Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Wai W. Lin"'
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-12 (2019)
Abstract TRAF3 is a versatile intracellular adapter protein with multiple context-specific roles. Uniquely in B cells, TRAF3 deficiency enhances survival and increases the risk of transformation, as loss of TRAF3 is observed in several types of B cel
Externí odkaz:
https://doaj.org/article/cabe35fe3e8245a3acd52f3226bbe784
Autor:
Thiago Detanico, Richard Virgen-Slane, Seth Steen-Fuentes, Wai W. Lin, Antje Rhode-Kurnow, Elizabeth Chappell, Ricardo G. Correa, Michael J. DiCandido, M. Lamine Mbow, Jun Li, Carl F. Ware
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Genome-wide co-expression analysis is often used for annotating novel gene functions from high-dimensional data. Here, we developed an R package with a Shiny visualization app that creates immuno-networks from RNAseq data using a combination of Weigh
Externí odkaz:
https://doaj.org/article/6c853fe984614df19760a4a5d7dfb5f2
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-12 (2019)
Scientific Reports
Scientific Reports
TRAF3 is a versatile intracellular adapter protein with multiple context-specific roles. Uniquely in B cells, TRAF3 deficiency enhances survival and increases the risk of transformation, as loss of TRAF3 is observed in several types of B cell cancers
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8396945d9d525e691c93c3d4605cd477
https://doaj.org/article/cabe35fe3e8245a3acd52f3226bbe784
https://doaj.org/article/cabe35fe3e8245a3acd52f3226bbe784
Publikováno v:
Scientific Reports
Scientific Reports, Vol 9, Iss 1, Pp 1-1 (2019)
Scientific Reports, Vol 9, Iss 1, Pp 1-1 (2019)
TRAF3 is a versatile intracellular adapter protein with multiple context-specific roles. Uniquely in B cells, TRAF3 deficiency enhances survival and increases the risk of transformation, as loss of TRAF3 is observed in several types of B cell cancers
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::434c45d006fe10b599f1d1089f1390bc
http://europepmc.org/articles/PMC6864106
http://europepmc.org/articles/PMC6864106
Autor:
Numana Bhat, Ashima Shukla, Wai W Lin, Cindi Chen, Robert C. Rickert, Elaine Kao, Charlotte R Leung, John R Apgar, Julia Jellusova
Publikováno v:
JCI Insight. 4
Immune homeostasis in the gut-associated lymphoid tissues (GALT) is critical to prevent the development of inadvertent pathologies. B cells, as the producers of antibodies and cytokines, play an important role in maintaining the GALT homeostasis. How
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9fecac6e80575a0aac013fa08713111
https://doi.org/10.1172/jci.insight.130621
https://doi.org/10.1172/jci.insight.130621
Publikováno v:
The Journal of Immunology. 202:62.8-62.8
The herpes virus entry mediator (HVEM) a member of the TNFR superfamily, is a key immunoregulator with both proinflammatory and inhibitory signaling functions. Both α and β-herpes viruses exploit HVEM to establish persistent infections, however lit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::799f50b2baab72ef3a6ffe67a3424735
https://doi.org/10.4049/jimmunol.202.supp.62.8
https://doi.org/10.4049/jimmunol.202.supp.62.8
Publikováno v:
Scientific Reports
The adaptor protein TNF receptor-associated factor 3 (TRAF3) is a critical regulator of B lymphocyte survival. B cell-specific TRAF3 deficiency results in enhanced viability and is associated with development of lymphoma and multiple myeloma. We show
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4851265430035450e083a0cb764a4026
Autor:
Nurbek Mambetsariev, Wai W. Lin, Laura L. Stunz, Brett M. Hanson, Gail A. Bishop, Joanne M Hildebrand
The adaptor protein TNF receptor-associated factor 3 (TRAF3) regulates signaling through B-lymphocyte receptors, including CD40, BAFF receptor, and Toll-like receptors, and also plays a critical role inhibiting B-cell homoeostatic survival. Consisten
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6b40c0b87a89574838c7472cf5b8dca
https://europepmc.org/articles/PMC4743771/
https://europepmc.org/articles/PMC4743771/
Publikováno v:
The Journal of Immunology. 200:116.7-116.7
Tumor necrosis factor receptor associated factor 3 (TRAF3) is an adaptor protein that plays an important role in B cell homeostasis. TRAF3 deletions or inactivating mutations are common in human B cell malignancies. In human and mouse B cells, TRAF3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2bef36a586f00955de4359ca625fecbf
https://doi.org/10.4049/jimmunol.200.supp.116.7
https://doi.org/10.4049/jimmunol.200.supp.116.7
Publikováno v:
Science Signaling. 8
Tumor necrosis factor receptor-associated factor 3 (TRAF3) is an adaptor protein that inhibits signaling by CD40 and by the receptor for B cell-activating factor (BAFF) and negatively regulates homeostatic B cell survival. Loss-of-function mutations
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05ab1049253ed2520fb8215961f8aa3f
https://doi.org/10.1126/scisignal.aaa5157
https://doi.org/10.1126/scisignal.aaa5157