Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Wai-Ling Macrina Lam"'
Publikováno v:
Frontiers in Medicine, Vol 9 (2022)
BackgroundLines of evidence implicate CENPF and FOXM1 may have novel co-operative roles in driving hepatocellular carcinoma (HCC).ObjectiveWe investigated the clinicopathological correlation, functional characterization, molecular mechanism and trans
Externí odkaz:
https://doaj.org/article/5ce501daf7234e929e561c347eba45d4
Autor:
Jenna L Jewell, Vivian Fu, Audrey W Hong, Fa-Xing Yu, Delong Meng, Chase H Melick, Huanyu Wang, Wai-Ling Macrina Lam, Hai-Xin Yuan, Susan S Taylor, Kun-Liang Guan
Publikováno v:
eLife, Vol 8 (2019)
The mammalian target of rapamycin complex 1 (mTORC1) regulates cell growth, metabolism, and autophagy. Extensive research has focused on pathways that activate mTORC1 like growth factors and amino acids; however, much less is known about signaling cu
Externí odkaz:
https://doaj.org/article/f2cb47e5a18d47baab8d455fa1ea5eb2
Autor:
Wai Ling Macrina Lam, Amruta Damle-Vartak, Gisela Gabernet, Doris Schneller, Tanja Poth, Simone Jörs, Melanie Sator-Schmitt, Aurora De Ponti, Lena Weiß, Mathias Heikenwälder, Nachiket Vartak, Jan G. Hengstler, Fabian Geisler, Sven Nahnsen, Peter Angel
Publikováno v:
Journal of Hepatology. 77:S38
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9e23f2e9ca3771b146b74822d4c214ee
https://doi.org/10.1016/s0168-8278(22)00488-3
https://doi.org/10.1016/s0168-8278(22)00488-3
Autor:
Susan S. Taylor, Hai-Xin Yuan, Audrey W. Hong, Wai-Ling Macrina Lam, Delong Meng, Fa-Xing Yu, Chase H. Melick, Huanyu Wang, Vivian Fu, Kun-Liang Guan, Jenna L. Jewell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a17b3c783613ff13069310da91b95fe4
https://doi.org/10.7554/elife.43038.019
https://doi.org/10.7554/elife.43038.019
Autor:
Anna Saborowski, Aurora De Ponti, D Schneller, Peter Angel, Sven Nahnsen, Gisela Gabernet, Tanja Poth, Wai Ling Macrina Lam
Publikováno v:
Cancer Research. 80:5728-5728
Liver fibrosis is characterized by hepatic stellate cell activation and extracellular matrix deposition upon persistent injury and inflammation, which can impair hepatic function and its ability to regenerate. The origin and physiological role of fac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::316935910f2132cda2aeca08c4a1243e
https://doi.org/10.1158/1538-7445.am2020-5728
https://doi.org/10.1158/1538-7445.am2020-5728
Autor:
Hai Xin Yuan, Audrey W. Hong, Delong Meng, Fa-Xing Yu, Wai Ling Macrina Lam, Kun-Liang Guan, Susan S. Taylor, Jenna L. Jewell, Vivian Fu, Chase H. Melick, Huanyu Wang
Publikováno v:
eLife
eLife, Vol 8 (2019)
eLife, Vol 8 (2019)
The mammalian target of rapamycin complex 1 (mTORC1) regulates cell growth, metabolism, and autophagy. Extensive research has focused on pathways that activate mTORC1 like growth factors and amino acids; however, much less is known about signaling cu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ffb298648d804f7699381ac8a2b44fd
https://pubmed.ncbi.nlm.nih.gov/31112131
https://pubmed.ncbi.nlm.nih.gov/31112131
Publikováno v:
Cell Research, vol 25, iss 12
© 2015 Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences YAP and TAZ are transcriptional co-activators and function as the major effectors of the Hippo tumor suppressor pathway, which controls cell growth, tissue homeostasis,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6abf7af3465cb45534d66a798b76532
https://europepmc.org/articles/PMC4670996/
https://europepmc.org/articles/PMC4670996/
Publikováno v:
Cancer Research. 77:4848-4848
Hepatocellular carcinoma (HCC) is the second leading cause of cancer death worldwide and metastasis is regarded as the major cause of HCC-associated lethality. In this study, we have analysed the TCGA whole-transcriptome sequencing data of paired hum
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c9c1b0498f3789a40bad2f61df33c0a9
https://doi.org/10.1158/1538-7445.am2017-4848
https://doi.org/10.1158/1538-7445.am2017-4848