Common Variants at the 19p13.1 and ZNF365 Loci Are Associated with ER Subtypes of Breast Cancer and Ovarian Cancer Risk in BRCA1 and BRCA2 Mutation Carriers

Autor: Couch, F.J., Gaudet, M.M., Antoniou, A.C., Ramus, S.J., Kuchenbaecker, K.B., Soucy, P., Beesley, J., Chen, X.Q., Wang, X.S., Kirchhoff, T., McGuffog, L., Barrowdale, D., Lee, A., Healey, S., Sinilnikova, O.M., Andrulis, I.L., Ozcelik, H., Mulligan, A.M., Thomassen, M., Gerdes, A.M., Jensen, U.B., Skytte, A.B., Kruse, T.A., Caligo, M.A., Wachenfeldt, A. von, Barbany-Bustinza, G., Loman, N., Soller, M., Ehrencrona, H., Karlsson, P., Nathanson, K.L., Rebbeck, T.R., Domchek, S.M., Jakubowska, A., Lubinski, J., Jaworska, K., Durda, K., Zlowocka, E., Huzarski, T., Byrski, T., Gronwald, J., Cybulski, C., Gorski, B., Osorio, A., Duran, M., Tejada, M.I., Benitez, J., Hamann, U., Hogervorst, F.B.L., Os, T.A. van, Leeuwen, F.E. van, Meijers-Heijboer, H.E.J., Wijnen, J., Blok, M.J., Kets, M., Hooning, M.J., Oldenburg, R.A., Ausems, M.G.E.M., Peock, S., Frost, D., Ellis, S.D., Platte, R., Fineberg, E., Evans, D.G., Jacobs, C., Eeles, R.A., Adlard, J., Davidson, R., Eccles, D.M., Cole, T., Cook, J., Paterson, J., Brewer, C., Douglas, F., Hodgson, S.V., Morrison, P.J., Walker, L., Porteous, M.E., Kennedy, M.J., Side, L.E., Bove, B., Godwin, A.K., Stoppa-Lyonnet, D., Fassy-Colcombet, M., Castera, L., Cornelis, F., Mazoyer, S., Leone, M., Boutry-Kryza, N., Bressac-de Paillerets, B., Caron, O., Pujol, P., Coupier, I., Delnatte, C., Akloul, L., Lynch, H.T., Snyder, C.L., Buys, S.S., Daly, M.B., Terry, M., Chung, W.K., John, E.M., Miron, A., Southey, M.C., Hopper, J.L., Goldgar, D.E., Singer, C.F., Rappaport, C., Tea, M.K.M., Fink-Retter, A., Hansen, T.V.O., Nielsen, F.C., Arason, A., Vijai, J., Shah, S., Sarrel, K., Robson, M.E., Piedmonte, M., Phillips, K., Basil, J., Rubinstein, W.S., Boggess, J., Wakeley, K., Ewart-Toland, A., Montagna, M., Agata, S., Imyanitov, E.N., Isaacs, C., Janavicius, R., Lazaro, C., Blanco, I., Feliubadalo, L., Brunet, J., Gayther, S.A., Pharoah, P.P.D., Odunsi, K.O., Karlan, B.Y., Walsh, C.S., Olah, E., Teo, S.H., Ganz, P.A., Beattie, M.S., Rensburg, E.J. van, Dorfling, C.M., Diez, O., Kwong, A., Schmutzler, R.K., Wappenschmidt, B., Engel, C., Meindl, A., Ditsch, N., Arnold, N., Heidemann, S., Niederacher, D., Preisler-Adams, S., Gadzicki, D., Varon-Mateeva, R., Deissler, H., Gehrig, A., Sutter, C., Kast, K., Fiebig, B., Heinritz, W., Caldes, T., Hoya, M. de la, Muranen, T.A., Nevanlinna, H., Tischkowitz, M., Spurdle, A.B., Neuhausen, S.L., Ding, Y.C., Lindor, N.M., Fredericksen, Z., Pankratz, V.S., Peterlongo, P., Manoukian, S., Peissel, B., Zaffaroni, D., Barile, M., Bernard, L., Viel, A., Giannini, G., Varesco, L., Radice, P., Greene, M.H., Mai, P.L., Easton, D.F., Chenevix-Trench, G., Offit, K., Simard, J., OCGN, SWE-BRCA, HEBON, EMBRACE, GEMO Study Collaborators, kConFab Investigators, Consortium Investigators Modifiers

Publikováno v: Couch, F J, Gaudet, M M, Antoniou, A C, Ramus, S J, Kuchenbaecker, K B, Soucy, P, Beesley, J, Chen, X Q, Wang, X S, Kirchhoff, T, McGuffog, L, Barrowdale, D, Lee, A, Healey, S, Sinilnikova, O M, Andrulis, I L, Ozcelik, H, Mulligan, A M, Thomassen, M, Gerdes, A M, Jensen, U B, Skytte, A B, Kruse, T A, Caligo, M A, von Wachenfeldt, A, Barbany-Bustinza, G, Loman, N, Soller, M, Ehrencrona, H, Karlsson, P, Nathanson, K L, Rebbeck, T R, Domchek, S M, Jakubowska, A, Lubinski, J, Jaworska, K, Durda, K, Zlowocka, E, Huzarski, T, Byrski, T, Gronwald, J, Cybulski, C, Gorski, B, Osorio, A, Duran, M, Tejada, M I, Benitez, J, Hamann, U, Hogervorst, F B L, Os, T A, van Leeuwen, F E, Meijers-Heijboer, E J, van Wijnen, J, Blok, M J, Kets, M, Hooning, M J, Oldenburg, R A, Ausems, M G E M, Peock, S, Frost, D, Ellis, S D, Platte, R, Fineberg, E, Evans, D G, Jacobs, C, Eeles, R A, Adlard, J, Davidson, R, Eccles, D M, Cole, T, Cook, J, Paterson, J, Brewer, C, Douglas, F, Hodgson, SV, Morrison, P J, Walker, L, Porteous, M E, Kennedy, M J, Side, L E, Bove, B, Godwin, A K, Stoppa-Lyonnet, D, Fassy-Colcombet, M, Castera, L, Cornelis, F, Mazoyer, S, Leone, M, Boutry-Kryza, N, Bressac-de Paillerets, B, Caron, O, Pujol, P, Coupier, I, Delnatte, C, Akloul, L, Lynch, H T, Snyder, C L, Buys, S S & Daly, M B 2012, ' Common Variants at the 19p13.1 and ZNF365 Loci Are Associated with ER Subtypes of Breast Cancer and Ovarian Cancer Risk in BRCA1 and BRCA2 Mutation Carriers ', Cancer Epidemiology Biomarkers and Prevention, vol. 21, no. 4, pp. 645-657 . https://doi.org/10.1158/1055-9965.EPI-11-0888
Couch, F J, Gaudet, M M, Antoniou, A C, Ramus, S J, Kuchenbaecker, K B, Soucy, P, Beesley, J, Chen, X, Wang, X, Kirchhoff, T, McGuffog, L, Barrowdale, D, Lee, A, Healey, S, Sinilnikova, O M, Andrulis, I L, Ozcelik, H, Mulligan, A M, Thomassen, M, Gerdes, A-M, Jensen, U B, Skytte, A-B, Kruse, T A, Caligo, M A, von Wachenfeldt, A, Barbany-Bustinza, G, Loman, N, Soller, M, Ehrencrona, H, Karlsson, P, Nathanson, K L, Rebbeck, T R, Domchek, S M, Jakubowska, A, Lubinski, J, Jaworska, K, Durda, K, Zlowocka, E, Huzarski, T, Byrski, T, Gronwald, J, Cybulski, C, Górski, B, Osorio, A, Durán, M, Tejada, M I, Benitez, J, Hamann, U, Hogervorst, F B L, van Os, T A & OCGN 2012, ' Common variants at the 19p13.1 and ZNF365 loci are associated with ER subtypes of breast cancer and ovarian cancer risk in BRCA1 and BRCA2 mutation carriers ', Cancer Epidemiology, Biomarkers & Prevention, vol. 21, no. 4, pp. 645-57 . https://doi.org/10.1158/1055-9965.EPI-11-0888
Cancer Epidemiology Biomarkers and Prevention, 21(4), 645-657. American Association for Cancer Research Inc.
Cancer Epidemiology Biomarkers & Prevention; Vol 21
Cancer Epidemiology, Biomarkers and Prevention, 21(4), 645-657
Cancer Epidemiology, Biomarkers & Prevention, 21, 4, pp. 645-57
Digital.CSIC. Repositorio Institucional del CSIC
instname
Couch, F J, Gaudet, M M, Antoniou, A C, Ramus, S J, Kuchenbaecker, K B, Soucy, P, Beesley, J, Chen, X, Wang, X, Kirchhoff, T, McGuffog, L, Barrowdale, D, Lee, A R, Healey, S, Sinilnikova, O M, Andrulis, I L, Ozcelik, H, Mulligan, A M, Thomassen, M, Gerdes, A-M A, Jensen, U B, Skytte, A-B S, Kruse, T A, Caligo, M A, von Wachenfeldt, A, Barbany-Bustinza, G, Loman, N, Soller, M, Ehrencrona, H, Karlsson, P W, Nathanson, K L, Rebbeck, T R, Domchek, S M, Jakubowska, A, Lubinski, J, Jaworska, K, Durda, K, Zlowocka, E, Huzarski, T, Byrski, T, Gronwald, J, Cybulski, C, Górski, B, Osorio, A, Durán, M, Tejada, M I, Benitez, J, Hamann, U, Hogervorst, F B L, van Os, T A & OCGN 2012, ' Common variants at the 19p13.1 and ZNF365 loci are associated with ER subtypes of breast cancer and ovarian cancer risk in BRCA1 and BRCA2 mutation carriers ', Cancer Epidemiology, Biomarkers & Prevention, vol. 21, no. 4, pp. 645-57 . https://doi.org/10.1158/1055-9965.EPI-11-0888
Cancer Epidemiology Biomarkers & Prevention, 21(4), 645-657. American Association for Cancer Research Inc.
Cancer Epidemiology, Biomarkers & Prevention, 21, 645-57
Cancer epidemiology, biomarkers & prevention, 21(4), 645-657. American Association for Cancer Research Inc.

PMCID: PMC3319317.-- et al.
[Background]: Genome-wide association studies (GWAS) identified variants at 19p13.1 and ZNF365 (10q21.2) as risk factors for breast cancer among BRCA1 and BRCA2 mutation carriers, respectively. We explored association

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b949799806fed1689a9d24c254b3c62
https://research.vumc.nl/en/publications/f7b6f7f2-aac8-4050-a221-f53efa006269

Common Breast Cancer Susceptibility Alleles and the Risk of Breast Cancer for BRCA1 and BRCA2 Mutation Carriers: Implications for Risk Prediction

Autor: Antoniou, A.C., Beesley, J., McGuffog, L., Sinilnikova, O.M., Healey, S., Neuhausen, S.L., Ding, Y.C., Rebbeck, T.R., Weitzel, J.N., Lynch, H.T., Isaacs, C., Ganz, P.A., Tomlinson, G., Olopade, O.I., Couch, F.J., Wang, X.S., Lindor, N.M., Pankratz, V.S., Radice, P., Manoukian, S., Peissel, B., Zaffaroni, D., Barile, M., Viel, A., Allavena, A., Dall'Olio, V., Peterlongo, P., Szabo, C.I., Zikan, M., Claes, K., Poppe, B., Foretova, L., Mai, P.L., Greene, M.H., Rennert, G., Lejbkowicz, F., Glendon, G., Ozcelik, H., Andrulis, I.L., Thomassen, M., Gerdes, A.M., Sunde, L., Cruger, D., Jensen, U.B., Caligo, M., Friedman, E., Kaufman, B., Laitman, Y., Milgrom, R., Dubrovsky, M., Cohen, S., Borg, A., Jernstrom, H., Lindblom, A., Rantala, J., Stenmark-Askmalm, M., Melin, B., Nathanson, K., Domchek, S., Jakubowska, A., Lubinski, J., Huzarski, T., Osorio, A., Lasa, A., Duran, M., Tejada, M.I., Godino, J., Benitez, J., Hamann, U., Kriege, M., Hoogerbrugge, N., Luijt, R.B. van der, Asperen, C.J. van, Devilee, P., Meijers-Heijboer, E.J., Blok, M.J., Aalfs, C.M., Hogervorst, F., Rookus, M., Cook, M., Oliver, C., Frost, D., Conroy, D., Evans, D.G., Lalloo, F., Pichert, G., Davidson, R., Cole, T., Cook, J., Paterson, J., Hodgson, S., Morrison, P.J., Porteous, M.E., Walker, L., Kennedy, M.J., Dorkins, H., Peock, S., Godwin, A.K., Stoppa-Lyonnet, D., Pauw, A. de, Mazoyer, S., Bonadona, V., Lasset, C., Dreyfus, H., Leroux, D., Hardouin, A., Berthet, P., Faivre, L., Loustalot, C., Noguchi, T., Sobol, H., Rouleau, E., Nogues, C., Frenay, M., Venat-Bouvet, L., Hopper, J.L., Daly, M.B., Terry, M.B., John, E.M., Buys, S.S., Yassin, Y., Miron, A., Goldgar, D., Singer, C.F., Dressler, A.C., Gschwantler-Kaulich, D., Pfeiler, G., Hansen, T.V.O., Jnson, L., Agnarsson, B.A., Kirchhoff, T., Offit, K., Devlin, V., Dutra-Clarke, A., Piedmonte, M., Rodriguez, G.C., Wakeley, K., Boggess, J.F., Basil, J., Schwartz, P.E., Blank, S.V., Toland, A.E., Montagna, M., Casella, C., Imyanitov, E., Tihomirova, L., Blanco, I., Lazaro, C., Ramus, S.J., Sucheston, L., Karlan, B.Y., Gross, J., Schmutzler, R., Wappenschmidt, B., Engel, C., Meindl, A., Lochmann, M., Arnold, N., Heidemann, S., Varon-Mateeva, R., Niederacher, D., Sutter, C., Deissler, H., Gadzicki, D., Preisler-Adams, S., Kast, K., Schonbuchner, I., Caldes, T., Hoya, M. de la, Aittomaki, K., Nevanlinna, H., Simard, J., Spurdle, A.B., Holland, H., Chen, X.Q., Platte, R., Chenevix-Trench, G., Easton, D.F., Ontario Canc Genetics Network, SWE-BRCA, HEBON, EMBRACE, GEMO, Breast Canc Family Registry, kConFab, CIMBA

Publikováno v: CANCER RESEARCH
r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
instname
Cancer Research, 70, 9742-54
Cancer Research, 70(23), 9742-9754. American Association for Cancer Research Inc.
Cancer Research, 70(23), 9742-9754
Cancer research, 70(23), 9742-9754. American Association for Cancer Research Inc.
Antoniou, A C, Beesley, J, McGuffog, L, Sinilnikova, O M, Healey, S, Neuhausen, S L, Ding, Y C, Rebbeck, T R, Weitzel, J N, Lynch, H T, Isaacs, C, Ganz, P A, Tomlinson, G, Olopade, O I, Couch, F J, Wang, X S, Lindor, N M, Pankratz, V S, Radice, P, Manoukian, S, Peissel, B, Zaffaroni, D, Barile, M, Viel, A, Allavena, A, Dall'Olio, V, Peterlongo, P, Szabo, C I, Zikan, M, Claes, K, Poppe, B, Foretova, L, Mai, P L, Greene, M H, Rennert, G, Lejbkowicz, F, Glendon, G, Ozcelik, H, Andrulis, I L, Thomassen, M, Gerdes, A M, Sunde, L, Cruger, D, Jensen, U B, Caligo, M, Friedman, E, Kaufman, B, Laitman, Y, Milgrom, R, Dubrovsky, M, Cohen, S, Borg, A, Jernstrom, H, Lindblom, A, Rantala, J, Stenmark-Askmalm, M, Melin, B, Nathanson, K L, Domchek, S, Jakubowska, A, Lubinski, J, Huzarski, T, Osorio, A, Lasa, A, Duran, M, Tejada, M I, Godino, J, Benitez, J, Hamann, U, Kriege, M, Hoogerbrugge, N, van der Luijt, R B, van Asperen, C J, Devilee, P, Meijers-Heijboer, E J, Blok, M J, Aalfs, C M, Hogervorst, F, Rookus, M A, Cook, M, Oliver, C, Frost, D, Conroy, D, Evans, D G, Lalloo, F, Pichert, G, Davidson, R, Cole, T, Cook, J, Paterson, J, Hodgson, S, Morrison, P J, Porteous, M E, Walker, L, Kennedy, M J, Dorkins, H, Peock, S, Godwin, A K & Stoppa-Lyonnet, D A O 2010, ' Common Breast Cancer Susceptibility Alleles and the Risk of Breast Cancer for BRCA1 and BRCA2 Mutation Carriers: Implications for Risk Prediction ', Cancer Research, vol. 70, no. 23, pp. 9742-9754 . https://doi.org/10.1158/0008-5472.CAN-10-1907
Antoniou, A C, Beesley, J, McGuffog, L, Sinilnikova, O M, Healey, S, Neuhausen, S L, Ding, Y C, Rebbeck, T R, Weitzel, J N, Lynch, H T, Isaacs, C, Ganz, P A, Tomlinson, G, Olopade, O I, Couch, F J, Wang, X, Lindor, N M, Pankratz, V S, Radice, P, Manoukian, S, Peissel, B, Zaffaroni, D, Barile, M, Viel, A, Allavena, A, Dall'olio, V, Peterlongo, P, Szabo, C I, Zikan, M, Claes, K, Poppe, B, Foretova, L, Mai, P L, Greene, M H, Rennert, G, Lejbkowicz, F, Glendon, G, Ozcelik, H, Andrulis, I L, for the Ontario Cancer Genetics Network, Thomassen, M, Gerdes, A-M, Sunde, L, Cruger, D, Birk Jensen, U, Caligo, M, Friedman, E, Kaufman, B, Laitman, Y, Milgrom, R, Dubrovsky, M, for SWE-BRCA, for HEBON, for EMBRACE, for GEMO, for GEMO, for the Breast Cancer Family Registry, for kConFab & on behalf of CIMBA 2010, ' Common Breast Cancer Susceptibility Alleles and the Risk of Breast Cancer for BRCA1 and BRCA2 Mutation Carriers: Implications for Risk Prediction ', Cancer Research, vol. 70, no. 23, pp. 9742-9754 . https://doi.org/10.1158/0008-5472.CAN-10-1907
Cancer Research, 70, 23, pp. 9742-54
Antoniou, A C, Beesley, J, McGuffog, L, Sinilnikova, O M, Healey, S, Neuhausen, S L, Ding, Y C, Rebbeck, T R, Weitzel, J N, Lynch, H T, Isaacs, C, Ganz, P A, Tomlinson, G, Olopade, O I, Couch, F J, Wang, X, Lindor, N M, Pankratz, V S, Radice, P, Manoukian, S, Peissel, B, Zaffaroni, D, Barile, M, Viel, A, Allavena, A, Dall'Olio, V, Peterlongo, P, Szabo, C I, Zikan, M, Claes, K, Poppe, B, Foretova, L, Mai, P L, Greene, M H, Rennert, G, Lejbkowicz, F, Glendon, G, Ozcelik, H, Andrulis, I L, Thomassen, M, Gerdes, A-M A, Sunde, L E M, Cruger, D, Jensen, U B, Caligo, M, Friedman, E, Kaufman, B, Laitman, Y, Milgrom, R, Dubrovsky, M & Ontario Cancer Genetics Network 2010, ' Common breast cancer susceptibility alleles and the risk of breast cancer for BRCA1 and BRCA2 mutation carriers: implications for risk prediction ', Cancer Research Institute Report, vol. 70, no. 23, pp. 9742-54 . https://doi.org/10.1158/0008-5472.CAN-10-1907

The known breast cancer susceptibility polymorphisms in FGFR2, TNRC9/TOX3, MAP3K1, LSP1, and 2q35 confer increased risks of breast cancer for BRCA1 or BRCA2 mutation carriers. We evaluated the associations of 3 additional single nucleotide polymorphi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d96fa390c9aac813f393d9cdfa58a343
https://iibsantpau.fundanetsuite.com/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=12416

Common variants in LSP1, 2q35 and 8q24 and breast cancer risk for BRCA1 and BRCA2 mutation carriers

Autor: Antoniou, AC, Sinilnikova, OM, McGuffog, L, Healey, S, Nevanlinna, H, Heikkinen, T, Simard, J, Spurdle, AB, Beesley, J, Chen, XQ, Neuhausen, SL, Ding, YC, Couch, FJ, Wang, XS, Fredericksen, Z, Peterlongo, P, Peissel, B, Bonanni, B, Viel, A, Bernard, L, Radice, P, Szabo, CI, Foretova, L, Zikan, M, Claes, K, Greene, MH, Mai, PL, Rennert, G, Lejbkowicz, F, Andrulis, IL, Ozcelik, H, Glendon, G, Gerdes, AM, Thomassen, M, Sunde, L, Caligo, MA, Laitman, Y, Kontorovich, T, Cohen, S, Kaufman, B, Dagan, E, Baruch, RG, Friedman, E, Harbst, K, Barbany-Bustinza, G, Rantala, J, Ehrencrona, H, Karlsson, P, Domchek, SM, Nathanson, KL, Osorio, A, Blanco, I, Lasa, A, Benitez, J, Hamann, U, Hogervorst, FBL, Rookus, MA, Collee, JM, Devilee, P, Ligtenberg, MJ, van der Luijt, RB, Aalfs, CM, Waisfisz, Q, Wijnen, J, van Roozendaal, CEP, Peock, S, Cook, M, Frost, D, Oliver, C, Platte, R, Evans, DG, Lalloo, F, Eeles, R, Izatt, L, Davidson, R, Chu, C, Eccles, D, Cole, T, Hodgson, S, Godwin, AK, Stoppa-Lyonnet, D, Buecher, B, Leone, M, Bressac-de Paillerets, B, Remenieras, A, Caron, O, Lenoir, GM, Sevenet, N, Longy, M, Ferrer, SF, Prieur, F, Goldgar, D, Miron, A, John, EM, Buys, SS, Daly, MB, Hopper, JL, Terry, MB, Yassin, Y, Singer, C, Gschwantler-Kaulich, D, Staudigl, C, Hansen, TVO, Barkardottir, RB, Kirchhoff, T, Pal, P, Kosarin, K, Offit, K, Piedmonte, M, Rodriguez, GC, Wakeley, K, Boggess, JF, Basil, J, Schwartz, PE, Blank, SV, Toland, AE, Montagna, M, Casella, C, Imyanitov, EN, Allavena, A, Schmutzler, RK, Versmold, B, Engel, C, Meindl, A, Ditsch, N, Arnold, N, Niederacher, D, Deissler, H, Fiebig, B, Suttner, C, Schonbuchner, I, Gadzicki, D, Caldes, T, de la Hoya, M, Pooley, KA, Easton, DF, Chenevix-Trench, G

Publikováno v: HUMAN MOLECULAR GENETICS
r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
instname

Genome-wide association studies of breast cancer have identified multiple single nucleotide polymorphisms (SNPs) that are associated with increased breast cancer risks in the general population. In a previous study, we demonstrated that the minor all

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=RECOLECTA___::719017cd34ce7939b9aa66f7dd0d74f3
https://iibsantpau.fundanetsuite.com/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=12952

Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.

Current trends in the management of carcinoma of the cervix, vulva, and vagina.

Autor: Brooks, S E, Wakeley, K E

Publikováno v: Current Opinion in Oncology; 1999 Sep, Vol. 11 Issue 5, p383-387, 5p