Zobrazeno 1 - 10
of 73
pro vyhledávání: '"Wai Mun, Huang"'
Publikováno v:
PLoS Biology, Vol 11, Iss 1, p e1001472 (2013)
Hairpin telomeres of bacterial linear chromosomes are generated by a DNA cutting-rejoining enzyme protelomerase. Protelomerase resolves a concatenated dimer of chromosomes as the last step of chromosome replication, converting a palindromic DNA seque
Externí odkaz:
https://doaj.org/article/b4a4e841c0f04b3abfb510efe423257e
Genome stability of Lyme disease spirochetes: comparative genomics of Borrelia burgdorferi plasmids.
Autor:
Sherwood R Casjens, Emmanuel F Mongodin, Wei-Gang Qiu, Benjamin J Luft, Steven E Schutzer, Eddie B Gilcrease, Wai Mun Huang, Marija Vujadinovic, John K Aron, Levy C Vargas, Sam Freeman, Diana Radune, Janice F Weidman, George I Dimitrov, Hoda M Khouri, Julia E Sosa, Rebecca A Halpin, John J Dunn, Claire M Fraser
Publikováno v:
PLoS ONE, Vol 7, Iss 3, p e33280 (2012)
Lyme disease is the most common tick-borne human illness in North America. In order to understand the molecular pathogenesis, natural diversity, population structure and epizootic spread of the North American Lyme agent, Borrelia burgdorferi sensu st
Externí odkaz:
https://doaj.org/article/3c59c5552f0541c5970eb094a0a12062
Autor:
Wai Mun Huang, Qiurong Ruan, Jeanne DaGloria, Ke Shi, Heather Fox, Sherwood R. Casjens, John Aron, John Tillou, Hideki Aihara
Publikováno v:
Journal of Biological Chemistry. 287:25551-25563
Background: Protelomerase is an enzyme that generates closed hairpin ends in bacterial linear chromosomes. Results: Atu2523 encodes the agrobacterial protelomerase that generates its telomeres. Conclusion: Agrobacterial protelomerase is the most comp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d87a734c40f6c79788334a54d0e6340c
https://doi.org/10.1074/jbc.m112.369488
https://doi.org/10.1074/jbc.m112.369488
Autor:
Raymond F. Gesteland, Wai Mun Huang, Charles C. Rettberg, Chad C. Nelson, John F. Atkins, Norma M. Wills, Michelle O’Connor
Publikováno v:
The EMBO Journal. 27:2533-2544
Half the ribosomes translating the mRNA for phage T4 gene 60 topoisomerase subunit bypass a 50 nucleotide coding gap between codons 46 and 47. The pairing of codon 46 with its cognate peptidyl-tRNA anticodon dissociates, and following mRNA slippage,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de1e1a53d20308b4e62c044180f0519d
https://doi.org/10.1038/emboj.2008.170
https://doi.org/10.1038/emboj.2008.170
Publikováno v:
Journal of Biological Chemistry. 279:55587-55593
Bacteria possess two closely related yet functionally distinct essential type IIA topoisomerases (Topos). DNA gyrase supports replication and transcription with its unique supercoiling activity, whereas Topo IV preferentially relaxes (+) supercoils a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::77a2b1199be8c7fc9fbf3adfd6f11785
https://doi.org/10.1074/jbc.m408934200
https://doi.org/10.1074/jbc.m408934200
Publikováno v:
Cell
Bacteriophage T4 DNA topoisomerase gene 60 contains a 50 nucleotide untranslated region within the coding sequence of its mRNA. Translational bypass of this sequence by elongating ribosomes has been postulated for the mode of synthesis of an 18 kd po
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea715eedfbd52ed5c21abf0dcf89c44d
http://europepmc.org/articles/PMC7133334
http://europepmc.org/articles/PMC7133334
Publikováno v:
Journal of Molecular Biology. 337:77-92
Protelomerases are enzymes responsible for the generation of closed hairpin ends in linear DNA. It is proposed that they use a breaking-and-rejoin type mechanism to affect DNA rearrangement on specific DNA sequences. In doing so, one strand turns aro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6c9a719d41025a85700f2f000b184d2
https://doi.org/10.1016/j.jmb.2004.01.012
https://doi.org/10.1016/j.jmb.2004.01.012
Autor:
René Van Vugt, Michelle L. Gwinn, Daniel H. Haft, Jeremy Peterson, Erin Hickey, Raju Lathigra, Sherwood R. Casjens, Wai Mun Huang, Claire M. Fraser, Patricia A. Rosa, Robert J. Dodson, Granger G. Sutton, Owen White, Brian Stevenson, Nanette Palmer
Publikováno v:
Molecular Microbiology. 35:490-516
We have determined that Borrelia burgdorferi strain B31 MI carries 21 extrachromosomal DNA elements, the largest number known for any bacterium. Among these are 12 linear and nine circular plasmids, whose sequences total 610 694 bp. We report here th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5e6ff7cce69007c679c7bcc7740b1473
https://doi.org/10.1046/j.1365-2958.2000.01698.x
https://doi.org/10.1046/j.1365-2958.2000.01698.x
Publikováno v:
Antimicrobial Agents and Chemotherapy. 43:2493-2496
The role of mutations in the genes for GyrA and ParC in quinolone resistance in Mycoplasma hominis was studied. Selection with sparfloxacin gave mutations at GyrA83 (Ser→Leu; Escherichia coli numbering) or GyrA87 (Glu→Lys), and mutants had increa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8139f898a6a9f5e3e9903107c6cb3761
https://doi.org/10.1128/aac.43.10.2493
https://doi.org/10.1128/aac.43.10.2493
Autor:
James H. Jorgensen, Jan E. Patterson, David P. Dooley, Wai Mun Huang, Christine C. Sanders, Patricia A. Meier
Publikováno v:
Journal of Infectious Diseases. 177:951-954
Campylobacter fetus subspecies fetus has been recognized as a cause of systemic illness in immunocompromised hosts, including relapsing bacteremia in human immunodeficiency virus (HIV)-in-fected patients. Acquired resistance to quinolone therapy, whi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f878237cca1df97f84997a3c56e74ddc
https://doi.org/10.1086/515248
https://doi.org/10.1086/515248