Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Waitman K. Aumann"'
Publikováno v:
Oncology Reviews, Vol 18 (2024)
Chromosome Region Maintenance 1 (CRM1), also known as Exportin 1 (XPO1), is a protein that is critical for transport of proteins and RNA to the cytoplasm through the nuclear pore complex. CRM1 inhibition with small molecule inhibitors is currently be
Externí odkaz:
https://doaj.org/article/e5bc8c6adb384b8b8cc22dcfd2c8e2cc
Autor:
Catherine P Lavau, Waitman K Aumann, Sei-Gyung K Sze, Veerain Gupta, Katelyn Ripple, Sarah A Port, Ralph H Kehlenbach, Daniel S Wechsler
Publikováno v:
PLoS ONE, Vol 15, Iss 4, p e0232036 (2020)
The NUP98 and NUP214 nucleoporins (NUPs) are recurrently fused to heterologous proteins in leukemia. The resulting chimeric oncoproteins retain the phenylalanine-glycine (FG) repeat motifs of the NUP moiety that mediate interaction with the nuclear e
Externí odkaz:
https://doaj.org/article/e20feed315bf4dd9b9465d7ea188da83
Autor:
Diana M. Fridlyand, Shanmuganathan Chandrakasan, Ahmed Aljudi, Waitman K. Aumann, Eleanor Westfall, Bailey Kirwan, Elyse W. Bryson, Frank G. Keller, Staci D. Arnold, Andrew L. Hong, Melinda Pauly, Kirsten M. Williams
Publikováno v:
Journal of Pediatric Hematology/Oncology. 45:e139-e141
Patients with DNA double-strand breakage repair disorders are at increased risk of malignancy which is often difficult to treat given underlying sensitivity to chemotherapy and radiotherapy, lending an important role to hematopoietic stem cell transp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::372a9c0002d920818f31084f19b3564d
https://doi.org/10.1097/mph.0000000000002489
https://doi.org/10.1097/mph.0000000000002489
Publikováno v:
Blood. 138:3312-3312
Background: Leukemia is the most common type of childhood cancer. Although the prognosis for many pediatric leukemias has improved, leukemias associated with the t(10;11) CALM-AF10 translocation remain difficult to treat. CALM-AF10 leukemias account
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7922db327802da244a07c3fa6eb79d69
https://doi.org/10.1182/blood-2021-152644
https://doi.org/10.1182/blood-2021-152644
Autor:
Waitman K. Aumann, Dongdong Julie Chen, Amanda E. Conway, Daniel S. Wechsler, Catherine Lavau, Heide L. Ford
Publikováno v:
Blood. 138:4331-4331
Background : The CALM-AF10 translocation is found in 5-10% of T-cell acute lymphoblastic leukemias (T-ALL), and a subset of acute myeloid leukemias (AML). CALM-AF10 leukemias are characterized by elevated expression of proleukemic HOXA genes. Since H
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::281af381fa857ac6f5b3f9c09b0ba97c
https://doi.org/10.1182/blood-2021-154156
https://doi.org/10.1182/blood-2021-154156
Autor:
Hengbo Zhou, Catherine Lavau, Heide L. Ford, Amanda Harrington, Waitman K. Aumann, Amanda E. Conway, Donald Tope, Daniel S. Wechsler
Publikováno v:
Blood. 136:38-39
Background : The CALM-AF10 translocation is found 5-10% of T-cell acute lymphoblastic leukemias (T-ALL), and a subset of acute myeloid leukemias (AML). CALM-AF10 leukemias are characterized by elevated expression of proleukemic HOXA genes. Since HOXA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6ec91c7ab7e7ccd31cb4955d4365bcdb
https://doi.org/10.1182/blood-2020-140754
https://doi.org/10.1182/blood-2020-140754
Publikováno v:
Blood. 136:14-14
Background: Leukemia is the most common type of childhood cancer. Although the prognosis for many pediatric leukemias has improved, leukemias associated with the t(10;11) CALM-AF10 translocation remain difficult to treat. CALM-AF10 leukemias account
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bfca3a97e27cd6292493b7575df0694c
https://doi.org/10.1182/blood-2020-138816
https://doi.org/10.1182/blood-2020-138816
Autor:
Sei-Gyung K. Sze, Catherine Lavau, Sarah A. Port, Ralph H. Kehlenbach, Waitman K. Aumann, Veerain Gupta, Daniel S. Wechsler, Katelyn Ripple
Publikováno v:
PLoS ONE
PLoS ONE, Vol 15, Iss 4, p e0232036 (2020)
PLoS ONE, Vol 15, Iss 4, p e0232036 (2020)
The NUP98 and NUP214 nucleoporins (NUPs) are recurrently fused to heterologous proteins in leukemia. The resulting chimeric oncoproteins retain the phenylalanine-glycine (FG) repeat motifs of the NUP moiety that mediate interaction with the nuclear e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e8aa6b22865b99e13ad03bd5d63c6c8
https://doi.org/10.1371/journal.pone.0232036
https://doi.org/10.1371/journal.pone.0232036
Publikováno v:
Journal of pediatric hematology/oncology. 40(7)
Central nervous system (CNS) chloromas are an exceedingly rare presentation of CNS relapse in acute lymphoblastic leukemia (ALL). We report a relapsed ALL patient who presented with 2 separate chloromas and cerebrospinal fluid lymphoblastocytosis, an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fde916222848e4eedc3a0240861a32ba
https://pubmed.ncbi.nlm.nih.gov/29334537
https://pubmed.ncbi.nlm.nih.gov/29334537
Autor:
Waitman K. Aumann, Catherine Lavau, Sei-Gyung K. Sze, Ralph H. Kehlenbach, Veerain Gupta, Sarah A. Port, Daniel S. Wechsler, Katelyn Ripple
Publikováno v:
Blood. 134:1434-1434
Background: The NUP98 and NUP214 nucleoporins (NUPs) are recurrently fused to heterologous proteins in leukemia. The resulting chimeric oncoproteins retain the NUP phenylalanine-glycine (FG) repeat motifs that mediate interaction with the nuclear exp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9b463e14f5e3cdd5e86f7447ff97b54f
https://doi.org/10.1182/blood-2019-130530
https://doi.org/10.1182/blood-2019-130530