Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Wai-Kin Mat"'
Autor:
Iram Shazia Tyagi, Ho Yin Calvin Tsui, Si Chen, Xinyi Li, Wai-Kin Mat, Muhammad A. Khan, Lucas Brendan Choy, Ka-Yin Aden Chan, Tat-Ming Danny Chan, Chi-Ping Stephanie Ng, Ho-Keung Ng, Wai Sang Poon, Hong Xue
Publikováno v:
Cell Division, Vol 19, Iss 1, Pp 1-15 (2024)
Abstract Introduction Anti-mitosis has been a key strategy of anti-cancer therapies, targeting at a fundamental property of cancer cells, their non-controllable proliferation due to overactive mitotic divisions. For improved anti-cancer therapies, it
Externí odkaz:
https://doaj.org/article/07f3251a2fde49b0933710dbc4ed1c16
Publikováno v:
Clinical and Translational Discovery, Vol 2, Iss 2, Pp n/a-n/a (2022)
Abstract Background While next generation sequencing (NGS) has enabled massive parallel analysis of different human genomes, strategies are required to maximize its signal‐to‐noise ratio in the data generated and its accessibility for clinical se
Externí odkaz:
https://doaj.org/article/6bda7163b29c4fe5ada0b9c9dfa07606
Autor:
Ata Ullah, Xi Long, Wai-Kin Mat, Taobo Hu, Muhammad Ismail Khan, Li Hui, Xiangyang Zhang, Peng Sun, Mingzhou Gao, Jieqiong Wang, Haijun Wang, Xia Li, Wenjun Sun, Mingqi Qiao, Hong Xue
Publikováno v:
Frontiers in Psychiatry, Vol 11 (2020)
ObjectiveAlthough single-nucleotide polymorphisms in GABRB2, the gene encoding for GABAA receptors β2 subunit, have been associated with schizophrenia (SCZ), it is unknown whether there is any association of copy number variations (CNVs) in this gen
Externí odkaz:
https://doaj.org/article/f53c15cf2019429ebcc4760514cac41b
Autor:
Taobo Hu, Yogesh Kumar, Iram Shazia, Shen-Jia Duan, Yi Li, Lei Chen, Jin-Fei Chen, Rong Yin, Ava Kwong, Gilberto Ka-Kit Leung, Wai-Kin Mat, Zhenggang Wu, Xi Long, Cheuk-Hin Chan, Si Chen, Peggy Lee, Siu-Kin Ng, Timothy Y. C. Ho, Jianfeng Yang, Xiaofan Ding, Shui-Ying Tsang, Xuqing Zhou, Dan-Hua Zhang, the International Cancer Genome Consortium, En-Xiang Zhou, Lin Xu, Wai-Sang Poon, Hong-Yang Wang, Hong Xue
Publikováno v:
Human Genomics, Vol 12, Iss 1, Pp 1-21 (2018)
Abstract Background Massive occurrences of interstitial loss of heterozygosity (LOH) likely resulting from gene conversions were found by us in different cancers as a type of single-nucleotide variations (SNVs), comparable in abundance to the commonl
Externí odkaz:
https://doaj.org/article/1591b03b450f4e6cad6284f2e1e6ce94
Autor:
Yung Su Kim, Mei Yang, Wai-Kin Mat, Shui-Ying Tsang, Zhonghua Su, Xianfei Jiang, Siu-Kin Ng, Siyu Liu, Taobo Hu, Frank Pun, Yanhui Liao, Jinsong Tang, Xiaogang Chen, Wei Hao, Hong Xue
Publikováno v:
PLoS ONE, Vol 10, Iss 11, p e0142049 (2015)
Substance dependence is a frequently observed comorbid disorder in schizophrenia, but little is known about genetic factors possibly shared between the two psychotic disorders. GABRB2, a schizophrenia candidate gene coding for GABAA receptor β2 subu
Externí odkaz:
https://doaj.org/article/adc669392acb4bf6be69e29b030ff84c
Publikováno v:
Life, Vol 6, Iss 1, p 12 (2016)
The origins of the components of genetic coding are examined in the present study. Genetic information arose from replicator induction by metabolite in accordance with the metabolic expansion law. Messenger RNA and transfer RNA stemmed from a templat
Externí odkaz:
https://doaj.org/article/ea88d435c7664170bc7ed6462b5216d5
Publikováno v:
PLoS ONE, Vol 5, Iss 8, p e12206 (2010)
The genetic code has been unchanging for some three billion years in its canonical ensemble of encoded amino acids, as indicated by the universal adoption of this ensemble by all known organisms. Code mutations beginning with the encoding of 4-fluoro
Externí odkaz:
https://doaj.org/article/a0253a7b71ec445780c97023df2d5ba3
Autor:
Zhenggang Wu, Xi Long, Shui Ying Tsang, Taobo Hu, Jian-Feng Yang, Wai Kin Mat, Hongyang Wang, Hong Xue
Publikováno v:
BMC Cancer, Vol 20, Iss 1, Pp 1-13 (2020)
Abstract Background Cancer subtyping has mainly relied on pathological and molecular means. Massively parallel sequencing-enabled subtyping requires genomic markers to be developed based on global features rather than individual mutations for effecti
Externí odkaz:
https://doaj.org/article/227425300bc14067bb1133c07a937370
Autor:
Xi Long, Hong Xue, Taobo Hu, Hongyang Wang, Shui Ying Tsang, Jianfeng Yang, Wai-Kin Mat, Zhenggang Wu
Publikováno v:
BMC Cancer, Vol 20, Iss 1, Pp 1-13 (2020)
BMC Cancer
BMC Cancer
Background Cancer subtyping has mainly relied on pathological and molecular means. Massively parallel sequencing-enabled subtyping requires genomic markers to be developed based on global features rather than individual mutations for effective implem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c23b63d48163c8114f76c3c008636480
https://doaj.org/article/227425300bc14067bb1133c07a937370
https://doaj.org/article/227425300bc14067bb1133c07a937370
Autor:
Zhenggang Wu, Xi Long, Hong Xue, Xia Li, Peng Sun, Mingzhou Gao, Wenjun Sun, Wang Jieqiong, Si Chen, Wai-Kin Mat, Ata Ullah, Mingqi Qiao, Wang Haijun
Publikováno v:
Journal of genetics and genomics = Yi chuan xue bao. 48(12)
Premenstrual dysphoric disorder (PMDD) affects nearly 5% of women of reproductive age. Symptomatic heterogeneity, together with largely unknown genetics, has greatly hindered its effective treatment. In the present study, analysis of genomic sequenci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34d36f05a0bcaa068443614a5537780b
https://pubmed.ncbi.nlm.nih.gov/34530168
https://pubmed.ncbi.nlm.nih.gov/34530168