Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Wakana Kobayashi"'
Publikováno v:
Journal of Physical Fitness and Sports Medicine, Vol 11, Iss 1, Pp 21-28 (2022)
In order to clarify the acute effects of exercise on the cold sensory function of cold-sensitive women, 12 young adult females with an awareness of cold constitution were subjected to two experiments: an exercise condition in which cycle exercise wit
Externí odkaz:
https://doaj.org/article/f83afbe9446c4492a940339d80bd1e5a
Autor:
Hideki Ueno, Seiko Narushima, Alexis Vogelzang, Yuki Sugiura, Katsuyuki Shiroguchi, Kenji Chamoto, Michio Miyajima, Wakana Kobayashi, Taisaku Ogawa, Yumi Tsutsui, Keiichiro Suzuki, Sachiko Yamamoto, Baihao Zhang, Ryusuke Hatae, Sidonia Fagarasan, Katsuhiro Ito, Makoto Suematsu, Motomu Hashimoto, Rosemary J. Menzies, Mikako Maruya, Takashi Kobayashi, Kazuhiro Sonomura, Kosaku Murakami, Nozomi Hojo, Tomoko Hirano, Fumihiko Matsuda, Yibo Wu, Tasuku Honjo, Rei Nakano, Hiroshi Sugiya
Publikováno v:
Nature. 599(7885):471-476
Small, soluble metabolites not only are essential intermediates in intracellular biochemical processes, but can also influence neighbouring cells when released into the extracellular milieu1-3. Here we identify the metabolite and neurotransmitter GAB
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a82a7c5fe0437799ea50cd18b3ad07f
http://hdl.handle.net/2433/266090
http://hdl.handle.net/2433/266090
Autor:
Baihao, Zhang, Alexis, Vogelzang, Michio, Miyajima, Yuki, Sugiura, Yibo, Wu, Kenji, Chamoto, Rei, Nakano, Ryusuke, Hatae, Rosemary J, Menzies, Kazuhiro, Sonomura, Nozomi, Hojo, Taisaku, Ogawa, Wakana, Kobayashi, Yumi, Tsutsui, Sachiko, Yamamoto, Mikako, Maruya, Seiko, Narushima, Keiichiro, Suzuki, Hiroshi, Sugiya, Kosaku, Murakami, Motomu, Hashimoto, Hideki, Ueno, Takashi, Kobayashi, Katsuhiro, Ito, Tomoko, Hirano, Katsuyuki, Shiroguchi, Fumihiko, Matsuda, Makoto, Suematsu, Tasuku, Honjo, Sidonia, Fagarasan
Publikováno v:
Nature
Small, soluble metabolites not only are essential intermediates in intracellular biochemical processes, but can also influence neighbouring cells when released into the extracellular milieu1–3. Here we identify the metabolite and neurotransmitter G
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cea73965f469f4f3bbe2337dc5bc086e
https://pubmed.ncbi.nlm.nih.gov/34732892
https://pubmed.ncbi.nlm.nih.gov/34732892
Autor:
Fusako Kusunoki, Etsuji Yamaguchi, Yoshiaki Takeda, Wakana Kobayashi, Yukiya Shingai, Hiroshi Mizoguchi, Hideo Funaoi, Masanori Sugimoto, Ryota Aoki, Shigenori Inagaki, Koga Yago
Publikováno v:
CSEDU (1)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5e94df254201b2b7d6360ce13fea96e5
https://doi.org/10.5220/0010473703470351
https://doi.org/10.5220/0010473703470351
Autor:
Takayuki Imanishi, Shizuo Akira, Midori Unno, Wakana Kobayashi, Natsumi Yoneda, Takashi Saito
Publikováno v:
Cell reports. 32(3)
Summary Effector, but not naive, T cells are activated by toll-like receptor-2 (TLR2) stimulation, leading to cytokine production and proliferation. We found that the differential response is attributable to the lack of expression of the adaptor prot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::101be513e18eec2d9ec1135131ab276b
https://pubmed.ncbi.nlm.nih.gov/32698010
https://pubmed.ncbi.nlm.nih.gov/32698010
Autor:
Makoto Arita, Natsumi Yoneda, Midori Unno, Glen N. Barber, Kazutaka Ikeda, Satoshi Matsuda, Takayuki Imanishi, Takayuki Hoshii, Shizuo Akira, Takashi Saito, Ken Ishii, Kensuke Miyake, Atsushi Hirao, Wakana Kobayashi
Publikováno v:
Life Science Alliance
Costimulation of T cells through both TCR and STING induces growth inhibition by partially blocking the mTORC1 signals, and leads to IFN-I production through sustained activation of IRF3 and mTORC1 activation.
Stimulator of interferon genes (STI
Stimulator of interferon genes (STI
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a67223c17183483a2beda8a5f88f35fd
https://doi.org/10.26508/lsa.201800282
https://doi.org/10.26508/lsa.201800282
Autor:
Masako Takamatsu, Miyuki Azuma, Tadashi Yokosuka, Akiko Hashimoto-Tane, Takashi Saito, Wakana Kobayashi-Imanishi
Publikováno v:
The Journal of Experimental Medicine
After encounter with its ligand, PD-1 translocates into TCR microclusters, where it transiently recruits SHP2 and suppresses phosphorylation of TCR signaling components and TCR-driven stop signals.
Programmed cell death 1 (PD-1) is a negative co
Programmed cell death 1 (PD-1) is a negative co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f7fa08a69c0d475e0bec43def8733e7
https://doi.org/10.1084/jem.20112741
https://doi.org/10.1084/jem.20112741
Autor:
Kumiko Sakata-Sogawa, Akiko Hashimoto-Tane, Michael L. Dustin, Michio Hiroshima, Tadashi Yokosuka, Makio Tokunaga, Wakana Kobayashi, Takashi Saito
Publikováno v:
nature immunology. 6(number 12):1253-1262
T cell receptor (TCR) activation and signaling precede immunological synapse formation and are sustained for hours after initiation. However, the precise physical sites of the initial and sustained TCR signaling are not definitively known. We report
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f35f6b94ff24a3567a94b9a4928289f9
http://t2r2.star.titech.ac.jp/cgi-bin/publicationinfo.cgi?q_publication_content_number=CTT100592724
http://t2r2.star.titech.ac.jp/cgi-bin/publicationinfo.cgi?q_publication_content_number=CTT100592724
Autor:
Chitose Ishihara, Machie Sakuma, Takashi Saito, Wakana Kobayashi, Tadashi Yokosuka, Akiko Hashimoto-Tane
Publikováno v:
Molecular and cellular biology. 30(14)
We studied the function of lipid rafts in generation and signaling of T-cell receptor microclusters (TCR-MCs) and central supramolecular activation clusters (cSMACs) at immunological synapse (IS). It has been suggested that lipid raft accumulation cr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::977d88944e2c81ccd6a8c271ccd394de
https://pubmed.ncbi.nlm.nih.gov/20498282
https://pubmed.ncbi.nlm.nih.gov/20498282
Autor:
Tadashi Yokosuka, Makio Tokunaga, Takashi Saito, Masako Takamatsu, Kumiko Sakata-Sogawa, Akiko Hashimoto-Tane, Hu Zeng, Hideo Yagita, Wakana Kobayashi
Publikováno v:
Immunity. 33(3)
SummaryT cell activation is positively and negatively regulated by a pair of costimulatory receptors, CD28 and CTLA-4, respectively. Because these receptors share common ligands, CD80 and CD86, the expression and behavior of CTLA-4 is critical for T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc529480fbbb64224e31e502b190ba43
https://pubmed.ncbi.nlm.nih.gov/20870175
https://pubmed.ncbi.nlm.nih.gov/20870175