Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Wai-Kwan Alfred Yung"'
Autor:
Xiaowei Guan, Jaime Vengoechea, Siyuan Zheng, Andrew E Sloan, Yanwen Chen, Daniel J Brat, Brian Patrick O'Neill, John de Groot, Shlomit Yust-Katz, Wai-Kwan Alfred Yung, Mark L Cohen, Kenneth D Aldape, Steven Rosenfeld, Roeland G W Verhaak, Jill S Barnholtz-Sloan
Publikováno v:
PLoS ONE, Vol 9, Iss 3, p e91216 (2014)
BackgroundGliomas are the most common primary malignant brain tumors in adults with great heterogeneity in histopathology and clinical course. The intent was to evaluate the relevance of known glioblastoma (GBM) expression and methylation based subty
Externí odkaz:
https://doaj.org/article/11d06f53ffa14d86ae428b8cf35f5a14
Autor:
Hong Jiang, Karen Clise-Dwyer, Kathryn E Ruisaard, Xuejun Fan, Weihua Tian, Joy Gumin, Martine L Lamfers, Anne Kleijn, Frederick F Lang, Wai-Kwan Alfred Yung, Luis M Vence, Candelaria Gomez-Manzano, Juan Fueyo
Publikováno v:
PLoS ONE, Vol 9, Iss 5, p e97407 (2014)
Emerging evidence suggests anti-cancer immunity is involved in the therapeutic effect induced by oncolytic viruses. Here we investigate the effect of Delta-24-RGD oncolytic adenovirus on innate and adaptive anti-glioma immunity.Mouse GL261-glioma mod
Externí odkaz:
https://doaj.org/article/fb4673f3b2904821a7d5b9efeabd6a3b
Autor:
Simona Colla, Marta Moreno Monasterio, Luigi Nezi, Qianghu Wang, Derrick Sek Tong Ong, Shan Jiang, Charles Etienne Gabriel Sauvé, Y. Alan Wang, Ronald A. DePinho, Matteo Marchesini, Claire Elizabeth Gorman, Wai Kwan Alfred Yung, Lynda Chin, Denise J. Spring, Christopher A. Bristow, Peiwen Chen, Eun-Jung Jin, Baoli Hu, Erik P. Sulman, Dimpy Koul, Asha S. Multani, Yan Wing Ho, Roel G.W. Verhaak
An integrated genomic and functional analysis to elucidate DNA damage signaling factors promoting self-renewal of glioma stem cells (GSCs) identified proliferating cell nuclear antigen (PCNA)-associated factor (PAF) up-regulation in glioblastoma. PAF
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5959950adcb7e93f2abdff2b01295d12
https://europepmc.org/articles/PMC5664518/
https://europepmc.org/articles/PMC5664518/
Autor:
Brian M. Alexander, Patrick Y. Wen, David A. Reardon, Giovanni Parmigiani, Lorenzo Trippa, Donald A. Berry, Wai Kwan Alfred Yung
Publikováno v:
Neuro-Oncology. 15:972-978
The traditional clinical trials infrastructure may not be ideally suited to evaluate the numerous therapeutic hypotheses that result from the increasing number of available targeted agents combined with the various methodologies to molecularly subcla
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db80501e573680525be892a49b37eca7
https://doi.org/10.1093/neuonc/not088
https://doi.org/10.1093/neuonc/not088
Autor:
Basvoju A. Bhanu Prasad, Juri G. Gelovani, Duoli Sun, Zhenghong Peng, William G. Bornmann, Paul T. Schuber, Wai Kwan Alfred Yung, Yunming Ying, David Maxwell
Publikováno v:
Tetrahedron. 70(4)
A virtual library of 54 inositol analog mimics of In(1,4,5)P3 has been docked, scored, and ranked within the binding site of human inositol 1,4,5-trisphosphate 3-kinase A (IP3-3KA). Chemical synthesis of the best scoring structure that also met dista
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a856450f659a9d060150f8365cd0010
https://pubmed.ncbi.nlm.nih.gov/25110363
https://pubmed.ncbi.nlm.nih.gov/25110363
Autor:
Sek Tong Ong, Derrick, Baoli Hu, Yan Wing Ho, Sauvé, Charles-Etienne Gabriel, Bristow, Christopher A., Qianghu Wang, Multani, Asha S., Peiwen Chen, Nezi, Luigi, Shan Jiang, Gorman, Claire Elizabeth, Monasterio, Marta Moreno, Koul, Dimpy, Marchesini, Matteo, Colla, Simona, Eun-Jung Jin, Sulman, Erik P., Spring, Denise J., Wai-Kwan Alfred Yung, Verhaak, Roel G. W.
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America; 10/24/2017, Vol. 114 Issue 43, pE9086-E9095, 10p
Publikováno v:
Breast Cancer Research
Introduction Se-methylselenocysteine (MSC), a naturally occurring selenium compound, is a promising chemopreventive agent against in vivo and in vitro models of carcinogen-induced mouse and rat mammary tumorigenesis. We have demonstrated previously t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10218638e045d76b4da5582773b64768
https://pubmed.ncbi.nlm.nih.gov/16168115
https://pubmed.ncbi.nlm.nih.gov/16168115
Autor:
Howard J. Landy, K. F. Lee, Lynn G. Feun, Jeffery P. Kochan, C. Charnsangavej, Niramol Savaraj, Brian C. Bowen, Y. Y. Lee, J. Martinez-Prieto, Wai Kwan Alfred Yung, Judith D. Post, Sidney Wallace
Publikováno v:
Selective cancer therapeutics. 7(1)
Fifteen patients with progressive primary malignant or metastatic brain tumors were treated on a clinical and pharmacokinetic study with intracarotid cisplatin and bleomycin. Toxicity was tolerable and consisted mainly of nausea and vomiting. Neurolo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b99ce494610491611baf35e41d61611d
https://pubmed.ncbi.nlm.nih.gov/1718023
https://pubmed.ncbi.nlm.nih.gov/1718023
Publikováno v:
Journal of neuro-oncology. 4(4)
Twenty-eight patients with malignant brain tumors (16 with primary brain tumors and 12 with brain metastases) progressing after cranial irradiation with or without chemotherapy received varying doses of intracarotid VP-16. Courses of therapy were rep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e9cc8258fc36ae1955fdfd0616a83b4
https://pubmed.ncbi.nlm.nih.gov/3572470
https://pubmed.ncbi.nlm.nih.gov/3572470