Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Wai-chi Ho"'
Autor:
Wai, Chi Ho1,2 (AUTHOR), Jin, Jessica1,2 (AUTHOR), Cyrklaff, Marek2 (AUTHOR), Genoud, Christel3 (AUTHOR), Funaya, Charlotta4 (AUTHOR), Sattler, Julia2 (AUTHOR), Maceski, Aleksandra5 (AUTHOR), Meier, Stephanie5 (AUTHOR), Heiland, Sabine1 (AUTHOR), Lanzer, Michael2 (AUTHOR), Frischknecht, Friedrich2,6 (AUTHOR), Kuhle, Jens5 (AUTHOR), Bendszus, Martin1 (AUTHOR), Hoffmann, Angelika1,7 (AUTHOR) angelika.hoffmann@insel.ch
Publikováno v:
Scientific Reports. 6/24/2022, Vol. 12 Issue 1, p1-11. 11p.
Akademický článek
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Publikováno v:
Journal of Biological Chemistry. 287:15458-15465
We investigated the role of the ubiquitously expressed calpain 2 isoform in breast tumor cell growth, migration, signaling, and tumorigenesis. RNAi-mediated knockdown of the capn2 transcript was used to manipulate expression of the catalytic subunit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::725dffe55670e0f43cd5062386906a9c
https://doi.org/10.1074/jbc.m112.349308
https://doi.org/10.1074/jbc.m112.349308
Autor:
Wai Chi Ho, Alain Boudreault, Snezana Milutinovic, Kathleen M. Dickson, Philip A. Barker, John W. Gillard, James B. Jaquith, Stephen Morris, Jon P. Durkin, Mathieu J.M. Bertrand
Publikováno v:
Molecular Cell. 30(6):689-700
Summary The inhibitor of apoptosis (IAP) family of proteins enhances cell survival through mechanisms that remain uncertain. In this report, we show that cIAP1 and cIAP2 promote cancer cell survival by functioning as E3 ubiquitin ligases that maintai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::050a907688fb9867737ade2b5e741f01
Autor:
Amir H. Salehi, Kathleen M. Dickson, Stephen J. Morris, Jon P. Durkin, Wai-Chi Ho, John W. Gillard, Snezana Milutinovic, Genevieve Doucet, Philip A. Barker
Publikováno v:
Chemistry & Biology. 13(2):213-223
SummaryWe describe a group of small-molecule inhibitors of Jun kinase (JNK)-dependent apoptosis. AEG3482, the parental compound, was identified in a screening effort designed to detect compounds that reduce apoptosis of neonatal sympathetic neurons a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd2a46e5ce7de7c31a892821d78043c8
Publikováno v:
Experimental Cell Research. 263:254-264
Rat pheochromocytoma PC12 cells have been widely used as a cell system for study of growth factor-stimulated cell functions. We report here that nerve growth factor (NGF) stimulated both chemotaxis (directional migration) and chemokinesis (random mig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::459601c9f5febd63412b72bcf554b18f
https://doi.org/10.1006/excr.2000.5112
https://doi.org/10.1006/excr.2000.5112
Publikováno v:
Biochemistry and Cell Biology. 77:409-420
It is well established that a biphasic relationship exists between the adhesive strength of β1 integrins and their ability to mediate cell movement. Thus, cell movement increases progressively with adhesive strength, but beyond a certain point of op
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4bc9d807506cc580a5be6e618e8bcd3e
https://doi.org/10.1139/o99-050
https://doi.org/10.1139/o99-050
Autor:
Wai Chi Ho, Stephanie Forte, Philip A. Barker, Kristy Favell, Kathleen M. Dickson, Jacqueline Boutilier, Alberto Javier Ramos
Publikováno v:
The Journal of neuroscience : the official journal of the Society for Neuroscience. 27(6)
Injury-induced expression of the p75 neurotrophin receptor (p75NTR) in the CNS facilitates neuronal apoptosis and prevents neuronal regrowth, but the mechanisms regulating p75NTR expression are poorly characterized. In this study, we showed that hypo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73e5030a6033d9fc403cc001a0d4e6ed
https://pubmed.ncbi.nlm.nih.gov/17287525
https://pubmed.ncbi.nlm.nih.gov/17287525