Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Wakako Suhara"'
Autor:
Kiyoshi Aita, Dobun Hayashi, Hideyuki Koide, Kenichi Sato, Hitoshi Kojo, Tsugumi Okuzawa, Tetsuro Nakamura, Wakako Suhara, Satoru Nakano
Publikováno v:
Journal of Food Biochemistry. 35:776-791
A saponin-enriched soybean extract was tested for agonistic activities against a series of nuclear receptors including peroxisome proliferator-activated receptors (PPARs) and cholesterol metabolism-related, retinoid-related, hormone-related and detox
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::84b5e433d6f227a9fa2e0bd0e8a6614d
https://doi.org/10.1111/j.1745-4514.2010.00416.x
https://doi.org/10.1111/j.1745-4514.2010.00416.x
Autor:
Masanobu Kobayashi, Kiyoshi Aita, Stephanie Darmanin, Takeshi Kondo, Futoshi Okada, Hideyuki Koide, Masahiro Asaka, Mariko Ozasa, Fumihiro Higashino, Mitsuteru Natsuizaka, Suguru Kamada, Masanobu Shindoh, Koji Nakagawa, Satoshi Kondo, Masaki Miyamoto, Wakako Suhara
Publikováno v:
Experimental Cell Research. 313(15):3337-3348
There is accumulating evidence demonstrating that HIF-1 functions as a key regulator of the adaptation responses to hypoxia in cancer tissues. To this evidence, we add that adaptation responses to glucose deprivation plus hypoxia are also necessary f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::418f1984a8786cd213ee203cc6aa3e62
http://hdl.handle.net/2115/29921
http://hdl.handle.net/2115/29921
Autor:
Ichiro Fujimoto, Wakako Suhara, Katsuhiko Mikoshiba, Kozo Hamada, Touichiro Goto, Keiichi Torimitsu, Hiroshi Sagara, Mime Kobayashi
Publikováno v:
Neuroscience Letters. 391:102-107
Inositol 1,4,5-trisphosphate (IP(3)) receptor (IP(3)R) acts as a ligand-gated channel that mediates neuronal signals by releasing Ca(2+) from the endoplasmic reticulum. The three-dimensional (3D) structure of tetrameric IP(3)R has been demonstrated b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d18c6c7122c1dfadd8d7a2714e035272
https://doi.org/10.1016/j.neulet.2005.08.066
https://doi.org/10.1016/j.neulet.2005.08.066
Autor:
Yasutaka Okabe, Shizuo Akira, Fuyuhiko Inagaki, Kiyohiro Takahasi, Yukiko Fukuhara, Masataka Horiuchi, Wakako Suhara, Mitsuaki Mori, Nobuo Suzuki, Hiroaki Terasawa, Takashi Fujita
Publikováno v:
Nature Structural & Molecular Biology. 10:922-927
Transcription factor IRF-3 is post-translationally activated by Toll-like receptor (TLR) signaling and has critical roles in the regulation of innate immunity. Here we present the X-ray crystal structure of the C-terminal regulatory domain of IRF-3(1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1c641fb04f4485681d187acf5add9a0a
https://doi.org/10.1038/nsb1001
https://doi.org/10.1038/nsb1001
Autor:
Fumio Amano, Mitsutoshi Yoneyama, Takashi Fujita, Tomokatsu Iwamura, Kazumi Yamaguchi, Yukiko Fukuhara, Noriaki Shinobu, Wakako Suhara
Publikováno v:
FEBS Letters. 517:251-256
Infections of bacteria and viruses induce host defense reactions known as innate responses that include the production of cytokines and chemokines. The production of type I interferon (IFN) is known to be induced by viral double-stranded (ds) RNA or
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d4547bd70ecd8bb5557890e139047c9
https://doi.org/10.1016/s0014-5793(02)02636-4
https://doi.org/10.1016/s0014-5793(02)02636-4
Autor:
Wakako Suhara, Wakana Mori, Takashi Fujita, Yasutaka Okabe, Kazumi Yamaguchi, Kazutaka Shiota, Hideo Namiki, Mitsutoshi Yoneyama, Tomokatsu Iwamura
Publikováno v:
Genes to Cells. 6:375-388
Background Infection by virus or treatment with double-stranded RNA (dsRNA) results in the activation of transcription factors including IRF-3, IRF-7 and a pleiotropic regulator NF-kappaB by specific phosphorylation. These factors are important in tr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f146a16e2d6909f67de026858bc826e4
https://doi.org/10.1046/j.1365-2443.2001.00426.x
https://doi.org/10.1046/j.1365-2443.2001.00426.x
Publikováno v:
Journal of Biochemistry. 119:231-234
Interferon stimulated gene factor 3 (ISGF3) is a trimeric transcription factor activated on treatment of cells with interferon-alpha and beta (type I IFNs). Upon stimulation, the regulatory subunits, p84/91 and p113, present in the cytoplasm are phos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aed20a7e178c92d79b9493a2a32c67cc
https://doi.org/10.1093/oxfordjournals.jbchem.a021227
https://doi.org/10.1093/oxfordjournals.jbchem.a021227
Publikováno v:
The Journal of biological chemistry. 277(25)
Infections of bacteria and viruses induce host defense reactions known as innate responses including the activation of interferon regulatory factor-3 (IRF-3), critical for the activation of type I interferon system. Upon immediate early signals trigg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7eed075ec9259f2f0be1349ea8c279be
https://pubmed.ncbi.nlm.nih.gov/11940575
https://pubmed.ncbi.nlm.nih.gov/11940575
Publikováno v:
Journal of interferoncytokine research : the official journal of the International Society for Interferon and Cytokine Research. 22(1)
Interferon (IFN) regulatory factor-3 (IRF-3) is a unique member of the IRF family. Its transcriptional activity is regulated solely by posttranslational modifications. We review current knowledge of the mechanism of IRF-3 activation: signalling trigg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::840168fbd330d7bee1a715482b3447e0
https://pubmed.ncbi.nlm.nih.gov/11846977
https://pubmed.ncbi.nlm.nih.gov/11846977
Autor:
Keiko Tamura, Hideo Namiki, Saburo Aimoto, Shoko Yoshimura, Tomokatsu Iwamura, Mitsutoshi Yoneyama, Wakako Suhara, Takashi Fujita
Publikováno v:
ResearcherID
Cellular genes including the type I interferon genes are activated in response to viral infection. We previously reported that IRF-3 (interferon regulatory factor 3) is specifically phosphorylated on serine residues and directly transmits a virus-ind
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29fafc7928f6045c6804d7c177537676
https://pubmed.ncbi.nlm.nih.gov/10920266
https://pubmed.ncbi.nlm.nih.gov/10920266