Výsledky vyhledávání - "Wai Theng Lee"

Repositioning antipsychotic chlorpromazine for treating colorectal cancer by inhibiting sirtuin 1

Autor: Min Siou Sun, Chih Ming Chou, Hung Wei Cheng, Wai Theng Lee, Meng Ni Ho, Cheng Wei Lin, Chu Hung Chung, Wen Ying Lee, Ku Chung Chen, Chia Hsiung Cheng

Publikováno v: Oncotarget

Investigating existing drugs for repositioning can enable overcoming bottlenecks in the drug development process. Here, we investigated the effect and molecular mechanism of the antipsychotic drug chlorpromazine (CPZ) and identified its potential for

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8875fd059e9dbb54ca385d12488a488
https://pubmed.ncbi.nlm.nih.gov/26363315

Zobrazit plný text záznamu

Antroquinonol from Antrodia Camphorata suppresses breast tumor migration/invasion through inhibiting ERK-AP-1- and AKT-NF-κB-dependent MMP-9 and epithelial-mesenchymal transition expressions

Autor: Ku-Chung Chen, Chia Hsiung Cheng, Wai-Theng Lee, Yen-Chou Chen, Tzong-Huei Lee, Cheng Wei Lin

Publikováno v: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 78

Antroquinonol (ANQ) is an ubiquinon derivative isolated from the mycelium of Antrodia camphorata. However, the effect of ANQ on breast cancer treatment is unknown. We found that ANQ significantly suppressed the migration and invasion of breast cancer

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa4ee4da4d86338b14c7ab37f14505d4
https://pubmed.ncbi.nlm.nih.gov/25656647

Zobrazit plný text záznamu

Induction of ROS-independent JNK-activation-mediated apoptosis by a novel coumarin-derivative, DMAC, in human colon cancer cells

Autor: Ku Chung Chen, Yen Fang Wang, Mei Hsiang Lin, Chia Hsiung Cheng, Cai Qin Xiao, Wai Theng Lee, Cheng Wei Lin

Publikováno v: Chemico-biological interactions. 218

In this study, we investigated the antitumor activity of a novel coumarin derivative, 5,7-dihydroxy-4-methyl-6-(3-methylbutanoyl)-coumarin (DMAC), on colorectal carcinoma. DMAC treatment resulted in substantial proapoptotic activity against colon can

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc9506d5febfe2c170291fbabb832e39
https://pubmed.ncbi.nlm.nih.gov/24812029

Zobrazit plný text záznamu

Akademický článek

Induction of ROS-independent JNK-activation-mediated apoptosis by a novel coumarin-derivative, DMAC, in human colon cancer cells.

Autor: Mei-Hsiang Lin¹, Chia-Hsiung Cheng^2,3, Ku-Chung Chen², Wai-Theng Lee³, Yen-Fang Wang³, Cai-Qin Xiao³, Cheng-Wei Lin²

Publikováno v: Chemico-Biological Interactions. Jul2014, Vol. 218, p42-49. 8p.

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání