Systematic analysis of the Candida albicans kinome reveals environmentally contingent protein kinase-mediated regulation of filamentation and biofilm formation in vitro and in vivo .

Autor: Kramara J; Department of Pediatrics, Carver College of Medicine, University of Iowa, Iowa City, Iowa, USA., Kim M-J; Department of Microbiology, University of Georgia, Athens, Georgia, USA., Ollinger TL; Department of Pediatrics, Carver College of Medicine, University of Iowa, Iowa City, Iowa, USA., Ristow LC; Department of Pediatrics, Carver College of Medicine, University of Iowa, Iowa City, Iowa, USA., Wakade RS; Department of Pediatrics, Carver College of Medicine, University of Iowa, Iowa City, Iowa, USA., Zarnowski R; Department of Medicine, Section of Infectious Disease, University of Wisconsin, Madison, Wisconsin, USA.; Department of Medical Microbiology and Immunology, University of Wisconsin, Madison, Wisconsin, USA., Wellington M; Department of Pediatrics, Carver College of Medicine, University of Iowa, Iowa City, Iowa, USA., Andes DR; Department of Medicine, Section of Infectious Disease, University of Wisconsin, Madison, Wisconsin, USA.; Department of Medical Microbiology and Immunology, University of Wisconsin, Madison, Wisconsin, USA., Mitchell AG; Department of Microbiology, University of Georgia, Athens, Georgia, USA., Krysan DJ; Department of Pediatrics, Carver College of Medicine, University of Iowa, Iowa City, Iowa, USA.; Department of Molecular Physiology and Biophysics, Carver College of Medicine, University of Iowa, Iowa City, Iowa, USA.

Publikováno v: MBio [mBio] 2024 Aug 14; Vol. 15 (8), pp. e0124924. Date of Electronic Publication: 2024 Jul 01.

The role of the C. albicans transcriptional repressor NRG1 during filamentation and disseminated candidiasis is strain dependent.

Autor: Wakade RS; Department of Pediatrics, Carver College of Medicine, University of Iowa, Iowa City, Iowa, USA., Wellington M; Department of Pediatrics, Carver College of Medicine, University of Iowa, Iowa City, Iowa, USA., Krysan DJ; Department of Pediatrics, Carver College of Medicine, University of Iowa, Iowa City, Iowa, USA.; Department of Molecular Physiology and Biophysics, Carver College of Medicine, University of Iowa, Iowa City, Iowa, USA.

Publikováno v: MSphere [mSphere] 2024 Mar 26; Vol. 9 (3), pp. e0078523. Date of Electronic Publication: 2024 Feb 20.

The Candida albicans reference strain SC5314 contains a rare, dominant allele of the transcription factor Rob1 that modulates filamentation, biofilm formation, and oral commensalism.

Autor: Glazier VE; Department of Biology, Niagara University , Niagara Falls, New York, USA., Kramara J; Department of Pediatrics, Carver College of Medicine, University of Iowa , Iowa City, Iowa, USA., Ollinger T; Department of Pediatrics, Carver College of Medicine, University of Iowa , Iowa City, Iowa, USA., Solis NV; Division of Infectious Diseases, Los Angeles Biomedical Research Institute and Harbor-UCLA Medical Center , Torrance, California, USA.; Department of Medicine, David Geffen School of Medicine at UCLA , Los Angeles, California, USA., Zarnowski R; Department of Medicine, Section of Infectious Disease, University of Wisconsin , Madison, Wisconsin, USA.; Department of Medical Microbiology and Immunology, University of Wisconsin , Madison, Wisconsin, USA., Wakade RS; Department of Pediatrics, Carver College of Medicine, University of Iowa , Iowa City, Iowa, USA., Kim M-J; Department of Microbiology, University of Georgia , Athens, Georgia, USA., Weigel GJ; Department of Pediatrics, Carver College of Medicine, University of Iowa , Iowa City, Iowa, USA., Liang S-H; Department of Molecular Microbiology and Immunology, Brown University , Providence, Rhode Island, USA., Bennett RJ; Department of Molecular Microbiology and Immunology, Brown University , Providence, Rhode Island, USA., Wellington M; Department of Pediatrics, Carver College of Medicine, University of Iowa , Iowa City, Iowa, USA., Andes DR; Department of Medicine, Section of Infectious Disease, University of Wisconsin , Madison, Wisconsin, USA.; Department of Medical Microbiology and Immunology, University of Wisconsin , Madison, Wisconsin, USA., Stamnes MA; Department of Molecular Physiology and Biophysics, Carver College of Medicine, University of Iowa , Iowa City, Iowa, USA., Filler SG; Division of Infectious Diseases, Los Angeles Biomedical Research Institute and Harbor-UCLA Medical Center , Torrance, California, USA.; Department of Medicine, David Geffen School of Medicine at UCLA , Los Angeles, California, USA., Krysan DJ; Department of Pediatrics, Carver College of Medicine, University of Iowa , Iowa City, Iowa, USA.; Department of Molecular Physiology and Biophysics, Carver College of Medicine, University of Iowa , Iowa City, Iowa, USA.; Department of Microbiology and Immunology, Carver College of Medicine, University of Iowa , Iowa City, Iowa, USA.

Publikováno v: MBio [mBio] 2023 Oct 31; Vol. 14 (5), pp. e0152123. Date of Electronic Publication: 2023 Sep 22.

The Candida albicans reference strain SC5314 contains a rare, dominant allele of the transcription factor Rob1 that modulates biofilm formation and oral commensalism.

Autor: Glazier VE; Department of Biology, Niagara University, Niagara Falls NY., Kramara J; Department of Pediatrics, Carver College of Medicine, University of Iowa, Iowa City IA., Ollinger T; Department of Pediatrics, Carver College of Medicine, University of Iowa, Iowa City IA., Solis NV; Division of Infectious Diseases, Los Angeles Biomedical Research Institute and Harbor-UCLA Medical Center, Torrance, CA.; Department of Medicine, David Geffen School of Medicine at UCLA, Los Angeles, CA., Zarnowski R; Department of Medicine, Section of Infectious Disease, University of Wisconsin, Madison WI.; Department of Medical Microbiology and Immunology, University of Wisconsin, Madison WI., Wakade RS; Department of Pediatrics, Carver College of Medicine, University of Iowa, Iowa City IA., Kim MJ; Department of Microbiology, University of Georgia, Athens, GA., Weigel GJ; Department of Pediatrics, Carver College of Medicine, University of Iowa, Iowa City IA., Liang SH; Department of Molecular Microbiology and Immunology, Brown University, Providence, RI., Bennett RJ; Department of Molecular Microbiology and Immunology, Brown University, Providence, RI., Wellington M; Department of Pediatrics, Carver College of Medicine, University of Iowa, Iowa City IA., Andes DR; Department of Medicine, Section of Infectious Disease, University of Wisconsin, Madison WI.; Department of Medical Microbiology and Immunology, University of Wisconsin, Madison WI., Stamnes MA; Department of Molecular Physiology and Biophysics, Carver College of Medicine, University of Iowa, Iowa City, IA., Filler SG; Division of Infectious Diseases, Los Angeles Biomedical Research Institute and Harbor-UCLA Medical Center, Torrance, CA.; Department of Medicine, David Geffen School of Medicine at UCLA, Los Angeles, CA., Krysan DJ; Department of Pediatrics, Carver College of Medicine, University of Iowa, Iowa City IA.; Department of Molecular Physiology and Biophysics, Carver College of Medicine, University of Iowa, Iowa City, IA.; Department of Microbiology and Immunology, Carver College of Medicine, University of Iowa, Iowa City IA.

Publikováno v: BioRxiv : the preprint server for biology [bioRxiv] 2023 Jun 17. Date of Electronic Publication: 2023 Jun 17.

Human Tooth as a Fungal Niche: Candida albicans Traits in Dental Plaque Isolates.

Autor: Xiang Z; Biofilm Research Laboratories, Department of Orthodontics, Divisions of Community Oral Health & Pediatric Dentistry, School of Dental Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.; State Key Laboratory of Oral Diseases and National Clinical Research Center for Oral Diseases, Department of Cariology and Endodontics, West China Hospital of Stomatology, Sichuan University, Chengdu, China., Wakade RS; Department of Pediatrics, Carver College of Medicine, University of Iowa, Iowa City, Iowa, USA., Ribeiro AA; Division of Diagnostic Sciences, Adams School of Dentistry, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA., Hu W; Division of Gastroenterology, Hepatology, and Nutrition, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA., Bittinger K; Division of Gastroenterology, Hepatology, and Nutrition, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA., Simon-Soro A; Biofilm Research Laboratories, Department of Orthodontics, Divisions of Community Oral Health & Pediatric Dentistry, School of Dental Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.; Department of Stomatology, School of Dentistry, University of Seville, Seville, Spain., Kim D; Department of Preventive Dentistry, School of Dentistry, Jeonbuk National University, Jeonju, South Korea., Li J; State Key Laboratory of Oral Diseases and National Clinical Research Center for Oral Diseases, Department of Cariology and Endodontics, West China Hospital of Stomatology, Sichuan University, Chengdu, China., Krysan DJ; Department of Pediatrics, Carver College of Medicine, University of Iowa, Iowa City, Iowa, USA.; Department of Microbiology and Immunology, Carver College of Medicine, University of Iowa, Iowa City, Iowa, USA., Liu Y; Biofilm Research Laboratories, Department of Orthodontics, Divisions of Community Oral Health & Pediatric Dentistry, School of Dental Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.; Department of Preventive & Restorative Sciences, School of Dental Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA., Koo H; Biofilm Research Laboratories, Department of Orthodontics, Divisions of Community Oral Health & Pediatric Dentistry, School of Dental Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.; Center for Innovation & Precision Dentistry, School of Dental Medicine and School of Engineering & Applied Sciences, University of Pennsylvania, Philadelphia, Pennsylvania, USA.

Publikováno v: MBio [mBio] 2023 Feb 28; Vol. 14 (1), pp. e0276922. Date of Electronic Publication: 2023 Jan 05.