Canada., Maura F; Cancer Ageing and Somatic Mutation Programme, Wellcome Sanger Institute, Cambridge, UK.; Department of Oncology and Onco-Hematology, University of Milan, Milan, Italy.; Department of Medical Oncology and Hematology, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy., Bolli N; Department of Oncology and Onco-Hematology, University of Milan, Milan, Italy.; Department of Medical Oncology and Hematology, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy., Bourque G; Canadian Center for Computational Genomics, McGill University, Montreal, Quebec, Canada., Gerstein M; Program in Computational Biology and Bioinformatics, Yale University, New Haven, CT, USA.; Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT, USA.; Department of Computer Science, Yale University, New Haven, CT, USA., Park PJ; Department of Biomedical Informatics, Harvard Medical School, Boston, MA, USA.; Ludwig Center at Harvard, Boston, MA, USA., Wedge DC; Cancer Ageing and Somatic Mutation Programme, Wellcome Sanger Institute, Cambridge, UK.; Experimental Cancer Genetics, Wellcome Sanger Institute, Cambridge, UK.; Oxford NIHR Biomedical Research Centre, Oxford, UK., Beroukhim R; The Broad Institute of Harvard and MIT, Cambridge, MA, USA.; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.; Harvard Medical School, Boston, MA, USA., Torrents D; Institucio Catalana de Recerca i Estudis Avançats (ICREA), Barcelona, Spain.; Barcelona Supercomputing Center (BSC), Barcelona, Spain., Korbel JO; European Molecular Biology Laboratory (EMBL), Genome Biology Unit, Heidelberg, Germany.; European Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI), Cambridge, UK., Martincorena I; Wellcome Sanger Institute, Wellcome Genome Campus, Cambridge, UK., Fitzgerald RC; Medical Research Council (MRC) Cancer Unit, University of Cambridge, Cambridge, UK., Van Loo P; The Francis Crick Institute, London, UK.; Department of Human Genetics, University of Leuven, Leuven, Belgium., Kazazian HH; Department of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, Baltimore, MD, USA., Burns KH; Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, Baltimore, MD, USA.; McKusick-Nathans Institute of Genetic Medicine, Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins University School of Medicine, Baltimore, MD, USA., Campbell PJ; Wellcome Sanger Institute, Wellcome Genome Campus, Cambridge, UK. pc8@sanger.ac.uk.; Department of Haematology, University of Cambridge, Cambridge, UK. pc8@sanger.ac.uk., Tubio JMC; Department of Zoology, Genetics and Physical Anthropology, Universidade de Santiago de Compostela, Santiago de Compostela, Spain. jose.mc.tubio@usc.es.; Biomedical Research Centre (CINBIO), University of Vigo, Vigo, Spain. jose.mc.tubio@usc.es.; Centre for Research in Molecular Medicine and Chronic Diseases (CIMUS), Universidade de Santiago de Compostela, Santiago de Compostela, Spain. jose.mc.tubio@usc.es.; Cancer Ageing and Somatic Mutation Programme, Wellcome Sanger Institute, Cambridge, UK. jose.mc.tubio@usc.es.
Publikováno v:
Nature genetics [Nat Genet] 2020 Mar; Vol. 52 (3), pp. 306-319. Date of Electronic Publication: 2020 Feb 05.
Autor:
Li Y; Cancer Genome Project, Wellcome Trust Sanger Institute, Hinxton, UK.; Totient Inc, Cambridge, MA, USA., Roberts ND; Cancer Genome Project, Wellcome Trust Sanger Institute, Hinxton, UK., Wala JA; The Broad Institute of Harvard and MIT, Cambridge, MA, USA.; Bioinformatics and Integrative Genomics, Harvard University, Cambridge, MA, USA.; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA., Shapira O; The Broad Institute of Harvard and MIT, Cambridge, MA, USA.; Bioinformatics and Integrative Genomics, Harvard University, Cambridge, MA, USA.; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA., Schumacher SE; The Broad Institute of Harvard and MIT, Cambridge, MA, USA.; Bioinformatics and Integrative Genomics, Harvard University, Cambridge, MA, USA.; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA., Kumar K; The Broad Institute of Harvard and MIT, Cambridge, MA, USA.; Bioinformatics and Integrative Genomics, Harvard University, Cambridge, MA, USA.; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA., Khurana E; Weill Cornell Medical College, New York, NY, USA., Waszak S; European Molecular Biology Laboratory, Genome Biology Unit, Heidelberg, Germany., Korbel JO; European Molecular Biology Laboratory, Genome Biology Unit, Heidelberg, Germany., Haber JE; Department of Molecular Biology, Rosenstiel Basic Medical Sciences Research Center, Brandeis University, Waltham, MA, USA., Imielinski M; New York Genome Center, New York, NY, USA., Weischenfeldt J; Biotech Research & Innovation Centre (BRIC), The Finsen Laboratory, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark. joachim.weischenfeldt@bric.ku.dk., Beroukhim R; The Broad Institute of Harvard and MIT, Cambridge, MA, USA. rameen_beroukhim@dfci.harvard.edu.; Bioinformatics and Integrative Genomics, Harvard University, Cambridge, MA, USA. rameen_beroukhim@dfci.harvard.edu.; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA. rameen_beroukhim@dfci.harvard.edu., Campbell PJ; Cancer Genome Project, Wellcome Trust Sanger Institute, Hinxton, UK. pc8@sanger.ac.uk.; Department of Haematology, University of Cambridge, Cambridge, UK. pc8@sanger.ac.uk.
Publikováno v:
Nature [Nature] 2020 Feb; Vol. 578 (7793), pp. 112-121. Date of Electronic Publication: 2020 Feb 05.
Autor:
Rheinbay E; The Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Center for Cancer Research, Massachusetts General Hospital, Charlestown, MA, USA.; Harvard Medical School, Boston, MA, USA., Nielsen MM; Department of Molecular Medicine (MOMA), Aarhus University Hospital, Aarhus, Denmark., Abascal F; Wellcome Trust Sanger Institute, Hinxton, UK., Wala JA; The Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Bioinformatics and Integrative Genomics, Harvard University, Cambridge, MA, USA., Shapira O; The Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA., Tiao G; The Broad Institute of MIT and Harvard, Cambridge, MA, USA., Hornshøj H; Department of Molecular Medicine (MOMA), Aarhus University Hospital, Aarhus, Denmark., Hess JM; The Broad Institute of MIT and Harvard, Cambridge, MA, USA., Juul RI; Department of Molecular Medicine (MOMA), Aarhus University Hospital, Aarhus, Denmark., Lin Z; The Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Harvard University, Cambridge, MA, USA., Feuerbach L; Division of Applied Bioinformatics, German Cancer Research Center (DKFZ), Heidelberg, Germany., Sabarinathan R; Institute for Research in Biomedicine (IRB Barcelona), The Barcelona Institute of Science and Technology, Barcelona, Spain.; Research Program on Biomedical Informatics, Universitat Pompeu Fabra, Barcelona, Spain., Madsen T; Department of Molecular Medicine (MOMA), Aarhus University Hospital, Aarhus, Denmark., Kim J; The Broad Institute of MIT and Harvard, Cambridge, MA, USA., Mularoni L; Institute for Research in Biomedicine (IRB Barcelona), The Barcelona Institute of Science and Technology, Barcelona, Spain.; Research Program on Biomedical Informatics, Universitat Pompeu Fabra, Barcelona, Spain., Shuai S; Computational Biology Program, Ontario Institute for Cancer Research, Toronto, Ontario, Canada.; Ontario Institute for Cancer Research, Toronto, Ontario, Canada., Lanzós A; Department for BioMedical Research, University of Bern, Bern, Switzerland.; Graduate School of Cellular and Biomedical Sciences, University of Bern, Bern, Switzerland.; Department of Medical Oncology, Bern University Hospital, University of Bern, Bern, Switzerland., Herrmann C; Division of Theoretical Bioinformatics, German Cancer Research Center (DKFZ), Heidelberg, Germany.; Bioquant Center, Institute of Pharmacy and Molecular Biotechnology, University of Heidelberg, Heidelberg, Germany., Maruvka YE; The Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Center for Cancer Research, Massachusetts General Hospital, Charlestown, MA, USA., Shen C; Department of Cell Biology, Harvard Medical School, Boston, MA, USA.; cBio Center, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA., Amin SB; Department of Genomic Medicine, University of Texas MD Anderson Cancer Center, Houston, TX, USA.; Graduate Program in Structural and Computational Biology and Molecular Biophysics, Baylor College of Medicine, Houston, TX, USA., Bandopadhayay P; The Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA., Bertl J; Department of Molecular Medicine (MOMA), Aarhus University Hospital, Aarhus, Denmark., Boroevich KA; Laboratory for Medical Science Mathematics, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan., Busanovich J; The Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA., Carlevaro-Fita J; Department for BioMedical Research, University of Bern, Bern, Switzerland.; Graduate School of Cellular and Biomedical Sciences, University of Bern, Bern, Switzerland.; Department of Medical Oncology, Bern University Hospital, University of Bern, Bern, Switzerland., Chakravarty D; Department of Genitourinary Medical Oncology - Research, Division of Cancer Medicine, University of Texas MD Anderson Cancer Center, Houston, TX, USA.; Department of Urology, Icahn school of Medicine at Mount Sinai, New York, NY, USA., Chan CWY; Division of Theoretical Bioinformatics, German Cancer Research Center (DKFZ), Heidelberg, Germany.; Faculty of Biosciences, Heidelberg University, Heidelberg, Germany., Craft D; Department of Radiation Oncology, Harvard Medical School, Massachusetts General Hospital, Boston, MA, USA., Dhingra P; Department of Physiology and Biophysics, Weill Cornell Medicine, New York, NY, USA.; Institute for Computational Biomedicine, Weill Cornell Medicine, New York, NY, USA., Diamanti K; Science for Life Laboratory, Department of Cell and Molecular Biology, Uppsala University, Uppsala, Sweden., Fonseca NA; European Bioinformatics Institute, European Molecular Biology Laboratory, Hinxton, UK., Gonzalez-Perez A; Institute for Research in Biomedicine (IRB Barcelona), The Barcelona Institute of Science and Technology, Barcelona, Spain.; Research Program on Biomedical Informatics, Universitat Pompeu Fabra, Barcelona, Spain., Guo Q; Bioinformatics Research Centre (BiRC), Aarhus University, Aarhus, Denmark., Hamilton MP; Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX, USA., Haradhvala NJ; The Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Center for Cancer Research, Massachusetts General Hospital, Charlestown, MA, USA., Hong C; Division of Applied Bioinformatics, German Cancer Research Center (DKFZ), Heidelberg, Germany.; Faculty of Biosciences, Heidelberg University, Heidelberg, Germany., Isaev K; Computational Biology Program, Ontario Institute for Cancer Research, Toronto, Ontario, Canada.; Department of Medical Biophysics, University of Toronto, Toronto, Ontario, Canada., Johnson TA; Laboratory for Medical Science Mathematics, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan., Juul M; Department of Molecular Medicine (MOMA), Aarhus University Hospital, Aarhus, Denmark., Kahles A; Division of Computational Biology, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Kahraman A; Institute of Molecular Life Sciences and Swiss Institute of Bioinformatics, University of Zurich, Zurich, Switzerland., Kim Y; Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea., Komorowski J; Science for Life Laboratory, Department of Cell and Molecular Biology, Uppsala University, Uppsala, Sweden.; Institute of Computer Science, Polish Academy of Sciences, Warsaw, Poland., Kumar K; The Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA., Kumar S; Program in Computational Biology and Bioinformatics, Yale University, New Haven, CT, USA., Lee D; Program in Computational Biology and Bioinformatics, Yale University, New Haven, CT, USA., Lehmann KV; Division of Computational Biology, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Li Y; SBGD Inc, Cambridge, MA, USA.; Department of Haematology, University of Cambridge, Cambridge, UK., Liu EM; Department of Physiology and Biophysics, Weill Cornell Medicine, New York, NY, USA.; Institute for Computational Biomedicine, Weill Cornell Medicine, New York, NY, USA., Lochovsky L; Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT, USA., Park K; Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea., Pich O; Institute for Research in Biomedicine (IRB Barcelona), The Barcelona Institute of Science and Technology, Barcelona, Spain.; Research Program on Biomedical Informatics, Universitat Pompeu Fabra, Barcelona, Spain., Roberts ND; Department of Haematology, University of Cambridge, Cambridge, UK., Saksena G; The Broad Institute of MIT and Harvard, Cambridge, MA, USA., Schumacher SE; The Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA., Sidiropoulos N; Biotech Research & Innovation Centre (BRIC), The Finsen Laboratory, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark., Sieverling L; Division of Applied Bioinformatics, German Cancer Research Center (DKFZ), Heidelberg, Germany.; Faculty of Biosciences, Heidelberg University, Heidelberg, Germany., Sinnott-Armstrong N; Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA., Stewart C; The Broad Institute of MIT and Harvard, Cambridge, MA, USA., Tamborero D; Institute for Research in Biomedicine (IRB Barcelona), The Barcelona Institute of Science and Technology, Barcelona, Spain.; Research Program on Biomedical Informatics, Universitat Pompeu Fabra, Barcelona, Spain., Tubio JMC; Department of Zoology, Genetics and Physical Anthropology, Universidade de Santiago de Compostela, Santiago de Compostela, Spain.; Centre for Research in Molecular Medicine and Chronic Diseases (CIMUS), Universidade de Santiago de Compostela, Santiago de Compostela, Spain.; The Biomedical Research Centre (CINBIO), Universidade de Vigo, Vigo, Spain., Umer HM; Science for Life Laboratory, Department of Cell and Molecular Biology, Uppsala University, Uppsala, Sweden.; Department of Oncology-Pathology, Science for Life Laboratory, Karolinska Institute, Stockholm, Sweden., Uusküla-Reimand L; Genetics and Genome Biology Program, SickKids Research Institute, Toronto, Ontario, Canada.; Department of Gene Technology, Tallinn University of Technology, Tallinn, Estonia., Wadelius C; Science for Life Laboratory, Department of Immunology, Genetics and Pathology, Uppsala University, Uppsala, Sweden., Wadi L; Computational Biology Program, Ontario Institute for Cancer Research, Toronto, Ontario, Canada., Yao X; New York Genome Center, New York, NY, USA., Zhang CZ; Department of Biostatistics and Computational Biology, Dana-Farber Cancer Institute, Boston, MA, USA.; Department of Biomedical Informatics, Harvard Medical School, Boston, MA, USA., Zhang J; Program in Computational Biology and Bioinformatics, Yale University, New Haven, CT, USA., Haber JE; Department of Biology and Rosenstiel Basic Medical Sciences Research Center, Brandeis University, Waltham, MA, USA., Hobolth A; Bioinformatics Research Centre (BiRC), Aarhus University, Aarhus, Denmark., Imielinski M; New York Genome Center, New York, NY, USA.; Department of Pathology and Laboratory Medicine, and Englander Institute for Precision Medicine, and Institute for Computational Biomedicine, and Meyer Cancer Center, Weill Cornell Medicine, New York, NY, USA., Kellis M; The Broad Institute of MIT and Harvard, Cambridge, MA, USA.; MIT Computer Science and Artificial Intelligence Laboratory, Cambridge, MA, USA., Lawrence MS; The Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Center for Cancer Research, Massachusetts General Hospital, Charlestown, MA, USA., von Mering C; Institute of Molecular Life Sciences and Swiss Institute of Bioinformatics, University of Zurich, Zurich, Switzerland., Nakagawa H; Laboratory for Cancer Genomics, RIKEN Center for Integrative Medical Sciences, Tokyo, Japan., Raphael BJ; Department of Computer Science, Princeton University, Princeton, NJ, USA., Rubin MA; Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, NY, USA.; Englander Institute for Precision Medicine, Weill Cornell Medicine, New York, NY, USA.; Meyer Cancer Center, Weill Cornell Medicine, New York, NY, USA., Sander C; Department of Cell Biology, Harvard Medical School, Boston, MA, USA.; cBio Center, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA., Stein LD; Computational Biology Program, Ontario Institute for Cancer Research, Toronto, Ontario, Canada.; Ontario Institute for Cancer Research, Toronto, Ontario, Canada., Stuart JM; Center for Biomolecular Science and Engineering, University of California at Santa Cruz, Santa Cruz, CA, USA., Tsunoda T; Laboratory for Medical Science Mathematics, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan.; Department of Medical Science Mathematics, Medical Research Institute, Tokyo Medical and Dental University, Tokyo, Japan.; Laboratory for Medical Science Mathematics, Department of Biological Sciences, Graduate School of Science, The University of Tokyo, Tokyo, Japan., Wheeler DA; Human Genome Sequencing Center, Baylor College of Medicine, Houston, TX, USA., Johnson R; Department for BioMedical Research, University of Bern, Bern, Switzerland.; Department of Medical Oncology, Bern University Hospital, University of Bern, Bern, Switzerland., Reimand J; Computational Biology Program, Ontario Institute for Cancer Research, Toronto, Ontario, Canada.; Department of Medical Biophysics, University of Toronto, Toronto, Ontario, Canada., Gerstein M; Program in Computational Biology and Bioinformatics, Yale University, New Haven, CT, USA.; Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT, USA.; Department of Computer Science, Yale University, New Haven, CT, USA., Khurana E; Department of Physiology and Biophysics, Weill Cornell Medicine, New York, NY, USA.; Institute for Computational Biomedicine, Weill Cornell Medicine, New York, NY, USA.; Englander Institute for Precision Medicine, Weill Cornell Medicine, New York, NY, USA.; Meyer Cancer Center, Weill Cornell Medicine, New York, NY, USA., Campbell PJ; Wellcome Trust Sanger Institute, Hinxton, UK.; Department of Haematology, University of Cambridge, Cambridge, UK., López-Bigas N; Institute for Research in Biomedicine (IRB Barcelona), The Barcelona Institute of Science and Technology, Barcelona, Spain.; Research Program on Biomedical Informatics, Universitat Pompeu Fabra, Barcelona, Spain.; 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The Broad Institute of MIT and Harvard, Cambridge, MA, USA. gadgetz@broadinstitute.org.; Center for Cancer Research, Massachusetts General Hospital, Charlestown, MA, USA. gadgetz@broadinstitute.org.; Harvard Medical School, Boston, MA, USA. gadgetz@broadinstitute.org.; Department of Pathology, Massachusetts General Hospital, Boston, MA, USA. gadgetz@broadinstitute.org.
Publikováno v:
Nature [Nature] 2020 Feb; Vol. 578 (7793), pp. 102-111. Date of Electronic Publication: 2020 Feb 05.