Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Wai Yee Phong"'
Publikováno v:
PLoS ONE, Vol 8, Iss 11 (2013)
Externí odkaz:
https://doaj.org/article/f7c1dabfe14f4b4d97f40f6c75ed7c56
Publikováno v:
PLoS ONE, Vol 8, Iss 2, p e56037 (2013)
Metabolic versatility has been increasingly recognized as a major virulence mechanism that enables Mycobacterium tuberculosis to persist in many microenvironments encountered in its host. Glucose is one of the most abundant carbon sources that is exp
Externí odkaz:
https://doaj.org/article/20f90622311042d7ad4b1f267d59ca0f
Autor:
Mai Ping Tan, Patricia Sequeira, Wen Wei Lin, Wai Yee Phong, Penelope Cliff, Seow Hwee Ng, Boon Heng Lee, Luis Camacho, Dirk Schnappinger, Sabine Ehrt, Thomas Dick, Kevin Pethe, Sylvie Alonso
Publikováno v:
PLoS ONE, Vol 5, Iss 10, p e13356 (2010)
There are strong evidences that Mycobacterium tuberculosis survives in a non-replicating state in the absence of oxygen in closed lesions and granuloma in vivo. In addition, M. tuberculosis is acid-resistant, allowing mycobacteria to survive in acidi
Externí odkaz:
https://doaj.org/article/cdb947bf7d294f19b849e7705ac8e9c1
Autor:
Nicole J. Moreland, Wai Yee Phong, Prasad N. Paradkar, Subhash G. Vasudevan, Daying Wen, Siew Pheng Lim
Publikováno v:
Bioscience Reports. 31:399-409
Flaviviral NS3 serine proteases require the NS2B cofactor region (cNS2B) to be active. Recent crystal structures of WNV (West Nile virus) protease in complex with inhibitors revealed that cNS2B participates in the formation of the protease active sit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2817e5eea39ea0f273b7d1a613090d89
https://doi.org/10.1042/bsr20100142
https://doi.org/10.1042/bsr20100142
Autor:
Feng Gu, Mee Kian Poh, Wai Yee Phong, Subhash G. Vasudevan, Edgar Jacoby, Olivier Heudi, Hao Ying Xu, Deana Jaber, Sejal J. Patel, Ngai Ling Ma, Ranga Rao, Wouter Schul, Eric Vangrevelinghe, Thomas H. Keller, Qing-Yin Wang
Publikováno v:
Antimicrobial Agents and Chemotherapy. 53:1823-1831
The incidence of dengue fever epidemics has increased dramatically over the last few decades. However, no vaccine or antiviral therapies are available. Therefore, the need for safe and effective antiviral drugs has become imperative. The entry of den
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::860f8efa995a625b6264862dabe5459c
https://doi.org/10.1128/aac.01148-08
https://doi.org/10.1128/aac.01148-08
Publikováno v:
PLoS ONE, Vol 8, Iss 2, p e56037 (2013)
PLoS ONE
PLoS ONE
Metabolic versatility has been increasingly recognized as a major virulence mechanism that enables Mycobacterium tuberculosis to persist in many microenvironments encountered in its host. Glucose is one of the most abundant carbon sources that is exp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28ab9387445e1fbde94ac046791d4169
http://europepmc.org/articles/PMC3567006?pdf=render
http://europepmc.org/articles/PMC3567006?pdf=render
Autor:
Patricia C. Sequeira, Richard Glynne, Michael H. Cynamon, Pamela Thayalan, Mai Ping Tan, Kyu Y. Rhee, David Beer, Xiuhua Lin, John R. Walker, Manjunatha Ujjini, Zhong Chen, Carolyn Shoen, Bee Huat Tan, Puiying A. Mak, Sydney Brenner, Srinivasa P. S. Rao, Ida Ma, Eric C. Peters, Suresh B. Lakshminarayana, Pablo Bifani, David Plouffe, Kelli Kuhen, S. Whitney Barnes, Jeyaraj Duraiswamy, Boon Heng Lee, Sindhu Ravindran, Sanjay Agarwalla, Kevin Pethe, Arnab K. Chatterjee, Thomas Dick, Barry N. Kreiswirth, Thomas H. Keller, Anne Goh, Wai Yee Phong, Véronique Dartois, Seow Hwee Ng, Mahesh Nanjundappa, Viral Patel, Melvin Au, Jan Jiricek, Luis R. Camacho
Publikováno v:
Nature Communications
Candidate antibacterials are usually identified on the basis of their in vitro activity. However, the apparent inhibitory activity of new leads can be misleading because most culture media do not reproduce an environment relevant to infection in vivo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93a4829d8ce2cee9a74a8afa0de5f4be
https://doi.org/10.1038/ncomms1060
https://doi.org/10.1038/ncomms1060
Autor:
Kristina Löhr, Sejal J. Patel, John E. Knox, Thomas H. Keller, Subhash G. Vasudevan, Gang Wang, Zheng Yin, Ngai Ling Ma, Wai-Ling Chan, Weiling Wang, Wai Yee Phong, K. R. Ranga Rao, Aruna Sampath, Siew Pheng Lim
Publikováno v:
The Journal of general virology. 88(Pt 8)
A recombinant form of yellow fever virus (YFV) NS3 protease, linked via a nonapeptide to the minimal NS2B co-factor sequence (CF40-gly-NS3pro190), was expressed in Escherichia coli and shown to be catalytically active. It efficiently cleaved the fluo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a364c842c557bea4dee17a6d0cf9c0d4
https://pubmed.ncbi.nlm.nih.gov/17622626
https://pubmed.ncbi.nlm.nih.gov/17622626
Autor:
Chuan Young Ng, Andrew D. Davidson, Subhash G. Vasudevan, Feng Gu, Wai Yee Phong, Yen Liang Chen, Siew Pheng Lim
Publikováno v:
Antiviral research. 76(3)
Self-replicating, non-infectious flavivirus subgenomic replicons have been broadly used in the studies of trans-complementation, adaptive mutation, viral assembly and packaging in Kunjin, yellow fever and West Nile viruses. We describe here the const
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c5f00ba2c094e5189b0e1d653c5bd1e
https://pubmed.ncbi.nlm.nih.gov/17662475
https://pubmed.ncbi.nlm.nih.gov/17662475